Results 211 to 220 of about 395,966 (258)

Dual effects of Tween 80 on protein stability

International Journal of Pharmaceutics, 2008
In this paper, we used IL-2 mutein as a model protein and evaluated the effect of Tween 80, a non-ionic surfactant. In summary, we found that the dual effects of Tween 80 on the stability of IL-2SA, such as that shaking-induced aggregation of IL-2 mutein was significantly inhibited in the presence of Tween 80.
D Q Wang, Y John Wang
exaly   +3 more sources

Complex Micellization Behavior of the Polysorbates Tween 20 and Tween 80

Molecular Pharmaceutics, 2021
Polysorbates (PSs, Tweens) are widely used surfactant products consisting of a sorbitan ring connecting up to four ethylene oxide (EO) chains of variable lengths, one or more of which are esterified with fatty acids of variable lengths and saturation degrees.
Hannah Knoch, Maximilian H. Ulbrich, Judith J. Mittag, Julia Buske, Patrick Garidel, Heiko Heerklotz   +5 more
openaire   +3 more sources

The Effect of “Tween-65” and “Tween-80” on Gastrointestinal Motility in Man

Gastroenterology, 1953
Summary 1.The effect on gastrointestinal motility of ingesting 9 gm. of either Tween65 or Tween-80 for 13 successive days was studied in 24 normal individuals, and was compared with equal amounts of a placebo under similar conditions. 2.No subjective reactions or changes in bowel habit, character of stools, and body weight were induced by 117 gm ...
H D, JANOWITZ, F, HOLLANDER, R H, MARSHAK   +2 more
openaire   +2 more sources

Comparative Analysis of the Properties of Tween‐20, Tween‐60, Tween‐80, Arlacel‐60, and Arlacel‐80

Journal of Dispersion Science and Technology, 2007
Foamability and foam stability, emulsifying power, surface tension, and interfacial tension were investigated for Tween‐20 (polyoxyethylene sorbitan monolaurate), Tween‐60 (polyoxyethylene sorbitan monostearate), Tween‐80 (polyoxyethylene sorbitan monooleate), Arlacel‐60 (Sorbitan stearate), and Arlacel‐80 (Sorbitan oleate).
Shrinivas C. Kothekar, Adinath M. Ware, Jyotsna T. Waghmare, S. A. Momin   +3 more
openaire   +1 more source

Comparative study on pseudoanaphylactoid reactions induced by medicinal tween 80 and injectable tween 80

China Journal of Chinese Materia Medica, 2012
OBJECTIVE To investigate the safety of different level of tween 80 by comparing the degree of pseudoanaphylactoid reactions (PR) induced by medicinal tween 80 and injectable tween 80. METHOD The analysis of vascular permeability of the mice ears: ICR mouse were divided into different test groups, the mice were intravenously injected with solutions of ...
Yunting, Wang, Chunying, Li, Yan, Yi, Lin, Qin, Yong, Zhao, Guiqing, Li, Xudong, Cong, Sumin, Cao, Aihua, Liang   +8 more
openaire   +3 more sources

Kinetic spectrophotometric determination of Tween 80

Talanta, 2004
A novel kinetic spectrophotometic method for the determination of Tween 80 based on its interaction with 5(p-dimethylaminobenzylidene)rhodanine (PDR) in alkaline media is reported. The effect of variable on the rate of interaction of Tween 80 and PDR was investigated in order to establish the optimum conditions.
N, Pourreza, S, Rastegarzadeh
openaire   +2 more sources

The Hydrolysis of Tween 80 by Vibrios and Aeromonads

Journal of Applied Bacteriology, 1970
Summary. A total of 307 strains consisting of 89 Vibrio cholerae , 37 NAG vibrios, 4 Aeromonas sp., 20 Pseudomonas aeruginosa , 47 shigellae, 59 Escherichia coli
A N, Chakrabarty, S, Adhya, M K, Pramanik   +2 more
openaire   +2 more sources

Enhancement of fibrinolysis and thrombolysis by polysorbate 80 (Tween 80®)

Experientia, 1967
Polysorbate 80 (Tween 80®), eine polyhydroxyle, nicht-ionisierbare, oberflachenaktive Substanz, vermindert die Adsorption von Urokinase an Glas, erhoht deren fibrinolytische Aktivitat in vitro und steigert ihre thrombolytische Wirkung in experimentell hervorgerufenen Thrombosen im Kaninchen.
H C, Kwaan, P, Brakman, T, Astrup
openaire   +2 more sources

The versatility of polysorbate 80 (tween 80) as an ionophore

Journal of Pharmaceutical Sciences, 1999
A number of experiments were performed to illustrate the unusual versatility of Polysorbate 80 (Tween 80) as an ionophore. New ions shown to be transported by it from and to water layers through a model membrane (CH2Cl2) include H3O+, Li+, Pb2+, Co2+, piperidinium ion, guanidinium ion, and Paraquat, while two complex ions resisted transport under the ...
openaire   +2 more sources

Effect of Tween 80 on lipid vesicle permeability

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1983
As part of an examination of procedures for protein/lipid reconstitution we incubated solubilized cytochrome oxidase at different temperatures with preformed vesicles composed of saturated lipids. We observed that the 22Na permeability of these vesicles was increased following such an incubation step, with the maximal effect occurring following ...
M, Young, M, Dinda, M, Singer
openaire   +2 more sources