Predicting Pharmaceutical Particle Size Distributions Using Kernel Mean Embedding. [PDF]
Pharmaceutics, 2020 In the pharmaceutical industry, the transition to continuous manufacturing of solid dosage forms is adopted by more and more companies. For these continuous processes, high-quality process models are needed.
Van Hauwermeiren D +3 more
europepmc +3 more sources
Evaluation of Process Parameters for Continuous Manufacturing of Quetiapine Fumarate Immediate Release Tablets Using Twin Screw Wet Granulation. [PDF]
Pharm ResGranulation is one of the important unit operations in the manufacturing of solid dosage forms like tablets and capsules that regulate the quality of end products.
Naguboyina T +4 more
europepmc +3 more sources
Soft sensor for content prediction in an integrated continuous pharmaceutical formulation line based on the residence time distribution of unit operations [PDF]
, 2022 In this study, a concentration predicting soft sensor was achieved based on the Residence Time Distribution (RTD) of an integrated, three-step pharmaceutical formulation line.
Domokos, András +8 more
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Continuous twin-screw melt granulation of poorly compressible and thermal labile drug [PDF]
, 2021 Continuous twin-screw melt granulation (TSMG) has been widely used for the last 50 years in various industrial processes. For pharmaceutical manufacturing, TSMG offers many advantages over continuous twin-screw wet granulation and roller compaction ...
Kittikunakorn, Nada
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CONTINUOUS MELT GRANULATION FOR TASTE-MASKING OF ACTIVE PHARMACEUTICAL INGREDIENTS [PDF]
, 2021 Melt granulation is a versatile process that is underutilized in the pharmaceutical industry. Most pharmaceutical wet granulation and twin-screw extruders can be adapted for melt granulation.
0000-0001-6072-1959, Forster, Seth
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Twin-screw Melt Granulation as alternative Granulation Strategy [PDF]
, 2021 Melt granulation is an interesting alternative technique to produce both, immediate and controlled-release final products using twin-screw extruders. The aim of this current work was to gain a deeper understanding of the granule’s characteristic obtained
Steffens, Kristina Elena
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Downstream processing from melt granulation towards tablets : in-depth analysis of a continuous twin-screw melt granulation process using polymeric binders [PDF]
, 2018 The concept of twin-screw melt granulation (TSMG) has steadily (re)-gained interest in pharmaceutical formulation development as an intermediate step during tablet manufacturing.
De Beer, Thomas +5 more
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SCALE-UP OF PHARMACEUTICAL TWIN-SCREW WET GRANULATION BASED ON THE PROCESS SIMULATION USING GENETIC PROGRAMMING [PDF]
, 2023 Wet granulation is a crucial process in the manufacturing of pharmaceutical tablets. For several years, twin-screw wet granulation has been noticeably studied as a continuous method for granulation in the pharmaceutical industry because of its ability ...
Mozumder, Sumon
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Continuous Manufacturing of Homogeneous Ultralow-Dose Granules by Twin-Screw Wet Granulation [PDF]
, 2020 Homogeneous ultralow-dose (30 mg) tablets were prepared from perfectly free-flowing granules manufactured by continuous Twin-Screw Wet Granulation.
Balogh, Attila +14 more
core +1 more source
Formulaation ja prosessiparametrien vaikutus märkärakeiden jäännöskosteuteen jatkuvatoimisessa valmistuksessa [PDF]
, 2021 Lääketeollisuus on kiinnostunut jatkuvatoimisesta lääkkeiden tuotantotavasta sen useiden etujen vuoksi verrattuna eräkohtaiseen valmistukseen. Kaksoisruuvirakeistus (engl.
Jormanainen, Miika
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