Results 11 to 20 of about 376 (138)

Continuous Melt Granulation for Taste-Masking of Ibuprofen

Pharmaceutics, 2021
Taste-masking of drugs, particularly to produce formulations for pediatric patients, can be challenging and require complex manufacturing approaches. The objective of this study was to produce taste-masked ibuprofen granules using a novel process, twin ...
Seth P. Forster, David B. Lebo
doaj   +1 more source

Twin-screw melt granulation for high-dose paracetamol tablets

RPS Pharmacy and Pharmacology Reports, 2023
Abstract Objectives In this study twin-screw melt granulation (TSMG) was used to produce sustained release formulations and improve the poor compressibility of paracetamol (PMOL). Methods By using various amounts of polyethylene ...
Steven A Ross, Md Sadeque Mithu, Dennis Douroumis   +2 more
openaire   +1 more source

How Does the Dissimilarity of Screw Geometry Impact Twin-screw Melt Granulation?

European Journal of Pharmaceutical Sciences, 2021
Using a model formulation of 80% gabapentin and 20% hydroxypropyl cellulose (KlucelTM), we investigate how differences in the geometry of mixing elements in the Leistritz Nano-16 and Micro-18 extruders affect granulation mechanisms and the properties of the resulting granules.
Nada Kittikunakorn, Shubhajit Paul, John J Koleng, Tongzhou Liu, Rachel Cook, Fengyuan Yang, Vivian Bi, Thomas Durig, Changquan Calvin Sun, Aditya Kumar, Feng Zhang   +10 more
openaire   +2 more sources

Downstream processing from melt granulation towards tablets: In-depth analysis of a continuous twin-screw melt granulation process using polymeric binders [PDF]

European Journal of Pharmaceutics and Biopharmaceutics, 2018
The concept of twin-screw melt granulation (TSMG) has steadily (re)-gained interest in pharmaceutical formulation development as an intermediate step during tablet manufacturing. However, to be considered as a viable processing option for solid oral dosage forms there is a need to understand all critical sources of variability which could affect this ...
Grymonpré, Wouter, Verstraete, Glenn, Vanhoorne, Valérie, Remon, Jean Paul, De Beer, Thomas, Vervaet, Chris   +5 more
openaire   +3 more sources

Preparation and Study the Physical, Mechanical and Antimicrobial Properties of Polyethylene/Polylactic Acid Nanocomposite Films Reinforced with Nano-graphene Oxide [PDF]

مجله پژوهش‌های علوم و صنایع غذایی ایران
IntroductionPackaging is an intermediary between the produced food products and the customer, which maintains the quality of the product and provides the information required by the customer.
Maryam Fathifar, Nasser Sedaghat, Mohammad Reza Abdollahi Moghadam   +2 more
doaj   +1 more source

Continuous twin-screw melt granulation of drug-loaded electrospun fibers

European Journal of Pharmaceutics and Biopharmaceutics
Electrospinning (ES) is a promising continuous formulation strategy to produce amorphous solid dispersions (ASDs) and thereby improve the dissolution of poorly water-soluble drugs. However, processing the electrospun material into solid dosage forms (e.g. tablets) is challenging due to the poor flow properties.
Petra, Záhonyi, Áron Gábor, Müncz, Anna, Péter-Haraszti, Zsombor Kristóf, Nagy, István, Csontos, György, Marosi, Edina, Szabó   +6 more
openaire   +2 more sources

Multi‐Material Additive Manufacturing of Soft Robotic Systems: A Comprehensive Review

Advanced Robotics Research, EarlyView.
This review explores the transformative role of multi‐material additive manufacturing (MMAM) in the development of soft robotic systems. It presents current techniques, materials, and design strategies that enable functionally graded and adaptive structures.
Ritik Raj, Quan‐Chen Song, Jia‐Yang Juang   +2 more
wiley   +1 more source

Comprehensive review on modern techniques of granulation in pharmaceutical solid dosage forms

Intelligent Pharmacy
This comprehensive review explores modern granulation techniques in pharmaceutical dosage forms along with conventional methods, focusing on dry granulation and wet granulation.
Anil Kumar Vadaga, Sai Shashank Gudla, Gnanendra Sai Kumar Nareboina, Hymavathi Gubbala, Bhuvaneswari Golla   +4 more
doaj   +1 more source

Scaling of Planar Sodium‐Nickel Chloride Battery Cells to 90 cm2 Active Area

Batteries &Supercaps, Volume 8, Issue 3, March 2025.
Large planar Na β′′ alumina electrolytes are prepared by tape‐casting and die‐pressing. These ceramic electrolytes are used to prepare planar sodium‐nickel chloride cells with 90 cm2 active area, providing a high capacity of 7 Ah. Successful cell cycling is demonstrated at 300 °C at rates up to C/4 (20 mA cm−2) for a cumulative capacity of 3.6 Ah cm−2.
T. Lan, E. Svaluto‐Ferro, N. Kovalska, G. Graeber, F. Vagliani, D. Basso, A. Turconi, M. Makowska, G. Blugan, C. Battaglia, M. V. F. Heinz   +10 more
wiley   +1 more source

3D‐Printed Models in Oral Surgery Simulation Training: A Scoping Review

Journal of Dental Education, EarlyView.
ABSTRACT Background Advancements in three‐dimensional (3D) printing have introduced innovative tools for medical and dental education. In dental surgery, 3D‐printed simulation models offer valuable presurgical training. This review explores the scope, study types, key findings, limitations, and future research needs to enhance their application in ...
Shahrzad Rahimizadeh Nahavandi, Leila Gholami, Amir Parham Pirhadi Rad, Morteza Ghojazadeh, Kevin Aminzadeh, Rana Tarzemany   +5 more
wiley   +1 more source