Results 301 to 310 of about 1,118,779 (342)

Recombinant protein secretion via the type III secretion system

Korean Journal of Chemical Engineering, 2011
The type III secretion system (T3SS) is a mechanism by which bacteria export proteins from the cytoplasm, through the membranes, to the extracellular environment. T3SS is made up of more than 20 different proteins, about half of which maintain conserved sequences.
Le Tam Dinh Vo, Soon Ho Hong
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Revisiting the chlamydial type III protein secretion system: clues to the origin of type III protein secretion

Trends in Genetics, 2001
The bacterial type III secretion pathway delivers effector proteins into eukaryotic cells. Analysis of the type III system and flagellar export genes in the obligate parasites of the family Chlamydiales suggests that the type III system arose from the flagellar export system in chlamydiae or related bacteria.
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Port of entry – the type III secretion translocon

Trends in Microbiology, 2002
Many Gram-negative plant and animal pathogenic bacteria use a specialized type III secretion system (TTSS) as a molecular syringe to inject effector proteins directly into the host cell. Protein translocation across the eukaryotic host cell membrane is presumably mediated by a bacterial translocon.
Daniela, Büttner, Ulla, Bonas
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The Type III Secretion System Sorting Platform

2019
A central feature of type III protein secretion machines is their ability to engage their substrates in a hierarchical and organized fashion. The hierarchy in the secretion process is first observed during the assembly of the type III secretion injectisome when the secretion machine exclusively engages proteins required for building the needle complex ...
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Structures of Type III Secretion System Needle Filaments

2019
Among the Gram-negative bacterial secretion systems, type III secretion systems (T3SS) possess a unique extracellular molecular apparatus called the needle. This macromolecular protein assembly is a nanometre-size filament formed by the helical arrangement of hundreds of copies of a single, small protein, which is highly conserved between T3SSs from ...
Habenstein, Birgit, El Mammeri, Nadia, Tolchard, James, Lamon, Gaëlle, Tawani, Arpita, Berbon, Mélanie, Loquet, Antoine   +6 more
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The elusive type III secretion signal

Trends in Microbiology, 2000
Type III secretion systems (TTSS) are virulence factors used by Gram-negative bacteria to translocate bacterial effector proteins directly from the bacterium into the eukaryotic host cell cytoplasm. Unlike proteins secreted by the general secretory pathway, type III secreted effectors do not share consensus signal sequences in their amino termini that ...
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Detecting Immune Responses to Type III Secretion Systems

2016
Measuring immune responses against type III secretion and related molecules has been made easier with the advent of reporter cell lines. For example, the THP-1-XBlue and HEK-Blue cells from InvivoGen provide easy detection of gene activation under NF-kB and AP-1 control.
Peter L, Knopick, David S, Bradley
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[Progress in type III secretion system].

Wei sheng wu xue bao = Acta microbiologica Sinica, 2009
Many Gram-negative bacteria use the type III secretion system (TTSS) to inject toxin proteins into host cells, then cause the plague disease, typhoid fever, diarrhea disease etc. Chaperone proteins is one of four components of MTSS and play an important role in helping the secretion of toxin proteins.
Li, Wang, Yu-Ming, Wang, Jun-Jie, Yue, Long, Liang, Pei-Tang, Huang   +4 more
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The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

Nature, 2011
Yue Zhao, Jieling Yang, Jianjin Shi, Yi-Nan Gong, Qiuhe Lu, Hao Xu, Liping Liu, F. Shao   +7 more
semanticscholar   +1 more source

Type III Secretion

Abstract Gram-negative pathogens have evolved a remarkable arsenal of molecular machines to manipulate their surroundings and facilitate survival and propagation, including several protein secretion systems. The type III secretion system (T3SS) is a syringe-like nanomachine that allows bacteria to transfer proteins into eukaryotic target cells in a one-
Chen, H., Ermoli, F., Diepold, A.
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