Results 91 to 100 of about 1,005,829 (270)

Optimizing energy flow in advanced microgrids: a prediction-independent two-stage hybrid system approach

Energy Informatics
This paper presents a two-stage optimization framework for long-term energy management in microgrids, aiming to efficiently integrate various energy sources, storage systems, and consumption elements while addressing uncertainties in load demand and ...
Mohamad Javad Mohamadi, Mohammad Tolou Askari, Mahmoud Samiei Moghaddam, Vahid Ghods   +3 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Quasi-single-stage optimization for permanent magnet stellarators

Nuclear Fusion
Advanced stellarators are typically optimized in two stages. The plasma equilibrium is optimized first, followed by the design of coils/permanent magnets.
Guodong Yu, Ke Liu, Tianyi Qian, Yidong Xie, Xianyi Nie, Caoxiang Zhu   +5 more
doaj   +1 more source

An Aggregated Optimization Model for Multi-Head SMD Placements [PDF]

In this article we propose an aggregate optimization approach by formulating the multi-head SMD placement optimization problem into a mixed integer program (MIP) with the variables based on batches of components.
Ashayeri, J., Ma, N., Sotirov, R.
core   +1 more source

Analysis and Optimization of Synthetic Aperture Ultrasound Imaging Using the Effective Aperture Approach [PDF]

, 2005
An effective aperture approach is used as a tool for analysis and parameter optimization of mostly known ultrasound imaging systems - phased array systems, compounding systems and synthetic aperture imaging systems.
Behar, Vera, Nikolov, Milen
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

An optimized two stage U-Net approach for segmentation of pancreas and pancreatic tumor

MethodsX
The segmentation of pancreas and pancreatic tumor remain a persistent challenge for radiologists. Consequently, it is essential to develop automated segmentation methods to address this task.
Himali Ghorpade, Shrikrishna Kolhar, Jayant Jagtap, Jayasree Chakraborty   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A Two-Stage Optimization Approach for Healthcare Facility Location- Allocation Problems With Service Delivering Based on Genetic Algorithm. [PDF]

Int J Public Health, 2023
Salami A, Afshar-Nadjafi B, Amiri M.
europepmc   +1 more source