Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò +18 more
wiley +1 more source
Role of listeriolysin O and phospholipases C in <i>L. monocytogenes</i> intercellular protrusion dynamics, resolution, and autophagy avoidance. [PDF]
Fields M +6 more
europepmc +1 more source
Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu +3 more
wiley +1 more source
ARNT2 repression disrupts neuronal identity and promotes glioblastoma growth. [PDF]
Hao YH +10 more
europepmc +1 more source
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos +7 more
wiley +1 more source
Search for and functional annotation of multi-domain PLA2 family proteins in flatworms.
Bocharnikova ME +2 more
europepmc +1 more source
Comparative studies of the effects of Naja ashei venom-derived proteins on model and native lipid membranes. [PDF]
Dyba B +8 more
europepmc +1 more source
Phospholipid Networks as Metabolic Hubs and Signaling Integrators in Plant Development and Stress Adaptation. [PDF]
Chang P +10 more
europepmc +1 more source
ABSTRACT This review synthesizes current research on the phytoremediation potential of industrial hemp (Cannabis sativa L.) for heavy metals, including arsenic, aluminium, mercury, copper, lead, cadmium, nickel, and zinc, as well as per‐ and polyfluoroalkyl substances (PFAS), commonly referred to as “forever chemicals.” A structured and transparent ...
Omid Ansari, Luca De Prato
wiley +1 more source
Transcriptomic Insights Into the Evolution of Snake Venom: Mechanisms, Diversity, and Adaptation. [PDF]
Sofyantoro F +13 more
europepmc +1 more source

