This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian +5 more
wiley +1 more source
Isopropyl paraben targets type III secretion to inhibit <i>Salmonella enterica</i> serovar typhimurium infection. [PDF]
Ge J +7 more
europepmc +1 more source
Jieling Yang +3 more
semanticscholar +1 more source
Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras +6 more
wiley +1 more source
Molecular epidemiological association between antimicrobial resistance characteristics and type III secretion system in carbapenem-resistant <i>Pseudomonas aeruginosa</i> from lower respiratory tract infections. [PDF]
Zhou Y +5 more
europepmc +1 more source
Mechanoregulatory Effects of Cell‐Scale Microwells on Epithelial Cell Phenotype
In small polycaprolactone microwells, A549 epithelial cells span well edges, in contrast to cells growing on flat substrates. Focal adhesion sites (yellow) concentrate at topographic boundaries, while cytoskeletal tension (magenta stress fibers) is transmitted to the nucleus (blue), reducing nuclear sphericity.
Ruiwen He +10 more
wiley +1 more source
The Catabolite Repression Control Protein Crc Regulates the Type III Secretion System Through the Adenylate Cyclase CyaB in <i>Pseudomonas aeruginosa</i>. [PDF]
Yin L +7 more
europepmc +1 more source
Type III Secretion: Building and Operating a Remarkable Nanomachine.
Athina G. Portaliou +4 more
semanticscholar +1 more source
Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu +13 more
wiley +1 more source
<i>In situ</i> analysis of type III secretion chaperone proteins indicates a cytosolic handover of virulence effectors. [PDF]
Pintor K +7 more
europepmc +1 more source

