Results 91 to 100 of about 1,627,676 (310)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Moderate alcohol consumption, adiponectin, inflammation and type 2 diabetes risk : prospective cohort studies and randomized crossover trials [PDF]

, 2010
Background: Moderate alcohol consumption has been associated with a lower risk of type 2 diabetes in various populations. However, the underlying mechanisms are not entirely clear.
Joosten, M.M.
core  

Trends in the prevalence and management of diagnosed type 2 diabetes 1994-2001 in England and Wales. [PDF]

, 2005
BACKGROUND: Type 2 diabetes is an important cause of morbidity and mortality. Its prevalence appears to be increasing. Guidelines exist regarding its management. Recommendations regarding drug therapy have changed.
Sismanidis, Charalambos, Nicky Richards, Lusignan, S, Lusignan, Simon, Derek G Cook, DeWilde, Stephen, DeWilde Stephen, Iain M Carey, Stephen DeWilde, Carey Iain M, Simon de Lusignan, Cook, Derek G, Charalambos Sismanidis, Cook Derek G, Richards, N, de Lusignan Simon, DeWilde, S, Sismanidis, C, Carey, IM, Richards, Nicky, Sismanidis Charalambos, Richards Nicky, Cook, DG, Carey, Iain M   +23 more
core   +1 more source

Bromocriptine in type 2 diabetes mellitus

Indian Journal of Endocrinology and Metabolism, 2011
Bromocriptine mesylate quick-release was approved by the Food and Drug Administration (FDA) in May 2009, for the treatment of type 2 diabetes. Bromocriptine is thought to act on the circadian neuronal activities in the hypothalamus, to reset an ...
C Shivaprasad, Sanjay Kalra
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

The prevalence of Type 2 diabetes and its associated health problems in a community-dwelling elderly population. [PDF]

, 2009
AIMS: Prevalence estimates of Type 2 diabetes and its associated health problems in elderly populations are rare, especially in the very elderly. METHODS: A sample of 15 095 community-dwelling older people aged > or = 75 years were assessed.
Fletcher, AE, Fletcher, A. E., Hewitt, J, Smeeth, L, Smeeth, L., Hewitt, J., Bulpitt, CJ, Bulpitt, C. J.   +7 more
core   +1 more source

Sleep disorders in type 2 diabetes

Indian Journal of Endocrinology and Metabolism, 2017
Type 2 diabetes mellitus (T2DM) has shown to be associated with higher incidence of sleep disorders, which may be due to disease itself or because of secondary complications or associated comorbidities associated with diabetes. On the other hand, shorter
Deepak Khandelwal, Deep Dutta, Sachin Chittawar, Sanjay Kalra   +3 more
doaj   +1 more source

Magnesium and type 2 diabetes

World Journal of Diabetes, 2015
Type 2 diabetes is frequently associated with both extracellular and intracellular magnesium (Mg) deficits. A chronic latent Mg deficit or an overt clinical hypomagnesemia is common in patients with type 2 diabetes, especially in those with poorly controlled glycemic profiles. Insulin and glucose are important regulators of Mg metabolism. Intracellular
Barbagallo, M., Dominguez Rodriguez, L.J.   +1 more
openaire   +3 more sources

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Self monitoring of blood glucose : a survey of diabetes UK members with type 2 diabetes who use SMBG [PDF]

, 2010
Background Aim - to survey members of Diabetes UK who had Type 2 diabetes and who used self monitoring of blood glucose (SMBG), to elicit their views on its usefulness in the management of their diabetes, and how they used the results.
Barnard Katharine D, Barnard, Katharine D., Waugh, Norman, Norman R Waugh, Barnard, Katharine D, Young Amanda J, Waugh, Norman R, Young, Amanda J., Amanda J Young, Young, Amanda J, Waugh Norman R, Katharine D Barnard   +11 more
core   +1 more source