The osmoregulated metabolism of trehalose contributes to production of type 1 fimbriae and bladder colonization by extraintestinal Escherichia coli strain BEN2908 [PDF]
In Escherichia coli, the disaccharide trehalose can be metabolized as a carbon source or be accumulated as an osmoprotectant under osmotic stress. In hypertonic environments, E. coli accumulates trehalose in the cell by synthesis from glucose mediated by
Vivian Souza Klemberg +8 more
doaj +2 more sources
Identification of OxyR as an activator of type 1 fimbriae (fim) in Salmonella enterica serovar Typhi [PDF]
Salmonella enterica serovar Typhi (S. Typhi) encodes 14 fimbrial gene clusters, including the mannose-binding type 1 fimbriae known as Fim. Type 1 fimbriae have been implicated in biofilm formation and adhesion to host cells in Salmonella. However, their
Karine Dufresne +4 more
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Strain and host-cell dependent role of type-1 fimbriae in the adherence phenotype of super-shed Escherichia coli O157:H7 [PDF]
Super-shed (SS) Escherichia coli O157 (E. coli O157) demonstrate a strong, aggregative, locus of enterocyte effacement (LEE)-independent adherence phenotype on bovine recto-anal junction squamous epithelial (RSE) cells, and harbor polymorphisms in non ...
Robab Katani +10 more
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RstAB activates type 1 fimbriae to promote uropathogenic Escherichia coli bladder invasion [PDF]
Summary: Urinary tract infections (UTIs), primarily caused by uropathogenic Escherichia coli (UPEC), are a significant public health problem. UPEC relies on type 1 fimbria to invade bladder epithelial cells (BECs), which is a crucial step in the ...
Qian Wang +10 more
doaj +2 more sources
Lrp acts as both a positive and negative regulator for type 1 fimbriae production in Salmonella enterica serovar Typhimurium. [PDF]
Leucine-responsive regulatory protein (Lrp) is known to be an indirect activator of type 1 fimbriae synthesis in Salmonella enterica serovar Typhimurium via direct regulation of FimZ, a direct positive regulator for type 1 fimbriae production.
Chang-Ho Baek +3 more
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Engineering and Evaluation of a Live-Attenuated Vaccine Candidate with Enhanced Type 1 Fimbriae Expression to Optimize Protection Against Salmonella Typhimurium [PDF]
Background:Salmonella Typhimurium is a major zoonotic pathogen, in which type 1 fimbriae play a crucial role in intestinal colonization and immune modulation.
Patricia García +7 more
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Biofilm formation by Klebsiella pneumoniae on indwelling medical devices increases the risk of infection. Both type 1 and type 3 fimbriae are important factors in biofilm formation by K. pneumoniae. We found that a putative enzyme II (EII) complex of the
Novaria Sari Dewi Panjaitan +2 more
exaly +3 more sources
A previously uncharacterized gene
Background Salmonella enterica serotype Typhimurium produces surface-associated fimbriae that facilitate adherence of the bacteria to a variety of cells and tissues. Type 1 fimbriae with binding specificity to mannose residues are the most commonly found
Wang Ke-Chuan +3 more
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Arginine within a specific motif near the N‐terminal of FimY is critical for the maximal production of type 1 fimbriae in Salmonella enterica serovar Typhimurium [PDF]
An important Salmonella serovar for both human and animals Salmonella Typhimurium possesses 13 gene clusters that have the potential to produce fimbrial structure, among which the type 1 fimbriae with the binding specificity to mannose residue is the ...
Nan‐Ling Kuan, Kuang‐Sheng Yeh
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Structure, Function, and Assembly of Type 1 Fimbriae
Bacterial infections constitute a major global health problem, acutely accentuated by the rapid spread of antibiotic resistant bacterial strains. The widespread need for bacteria to attach - adhere - to target cells before they can initiate an infection may be used to advantage by targeting the bacterial adhesion tools such as pili and fimbriae for ...
Stefan D, Knight, Julie, Bouckaert
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