Results 111 to 120 of about 182,785 (292)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

The Arctic Ocean Double Estuary: Quantification and Forcing Mechanisms

AGU Advances
The Arctic Ocean double estuary is a “three‐legged” overturning system in which inflowing waters are converted into both lighter and denser waters before being exported equatorwards.
Nikki J. Brown, Alberto C. Naveira Garabato, Sheldon Bacon, Yevgeny Aksenov, Takamasa Tsubouchi, Mattias Green, Ben Lincoln, Tom Rippeth, Daniel L. Feltham   +8 more
doaj   +1 more source

The local wavenumber model for computation of turbulent mixing. [PDF]

Philos Trans A Math Phys Eng Sci, 2022
Kurien S, Pal N.
europepmc   +1 more source

Analytical investigation of incompressible turbulent swirling flow in pipes [PDF]

Mixing length flow theory for analyzing incompressible turbulent swirling flow in ...
Lavan, Z., Rochino, A. P.
core   +1 more source

Turbulent Mixing in the Outer Solar Nebula

, 2005
The effects of turbulence on the mixing of gases and dust in the outer Solar nebula are examined using 3-D MHD calculations in the shearing-box approximation with vertical stratification.
G. Bryden, H. W. Yorke, K. Willacy, N. J. Turner, Suttner G.   +4 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Compressibility effects on fluid entrainment by turbulent mixing layers [PDF]

Compressibility effects on fluid entrainment by supersonic turbulent mixing ...
Hill, J. A. F., Nicholson, J. E.
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Characterization of Turbulent Processes by the Raman Lidar System Basil in the Frame of the HD(CP)2 Observational Prototype Experiment – Hope

EPJ Web of Conferences, 2016
Measurements carried out by the Raman lidar system BASIL are reported to demonstrate the capability of this instrument to characterize turbulent processes within the Convective Boundary Layer (CBL).
Di Girolamo Paolo, Summa Donato, Stelitano Dario, Cacciani Marco, Scoccione Andrea, Behrendt Andreas, Wulfmeyer Volker   +6 more
doaj   +1 more source

Fuel Spray Diagnostics [PDF]

, 1983
Fundamental experimental data base for turbulent flow mixing models is provided and better prediction of the more complex turbulent chemical reacting flows.
Bosque, M. A., Humenik, F. M.
core   +1 more source