Results 51 to 60 of about 102,290,503 (289)

Type 2 Inflammation in Eosinophilic Esophagitis: From Pathophysiology to Therapeutic Targets

Frontiers in Physiology, 2022
Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease of the esophagus characterized clinically by symptoms related to esophageal dysfunction and histologically by eosinophil-predominant inflammation, whose incidence is rising.
Francesca Racca, Francesca Racca, Gaia Pellegatta, Giuseppe Cataldo, Edoardo Vespa, Edoardo Vespa, Elisa Carlani, Corrado Pelaia, Giovanni Paoletti, Giovanni Paoletti, Maria Rita Messina, Maria Rita Messina, Emanuele Nappi, Emanuele Nappi, Giorgio Walter Canonica, Giorgio Walter Canonica, Alessandro Repici, Alessandro Repici, Enrico Heffler, Enrico Heffler   +19 more
doaj   +1 more source

Association between traffic-related air pollution, subclinical inflammation and impaired glucose metabolism : results from the SALIA study [PDF]

, 2013
Environmental and lifestyle factors regulate the expression and release of immune mediators. It has been hypothesised that ambient air pollution may be such an external factor and that the association between air pollution and impaired glucose metabolism
Thomas Schulte (495231), Christian Herder (44905), Vierkötter, Andrea, Roden, Michael, Mohammad Vossoughi (495227), Ursula Krämer, Tom Teichert (495226), Schulte, Thomas, Tamara Schikowski, Mohammad Vossoughi, Christian Luckhaus (495232), Christian Luckhaus, Christian Herder, Ursula Krämer (163169), Tom Teichert, Luckhaus, Christian, Vossoughi, Mohammad, Tamara Schikowski (495230), Thomas Schulte, Schikowski, Tamara, Krämer, Ursula, Michael Roden (73251), Sugiri, Dorothea, Dorothea Sugiri, Dorothea Sugiri (495229), Andrea Vierkötter, Andrea Vierkötter (495228), Michael Roden, Teichert, Tom, Herder, Christian, Sugiri Dorothea, Schikowski Tamara, Teichert Tom, Roden Michael, Krämer Ursula, Schulte Thomas, Luckhaus Christian, Vierkötter Andrea, Herder Christian, Vossoughi Mohammad   +39 more
core   +2 more sources

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

352 Macrophage regulation of inflammation in type 2 diabetes

Journal of Clinical and Translational Science
Objectives/Goals: Type 2 diabetes is a metabolic disease characterized by non-resolving inflammation. Our objective is to investigate how macrophages contribute to this dysregulation.
Tanvi Banota, Valerie Horsley, Kathryn Miller-Jensen   +2 more
doaj   +1 more source

Parents of Youth With Cancer Report on Their Psychosocial Care: iSTEPPP Survey Finds Alignment and Gaps With Standards

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau, Kimberly Buff, Michele A. Scialla, Kimberly S. Canter, Lori Wiener, Victoria Sardi‐Brown, Julia B. Tager, Kamyar Arasteh, Anne E. Kazak   +8 more
wiley   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Beyond CCR7: dendritic cell migration in type 2 inflammation

Frontiers in Immunology
Conventional dendritic cells (cDCs) are crucial antigen-presenting cells that initiate and regulate T cell responses, thereby shaping immunity against pathogens, innocuous antigens, tumors, and self-antigens. The migration of cDCs from peripheral tissues
Audrey Meloun, Audrey Meloun, Beatriz León   +2 more
doaj   +1 more source

Targeting inflammation in the treatment of type 2 diabetes [PDF]

Diabetes, Obesity and Metabolism, 2013
Islets of patients with type 2 diabetes display the typical features of an inflammatory process characterized by the presence of cytokines, chemokines, immune cell infiltration, impaired function and tissue destruction with fibrotic areas.
openaire   +4 more sources

Uncovering Inequities: The Role of Social Determinants of Health in Hospitalized Adolescents and Young Adults With Heavy Menstrual Bleeding

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Heavy menstrual bleeding (HMB) is a common condition among adolescents and young adults (AYAs) and is the leading cause of iron deficiency anemia (IDA) in this population. Growing evidence suggests that social determinants of health (SDOH) influence menstrual bleeding patterns, access to care, and treatment. However, no studies have
Maria Carter‐Febres, Cristina Tarango, Ashley Childress, Chunyan Liu, Evan Thomas, Jennifer Pomales, Eric S. Mullins   +6 more
wiley   +1 more source

Type 2 inflammation and cardiometabolic disease in middle-aged adults

ERJ Open Research
Background Asthma has been associated with a higher risk for cardiometabolic disease. One possible explanation is the activation of type 2 inflammation.
Johanna Haglund, Fredrik Sundbom, Andrei Malinovschi, Christer Janson   +3 more
doaj   +1 more source