Results 91 to 100 of about 1,008,660 (269)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Optimizing energy flow in advanced microgrids: a prediction-independent two-stage hybrid system approach

Energy Informatics
This paper presents a two-stage optimization framework for long-term energy management in microgrids, aiming to efficiently integrate various energy sources, storage systems, and consumption elements while addressing uncertainties in load demand and ...
Mohamad Javad Mohamadi, Mohammad Tolou Askari, Mahmoud Samiei Moghaddam, Vahid Ghods   +3 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Quasi-single-stage optimization for permanent magnet stellarators

Nuclear Fusion
Advanced stellarators are typically optimized in two stages. The plasma equilibrium is optimized first, followed by the design of coils/permanent magnets.
Guodong Yu, Ke Liu, Tianyi Qian, Yidong Xie, Xianyi Nie, Caoxiang Zhu   +5 more
doaj   +1 more source

Incremental evolution strategy for function optimization [PDF]

, 2006
This paper presents a novel evolutionary approach for function optimization Incremental Evolution Strategy (IES). Two strategies are proposed. One is to evolve the input variables incrementally.
Guan, SU, Mo, W
core  

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

An optimized two stage U-Net approach for segmentation of pancreas and pancreatic tumor

MethodsX
The segmentation of pancreas and pancreatic tumor remain a persistent challenge for radiologists. Consequently, it is essential to develop automated segmentation methods to address this task.
Himali Ghorpade, Shrikrishna Kolhar, Jayant Jagtap, Jayasree Chakraborty   +3 more
doaj   +1 more source

An Aggregated Optimization Model for Multi-Head SMD Placements [PDF]

In this article we propose an aggregate optimization approach by formulating the multi-head SMD placement optimization problem into a mixed integer program (MIP) with the variables based on batches of components.
Ashayeri, J., Ma, N., Sotirov, R.
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

A Two-Stage Optimization Approach for Healthcare Facility Location- Allocation Problems With Service Delivering Based on Genetic Algorithm. [PDF]

Int J Public Health, 2023
Salami A, Afshar-Nadjafi B, Amiri M.
europepmc   +1 more source