Results 11 to 20 of about 1,355,661 (262)
Microbiology Spectrum, 2022 Cephalosporins are important beta lactam antibiotics, but resistance can be mediated by various mechanisms including production of beta lactamase enzymes, changes in membrane permeability or active efflux.
Eleftheria Trampari +5 more
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Systematic Reconstruction of the Complete Two-Component Sensorial Network in
mSystems, 2020 In bacteria, adaptation to changes in the environment is mainly controlled through two-component signal transduction systems (TCSs). Most bacteria contain dozens of TCSs, each of them responsible for sensing a different range of signals and controlling ...
B. Rapun-Araiz +6 more
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Frontiers in Microbiology, 2022 Colistin is the last line of defense for the treatment of multidrug-resistant gram-negative bacterial infections. However, colistin resistance is gradually increasing worldwide, with resistance commonly regulated by two-component system and mcr gene ...
Fulei Li +11 more
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The Transcriptional Regulatory Network of Corynebacterium pseudotuberculosis
Microorganisms, 2021 Corynebacterium pseudotuberculosis is a Gram-positive, facultative intracellular, pathogenic bacterium that infects several different hosts, yielding serious economic losses in livestock farming.
Doglas Parise +8 more
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A small protein that mediates the activation of a two‐component system by another two‐component system [PDF]
The EMBO Journal, 2000 The PmrA-PmrB two-component system of Salmonella enterica controls resistance to the peptide antibiotic polymyxin B and to several antimicrobial proteins from human neutrophils. Transcription of PmrA-activated genes is induced by high iron, but can also be promoted by growth in low magnesium in a process that requires another two-component system, PhoP-
L F, Kox, M M, Wösten, E A, Groisman
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Frontiers in Microbiology, 2020 Two-component systems (TCSs) are central to the ability of Mycobacterium tuberculosis to respond to stress. One such paired TCS is SenX3-RegX3, which responds to phosphate starvation. Here we show that RegX3 is required for M.
Amar Chandra Mahatha +6 more
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Evolution towards Virulence in a
mBio, 2021 Bacteria in the Burkholderia cepacia complex (BCC) are significant pathogens for people with cystic fibrosis (CF) and are often extensively antibiotic resistant.
Matthew M. Schaefers +8 more
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Drug inhibition of bacterial two-component regulatory systems
Zdorovʹe Rebenka, 2018 There are several ways to adapt and increase the chances of survival of microorganisms. Specific systems involved in the recognition of external changes and the organization of the corresponding reaction of the microorganism are called bacterial sensory ...
А.Е. Abaturov, Т.А. Kryuchko
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Frontiers in Microbiology, 2019 Acinetobacter baumannii is a notorious pathogen in health care settings around the world, primarily due to high resistance to antibiotics. A. baumannii also shows an impressive capability to adapt to harsh conditions in clinical settings, which ...
P. Malaka De Silva +2 more
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Environmental Triggers of lrgA Expression in Streptococcus mutans
Frontiers in Microbiology, 2020 The cidAB and lrgAB operons of Streptococcus mutans encode proteins that are structurally similar to the bacteriophage lambda family of holin-antiholin proteins, which are believed to facilitate cell death in other bacterial species.
Ivan P. Ishkov +3 more
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