Results 71 to 80 of about 373,972 (292)

Dynamic panel regression with fuzzy outputs: A two-stage estimation framework

Systems and Soft Computing
Traditional panel data models, while effective in managing longitudinal and cross-sectional variations, are not suitable for handling imprecise data in real-world scenarios caused by vagueness, subjectivity or measurement limitations.
Gholamreza Hesamian, Arne Johannssen
doaj   +1 more source

Inference for Two-Stage Extremum Estimators

SSRN Electronic Journal
We present a simulation-based inference approach for two-stage estimators, focusing on extremum estimators in the second stage. We accommodate a broad range of first-stage estimators, including extremum estimators, high-dimensional estimators, and other types of estimators such as Bayesian estimators.
Houndetoungan, Aristide, Maoude, Abdoul Haki   +1 more
openaire   +2 more sources

Estimating Reference Ranges from Stratified Two-stage Samples

Journal of the Royal Statistical Society Series A: Statistics in Society, 2001
Summary We present methodology for estimating age-specific reference ranges by using data from two-stage samples. On the basis of the information obtained in the first stage, the initial sample is stratified and random subsamples are drawn from each stratum, where the selection probabilities in this second-stage sampling may be different
Thompson, Mary Lou, Edland, Steven D., Gibbons, Laura E., McCurry, Susan M.   +3 more
openaire   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

MRIE: Enhanced Rainfall Intensity Estimation With Two-Stage Multimodal Deep Learning

IEEE Access
Accurate rainfall intensity estimation is crucial for environmental monitoring and urban planning. However, the reliability of existing methods in practical applications is relatively low due to certain deficiencies in data processing and noise ...
Jin Li, Wentao Hu, Zhigang Zhou
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Two-Stage Kalman Filter for Fault Tolerant Estimation of Wind Speed and UAV Flight Parameters

Measurement Science Review, 2020
In this study, an estimation algorithm based on a two-stage Kalman filter (TSKF) was developed for wind speed and Unmanned Aerial Vehicle (UAV) motion parameters. In the first stage, the wind speed estimation algorithm is used with the help of the Global
Hajiyev Chingiz, Cilden-Guler Demet, Hacizade Ulviye   +2 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source