Results 71 to 80 of about 4,220,519 (287)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Monetary policy and risk taking : [draft january 2013] [PDF]

open access: yes, 2013
We assess the effects of monetary policy on bank risk to verify the existence of a risk-taking channel - monetary expansions inducing banks to assume more risk. We first present VAR evidence confirming that this channel exists and tends to concentrate on
Angeloni, Ignazio   +2 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Analyzing classroom interactions focusing on IRF patterns and turn-taking

open access: yesEnglish Learning Innovation
This study aims to analyze patterns of interaction and turn-taking in the context of classroom learning using a classroom discourse analysis approach.
Efendi Hidayatullah
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Conditional Cooperation and Turn-Taking in Parental Care

open access: yesFrontiers in Ecology and Evolution, 2019
Sexual conflict is inescapable when two parents care for offspring, because providing care is personally costly, while the benefits of successful reproduction are shared.
Rufus A. Johnstone   +2 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

ORGANISATION AND ALLOCATION OF TURNS AT THE OPUTA PANEL SESSIONS

open access: yesJournal of Central and Eastern European African Studies
This study investigates the turn-taking sequence, organisation of turns and the question patterns adopted during the examination of witnesses at the Oputa Panel sessions.
Oluwakemi Olayemi
doaj   +1 more source

Classroom interaction: Turn-taking as a pedagogical strategy

open access: yesPer Linguam : A Journal of Language Learning, 2010
This paper reports on findings of a case study which analysed classroom interaction through turn-taking in Grade 4 science lessons taught through the medium of a home language and an additional language.
Nomlomo,Vuyokazi
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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