Trajectories of Symptom Severity in Children with Autism: Variability and Turning Points through the Transition to School. [PDF]
J Autism Dev Disord, 2022 Georgiades S +16 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
A longitudinal study of the turning points and trajectories of therapeutic relationship development in occupational and physical therapy. [PDF]
BMC Health Serv Res, 2021 Horton A, Hebson G, Holman D.
europepmc +1 more source
Turning Points in the U.S. Civil War: A British Perspective [PDF]
This paper examines the Confederate cotton bonds floated in Europe in March 1863 and traded on the London market. Over our March 27, 1863 to June 17, 1865 sample we isolate two, non-reversed, "turning points" that follow news of Confederate defeat at ...
Richard C.K. Burdekin +1 more
core
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
RLIM: a recursive and latent infection model for the prediction of US COVID-19 infections and turning points. [PDF]
Nonlinear Dyn, 2021 Yu X +5 more
europepmc +1 more source
Identifying and Forecasting the Turning Points of the Belgian Business Cycle with Regime-Switching and Logit Models [PDF]
This paper seeks to elaborate econometric models that can be used to forecast the turning points of the Belgian business cycle. We begin by suggesting three reference cycle, which we hope will fill the void of an official reference chronology for Belgium.
Fati, SHADMAN-MEHTA +2 more
core
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
Age-Graded Transitions and Turning Points in Polish Offenders' Criminal Careers from the Standpoint of Life Course Theory. [PDF]
Int J Environ Res Public Health, 2021 Pękala K +8 more
europepmc +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source