Results 171 to 180 of about 29,018 (198)

TNFSF14-HVEM/LTβR Exacerbates Keratinocyte Abnormalities and IMQ-Induced Psoriatic Skin Inflammation via Activating NF-κB/TWIST1 Signalling Pathway. [PDF]

J Cell Mol Med
Long SJ, Zheng QY, Xu F, Li GQ, Chen J, Chen WJ, Xu JM, Gao XL, Liang SJ, Xu GL.   +9 more
europepmc   +1 more source

Radiation-Induced EMT of Adipose-Derived Stem Cells in 3D Organotypic Culture via Notch Signaling Pathway. [PDF]

Biology (Basel)
Choi SJ, Kim M, Chung KT, Son TG.
europepmc   +1 more source

Role of the RBMS Family in Different Cancers and Research Progress. [PDF]

Int J Med Sci
Wu H, Hou R, Zhang Y, Fan H, Xu J, Wang H.   +5 more
europepmc   +1 more source

Twist1-Induced Invadopodia Formation Promotes Tumor Metastasis [PDF]

Cancer Cell, 2011
The Twist1 transcription factor is known to promote tumor metastasis and induce Epithelial-Mesenchymal Transition (EMT). Here, we report that Twist1 is capable of promoting the formation of invadopodia, specialized membrane protrusions for extracellular matrix degradation.
Mark A Eckert, Jihoon Kim, Lucila Ohno-Machado   +2 more
exaly   +3 more sources

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TWIST1 upregulates the MAGEA4 oncogene

Molecular Carcinogenesis, 2016
Overexpression of MAGEA4 oncogene has been demonstrated in different malignancies; however, little is known about its exact mechanism for overexpression. TWIST1, as a bHLH transcription factor, activates a cell migration‐invasion program involved in both embryonic and tumor development. Since MAGEA4 overexpression was statistically correlated to TWIST1,
Mohammad Mahdi, Forghanifard, Abolfazl, Rad, Moein, Farshchian, Maryam, Khaleghizadeh, Mehran, Gholamin, Meysam, Moghbeli, Mohammad Reza, Abbaszadegan   +6 more
openaire   +2 more sources

Twist1 promotes dendritic cell-mediated antitumor immunity

Experimental Cell Research, 2020
Dendritic cells (DCs) play a central role in autoimmunity, immune homeostasis, and presentation of tumor antigens to T cells in order to prime antitumor responses. The number of tumor-infiltrating DCs is associated with survival and prognosis in cancer.
Yuechen, Luo, Jiadi, Chen, Maolan, Liu, Song, Chen, Xiuhua, Su, Jing, Su, Chunxiao, Zhao, Zhongchao, Han, Mingxia, Shi, Xiaotong, Ma, Huifang, Huang   +10 more
openaire   +2 more sources

Targeting epithelial cell-derived TWIST1 alleviates allergic asthma

Cellular Signalling, 2023
It is well known that the T Helper (Th)2 bias plays a critical role in allergic asthma. Whereas the Th2 bias is maintained in the local tissues is uncertain. IL-33 is vital for the development of the Th2 polarization. TWIST-1 has an effect on regulating cellular functions. The aberrant activation of RAS sustains certain cellular activities.
Huanping, Zhang, Yanfen, Wang, Xiaoxue, Chen, Aizhi, Zhang, Lijun, Hou, Jingyi, Hong, Jiangqi, Liu, Zhiqiang, Liu, Pingchang, Yang   +8 more
openaire   +2 more sources

RAC1 activation mediates Twist1-induced cancer cell migration

Nature Cell Biology, 2012
Epithelial-mesenchymal transition (EMT), which is characterized by the suppression of the adhesion protein E-cadherin, is a crucial process that promotes metastasis and stem-like properties of cancer cells. However, the dissociation of cellular aggregates is not sufficient to explain why cancer cells move, and the motile nature of cancer cells ...
Wen-Hao, Yang, Hsin-Yi, Lan, Chi-Hung, Huang, Shyh-Kuan, Tai, Cheng-Hwai, Tzeng, Shou-Yen, Kao, Kou-Juey, Wu, Mien-Chie, Hung, Muh-Hwa, Yang   +8 more
openaire   +2 more sources