Results 61 to 70 of about 102,290,503 (289)

HOIL1 regulates group 2 innate lymphoid cell numbers and type 2 inflammation in the small intestine [PDF]

, 2022
Patients with mutations in HOIL1 experience a complex immune disorder including intestinal inflammation. To investigate the role of HOIL1 in regulating intestinal inflammation, we employed a mouse model of partial HOIL1 deficiency.
Hartley, Victoria L, MacDuff, Donna A., Wood, Matthew J., Hartley, Victoria L., Marshall, Jeffrey N, Stappenbeck, Thaddeus S, MacDuff, Donna A, Stappenbeck, Thaddeus S., Liu, Ta-Chiang, Marshall, Jeffrey N., Wood, Matthew J, Iwai, Kazuhiro, Victoria L. Hartley, Ta-Chiang Liu, Donna A. MacDuff, Thaddeus S. Stappenbeck, Kazuhiro Iwai, Matthew J. Wood, Jeffrey N. Marshall   +18 more
core   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

The impact of obesity and inflammation on metabolic risk factors for cardiovascular disease and type two diabetes in black and white South African women [PDF]

, 2011
[T]he overall aim of this thesis was to investigate the ethnic-specific role of inflammation in obesity and related metabolic risk factors associated with T2DM and CVD in apparently healthy black and white premenopausal South African ...
Evans, Juliet P
core   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

MAJOR DEPRESSIVE DISORDER, TYPE 2 DIABETES MELLITUS AND INFLAMMATION

Trakia Journal of Sciences
Inflammation may play a key role in the pathogenesis of both depression and type 2 diabetes. However, elevated levels of circulating IL-6 are an independent predictor of type 2 diabetes and are thought to occurwith the development of ...
Y.Petkov
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

A basophil-fibroblast pro-inflammatory axis fuels type 2 skin inflammation

Cell Reports
Summary: Chronic inflammatory skin diseases arise from dysregulated interactions between tissue-resident and infiltrating cells, the complexity of which hinders disease understanding and treatment.
Ichiro Imanishi, Raman Gill, Alexis Wilder, Paula Restrepo, Arjun Nair, Inchul Cho, James G. Krueger, Emma Guttman-Yassky, Brian S. Kim, Andrew L. Ji   +9 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Treatment of periodontitis reduces systemic inflammation in type 2 diabetes [PDF]

, 2020
Aims: To assess the impact of periodontal treatment on systemic inflammation in type 2 diabetes. Materials and methods: Adults with type 2 diabetes (n = 83) and without diabetes (controls, n = 75) were recruited, and participants with periodontitis ...
Al-Shahwani, Rana, Susan M. Bissett, Bikker, Jan Willem, De Jager, Marko, Preshaw, Philip M., Wassall, Rebecca R., Preshaw, Philip M.; id_orcid, De Jager, Marco, Areibi, Aisha, Rana Al‐Shahwani, Philip M. Preshaw, Wieke Selten, Aisha Areibi, Jaedicke, Katrin M., Kerry M. Whall, Rachel van de Merwe, Bissett, Susan M., Taylor, Roy, Katrin M. Jaedicke, Marko De Jager, Roy Taylor, van de Merwe, Rachel, Selten, Wieke, Rebecca R. Wassall, Jan Willem Bikker, Jolanta Weaver, Paiboon Jitprasertwong, Taylor, John J., Jaedicke, Katrin, Whall, Kerry M., Weaver, Jolanta, Jitprasertwong, Paiboon, John J. Taylor   +32 more
core   +1 more source