Results 101 to 110 of about 1,118,779 (342)
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Harpin of Pseudomonas syringae pv. phaseolicola Harbors a Protein Binding Site
Harpin HrpZ of plant-pathogenic bacterium Pseudomonas syringae elicits a hypersensitive response (HR) in some nonhost plants, but its function in the pathogenesis process is still obscure.
Chun-Mei Li +5 more
doaj +1 more source
Pathogen-host reorganization during Chlamydia invasion revealed by cryo-electron tomography [PDF]
Invasion of host cells is a key early event during bacterial infection, but the underlying pathogen-host interactions are yet to be fully visualised in three-dimensional detail.
Hackstadt T. +6 more
core +1 more source
Type III Secretion in Root-Colonising Pseudomonas
Pseudomonads enter into intimate associations with plants that can result in either plant growth promotion or cell death and disease. Two bacteria that exemplify these different interactions are the plant pathogen Pseudomonas syringae and the plant growth-promoting rhizobacterium (PGPR) P. fluorescens. P.
Preston, G, Bertrand, N, Rainey, P
openaire +2 more sources
Regulation of type III secretion in Bordetella [PDF]
SummaryThe BvgAS virulence control system regulates the expression of type III secretion genes in Bordetella subspecies that infect humans and other mammals. We have identified five open reading frames, btrS, btrU, btrX, btrW and btrV, that are activated by BvgAS and encode regulatory factors that control type III secretion at the levels of ...
Seema, Mattoo +3 more
openaire +2 more sources
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
The hrp/wts gene cluster of Pantoea stewartii subsp. stewartii is required for pathogenicity on sweet corn and the ability to elicit a hypersensitive response (HR) in tobacco.
Reid D. Frederick +5 more
doaj +1 more source
Type III secretion: The bacteria-eukaryotic cell express [PDF]
Type III secretion (T3S) is an export pathway used by Gram-negative pathogenic bacteria to inject bacterial proteins into the cytosol of eukaryotic host cells.
Cornelis, Guy R. +2 more
core
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Transposon mutagenesis was used to isolate nonpathogenic mutants of Xanthomonas campestris pv. glycines 8ra, which causes bacterial pustule disease in soybean.
Changsik Oh +3 more
doaj +1 more source

