Results 41 to 50 of about 5,664,310 (354)

The prevalence of Type 2 diabetes and its associated health problems in a community-dwelling elderly population.

, 2009
AIMS: Prevalence estimates of Type 2 diabetes and its associated health problems in elderly populations are rare, especially in the very elderly. METHODS: A sample of 15 095 community-dwelling older people aged > or = 75 years were assessed.
Bulpitt, CJ, Fletcher, AE, Hewitt, J, Smeeth, L   +3 more
core   +1 more source

Long-term glycemic variability and risk of adverse outcomes: a systematic review and meta-analysis [PDF]

, 2015
OBJECTIVE: Glycemic variability is emerging as a measure of glycemic control, which may be a reliable predictor of complications. This systematic review and meta-analysis evaluates the association between HbA1c variability and micro- and macrovascular ...
Catherine Gorst, Cavalot, Chun Shing Kwok, Evangelos Kontopantelis, Foo, Grant Heatlie, Hermann, Iain Buchan, Kontopantelis, Lin, Maciejewski, Mamas A. Mamas, Martin K. Rutter, Phyo K. Myint, Raman, Saadia Aslam, Skriver, Sperrin, Yoon Loke   +18 more
core   +1 more source

Reversal of Type 2 Diabetes Mellitus

RUHS Journal of Health Sciences, 2023
NA
Sudhir Bhandari
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

The importance of diet and exercise in preventing type 2 diabetes [PDF]

, 2014
Diabetes is reaching epidemic proportions globally with estimates of 374 million people worldwide (WHO 2014 ) and impacts on the people with the condition, their families and on health service resources.
McDowell, Joan
core  

Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population [PDF]

, 2008
Background Recent studies have implicated variants of the transcription factor 7-like 2 (TCF7L2) gene in genetic susceptibility to type 2 diabetes mellitus in several different populations. The aim of this study was to determine whether variants of this
A Helgason, Abigail C Britten, AH Barnett, Anthony H Barnett, C Zhang, CM Damcott, GR Chandak, J Paul O'Hare, J Wang, JC Barrett, JC Florez, JC Florez, JV van Vliet-Ostaptchouk, LJ Scott, M Ann Kelly, R Saxena, R Zhang, RJ Loos, S Cauchi, S Cauchi, S Mayans, SE Humphries, SF Grant, Simon D Rees, Srikanth Bellary, Sudhesh Kumar, The International HapMap Consortium, U Smith, WHO Consultation   +28 more
core   +6 more sources

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Golgi-associated retrograde protein (GARP) complex-dependent endosomes to trans Golgi network retrograde trafficking is controlled by Rab4b

Cellular & Molecular Biology Letters
Background The trafficking of cargoes from endosomes to the trans-Golgi network requires numerous sequential and coordinated steps. Cargoes are sorted into endosomal-derived carriers that are transported, tethered, and fused to the trans-Golgi network ...
Jérôme Gilleron, Abderrahman Chafik, Sandra Lacas-Gervais, Jean-François Tanti, Mireille Cormont   +4 more
doaj   +1 more source

MicroRNAs and type 2 diabetes

ExRNA, 2019
MicroRNAs (miRNAs) are non-coding single strand RNAs. MiRNAs are encoded by endogenous genes with a length of about 22 nucleotides. MiRNAs play a vital role in the inhibition of post-transcriptional translation of mRNAs.
Jiali Deng, Feifan Guo
doaj   +1 more source

The potential for deprescribing in care home residents with Type 2 diabetes [PDF]

, 2016
Background: Type 2 diabetes is a common diagnosis in care home residents that is associated with potentially inappropriate prescribing and thus risk of additional suffering.
Andreassen, Lillan Mo, Desborough, James Antony, Houghton, Julie, Kjome, Reidun Lisbet Skeide, Sølvik, Una Ørvim   +4 more
core   +1 more source