Results 71 to 80 of about 1,412,477 (278)
Forecasting Metals Returns A Bayesian Decision Theoretic Approach [PDF]
Turning points in commodity returns are important for decisions of policy makers, commodity producers and consumers reliant on medium term outcomes.
David Halperin
core
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Моделирование и анализ информационных систем, 2015 We consider a linear differential equation of second order with a small factor at the highest derivative. We study the problem of the asymptotic behavior of the eigenvalues of the first boundary value problem (task Dirichlet) in situation when the turning ...
S. A. Kaschenko
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
International Journal of Mathematics and Mathematical Sciences, 1988 The Lagrange manifold formalism is adapted to study the time-evolution of caustics associated with high frequency wave propagation in media with both spatial and temporal inhomogenities.
Nasit Ari, Arthur D. Gorman
doaj +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Level crossings and turning points of random hyperbolic polynomials
International Journal of Mathematics and Mathematical Sciences, 1999 In this paper, we show that the asymptotic estimate for the expected number of K-level crossings of a random hyperbolic polynomial a1sinhx+a2sinh2x+⋯+ansinhnx, where aj(j=1,2,…,n) are independent normally distributed random variables with mean zero and ...
K. Farahmand, P. Hannigan
doaj +1 more source
A Classifying Procedure for Signaling Turning Points [PDF]
A Hidden Markov Model (HMM) is used to classify an out of sample observation vector into either of two regimes. This leads to a procedure for making probability forecasts for changes of regimes in a time series, i.e. for turning points.
Koskinen, Lasse, Öller, Lars-Erik
core