Results 41 to 50 of about 376 (138)

Impact of hydrophilic binders on stability of lipid-based sustained release matrices of quetiapine fumarate by the continuous twin screw melt granulation technique. [PDF]

Adv Powder Technol, 2021
Nyavanandi D, Kallakunta VR, Sarabu S, Butreddy A, Narala S, Bandari S, Repka MA.   +6 more
europepmc   +1 more source

Continuous, simultaneous cocrystallization and formulation of Theophylline and 4-Aminobenzoic acid pharmaceutical cocrystals using twin screw melt granulation

European Journal of Pharmaceutical Sciences, 2019
In this work a cocrystal of Theophylline and 4Aminobenzoic acid was successfully produced and formulated using a hydrophilic binder with a novel continuous melt granulation approach. This melt granulation was followed with direct compression to generate oral solid dosage forms. The study revealed that the processing temperature, molecular weight of the
Rahamatullah, Shaikh, Gavin M, Walker, Denise M, Croker   +2 more
openaire   +2 more sources

Formulation and Evaluation of Immediate-Release Quetiapine Fumarate Tablets Via Twin-Screw Melt Granulation

Journal of Pharmaceutical Innovation
Abstract Purpose This study aimed to develop immediate-release Quetiapine Fumarate (QTF) tablets using twin-screw melt granulation (TSMG), a solvent-free and efficient granulation method, and compare their dissolution profiles with the marketed product. Methods QTF tablets
Salonee Chavan, Siva Ram Munnangi, Nagarjuna Narala, Sateesh Kumar Vemula, Michael Repka   +4 more
openaire   +1 more source

Degradation of Polypropylene and Polypropylene Compounds on Co-Rotating Twin-Screw Extruders. [PDF]

Polymers (Basel)
Albrecht P, Altepeter M, Brüning F.
europepmc   +1 more source

Double action of HPMCAS as a dry binder and precipitation inhibitor in ASD tablet formulations of nifedipine prepared by hot-melt extrusion. [PDF]

Int J Pharm X
Nakhla DS, Mishra SM, Lübbert C, Mejia L, Agatovure K, Sauer A.   +5 more
europepmc   +1 more source

Material-Preserving Extrusion of Polyamide on a Twin-Screw Extruder. [PDF]

Polymers (Basel), 2023
Schall C, Altepeter M, Schöppner V, Wanke S, Kley M.   +4 more
europepmc   +1 more source

AI-driven pilot platforms and computational pharmaceutics: accelerating innovation in small molecule drug development under industry 4.0 and 5.0 paradigms. [PDF]

Front Pharmacol
Luo K, Yang Y, Chachar S, Zhong C, Chen M, Xiong J, He L, Liu D, Baloch SK, Elshoura I, Chachar Z, Cai Y, Huang F.   +12 more
europepmc   +1 more source

Dry Amorphization of Itraconazole Using Mesoporous Silica and Twin-Screw Technology. [PDF]

Pharmaceutics
Richter M, Welzmiller S, Monsuur F, Völp AR, Quadflieg J.   +4 more
europepmc   +1 more source

Development of a Polyolefin Elastomer Modified Hybrid Inorganic Filler System for Enhanced Performance in HDPE Double-Wall Corrugated Pipe Production. [PDF]

Polymers (Basel)
Unal MA, Sungur Bastug A, Yigit Ates E, Selcuk C, Ak NN, Mutlu RT, Sucuoglu HS, Kaya B.   +7 more
europepmc   +1 more source

Fast-Track Crystallization of PB‑1 with Sorbitol-Based Nucleating Agent. [PDF]

ACS Omega
Navratilova J, Gajzlerova L, Cermak R, Polaskova M.   +3 more
europepmc   +1 more source