Results 101 to 110 of about 1,118,779 (342)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Harpin of Pseudomonas syringae pv. phaseolicola Harbors a Protein Binding Site

open access: yesMolecular Plant-Microbe Interactions, 2005
Harpin HrpZ of plant-pathogenic bacterium Pseudomonas syringae elicits a hypersensitive response (HR) in some nonhost plants, but its function in the pathogenesis process is still obscure.
Chun-Mei Li   +5 more
doaj   +1 more source

Pathogen-host reorganization during Chlamydia invasion revealed by cryo-electron tomography [PDF]

open access: yes, 2014
Invasion of host cells is a key early event during bacterial infection, but the underlying pathogen-host interactions are yet to be fully visualised in three-dimensional detail.
Hackstadt T.   +6 more
core   +1 more source

Type III Secretion in Root-Colonising Pseudomonas

open access: yes, 2001
Pseudomonads enter into intimate associations with plants that can result in either plant growth promotion or cell death and disease. Two bacteria that exemplify these different interactions are the plant pathogen Pseudomonas syringae and the plant growth-promoting rhizobacterium (PGPR) P. fluorescens. P.
Preston, G, Bertrand, N, Rainey, P
openaire   +2 more sources

Regulation of type III secretion in Bordetella [PDF]

open access: yesMolecular Microbiology, 2004
SummaryThe BvgAS virulence control system regulates the expression of type III secretion genes in Bordetella subspecies that infect humans and other mammals. We have identified five open reading frames, btrS, btrU, btrX, btrW and btrV, that are activated by BvgAS and encode regulatory factors that control type III secretion at the levels of ...
Seema, Mattoo   +3 more
openaire   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Genetic Organization of the Pantoea stewartii subsp. stewartii hrp Gene Cluster and Sequence Analysis of the hrpA, hrpC, hrpN, and wtsE Operons

open access: yesMolecular Plant-Microbe Interactions, 2001
The hrp/wts gene cluster of Pantoea stewartii subsp. stewartii is required for pathogenicity on sweet corn and the ability to elicit a hypersensitive response (HR) in tobacco.
Reid D. Frederick   +5 more
doaj   +1 more source

Type III secretion: The bacteria-eukaryotic cell express [PDF]

open access: yes, 2017
Type III secretion (T3S) is an export pathway used by Gram-negative pathogenic bacteria to inject bacterial proteins into the cytosol of eukaryotic host cells.
Cornelis, Guy R.   +2 more
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

An hrcU-Homologous Gene Mutant of Xanthomonas campestris pv. glycines 8ra That Lost Pathogenicity on the Host Plant but Was Able to Elicit the Hypersensitive Response on Nonhosts

open access: yesMolecular Plant-Microbe Interactions, 1999
Transposon mutagenesis was used to isolate nonpathogenic mutants of Xanthomonas campestris pv. glycines 8ra, which causes bacterial pustule disease in soybean.
Changsik Oh   +3 more
doaj   +1 more source

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