Results 81 to 90 of about 31,218,454 (304)

Postprandial Dysmetabolism and Non-Alcoholic Fatty Liver Disease in Relation to Type 2 Diabetes Mellitus and Cardiovascular Risk [PDF]

, 2007
Het aantal gevallen van “ouderdomssuikerziekte” (type 2 diabetes mellitus) neemt in de Westerse wereld snel toe als gevolg van veranderingen in leefstijl (verhoogde consumptie van vet- en energierijke voeding en verminderde lichaamsbeweging), en als ...
Schindhelm, R.K.
core   +5 more sources

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

HYPERTENSION AND DIABETES MELLITUS TYPE 2

Рациональная фармакотерапия в кардиологии, 2018
Aim. To study the effect of long-term combined antihypertensive therapy with lisinopril plus amlodipine on the parameters of central aortic pressure (CAD) and visceral obesity in patients with arterial hypertension (HT) combined with type 2 diabetes ...
M. E. Statsenko, M. V. Derevyanchenko
doaj   +1 more source

Diabetic retinopathy at diagnosis of type 2 diabetes in Scotland [PDF]

, 2012
The prevalence of retinopathy at first screening is lower than in previous UK studies, consistent with earlier diagnosis of diabetes. Most newly diagnosed type 2 diabetic patients in Scotland are screened within an acceptable interval and the prevalence ...
Lee, N, Colhoun, H.M., H. C. Looker, Colhoun, H. M., M. Black, Sattar, N, Olson, J.A., Morris, A D, Olson, J. A., Philip, Sam, J. A. Olson, S. H. Wild, Olson, J A, Black, M., S. O. Nyangoma, Leese, G P, Doig, J, H. M. Colhoun, Looker, H C, Doig, J., ?, ?, J. A. McKnight, Nyangoma, S. O., Lindsay, R. S., null null, Nyangoma, S O, Lindsay, R S, Colhoun, H M, McKnight, J A, Leese, G.P., Black, M, Wild, S H, D. Cromie, Sattar, N., Cromie, D., Wild, S.H., A. D. Morris, Scottish Diabetic Retinopathy Screening Collaborative, McKnight, J. A., Morris, A.D., Lindsay, R.S., Leese, G. P., Morris, Andrew, Lee, N., G. P. Leese, N. Sattar, N. Lee, Cromie, D, Wild, S. H.; id_orcid, Looker, H. C., R. S. Lindsay, McKnight, J.A., J. Doig, Nyangoma, S.O., Philip, S., S. Philip, Looker, H.C.   +56 more
core   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Nephropathy in type 2 diabetes [PDF]

Journal of Internal Medicine, 1999
End‐stage renal failure (ESRF) in diabetic patients, mostly type 2, has become the most frequent cause of renal replacement therapy in western Europe. The majority of patients with type 2 diabetes and renal failure suffer from diabetic glomerulosclerosis, but non‐diabetic renal disease and atypical presentations, e.g.
openaire   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Validity and reliability of the DMSES UK : a measure of self-efficacy for type 2 diabetes self-management [PDF]

, 2010
Objectives Self-efficacy is an important outcome measure of self-management interventions. We aimed to establish UK validity and reliability of the diabetes management self-efficacy scale (DMSES).
Hilary Hearnshaw, Wakelin, Melanie, Jackie Sturt, Sturt, Jackie, Sturt, Jackie; id_orcid, Wakelin, M., Melanie Wakelin, Hearnshaw, Hilary   +7 more
core   +1 more source

Arrhythmias in type 2 diabetes mellitus

Indian Journal of Endocrinology and Metabolism, 2017
Chronic hyperglycaemia of Type 2 diabetes mellitus causes long term damage to heart resulting in coronary artery disease (CAD), myocardial infarction (MI), congestive heart failure (CHF), and sudden death from arrhythmias.
Gaurav Agarwal, Satish Kumar Singh
doaj   +1 more source

TREATMENT OF TYPE 2 DIABETES

Acta Clinica Belgica, 2003
Type 2 diabetes is a heterogeneous disease resulting from a dynamic interaction between defects in insulin secretion and insulin action. As most subjects are overweighted or obese, the initial treatment is optimization of the meal plan and enhancement of physical activity in order to obtain sustained weight reduction.
openaire   +2 more sources