Results 51 to 60 of about 373,461 (150)

Bacterial rotary export ATPases are allosterically regulated by the nucleotide second messenger cyclic-di-GMP [PDF]

, 2015
The widespread second messenger molecule cyclic di-GMP (cdG) regulates the transition from motile and virulent lifestyles to sessile, biofilm-forming ones in a wide range of bacteria. Many pathogenic and commensal bacterial-host interactions are known to
Abel, Aldridge, Amikam, Aragón, Barahona, Baraquet, Bell, Benach, Bingle, Boehm, Boyd, Brencic, Christen, Clare E.M. Stevenson, Compant, Cuppels, David M. Lawson, De, Duerig, Eleftheria Trampari, Emsley, Engl, Fazli, Gal, Galibert, Gledhill, Haas, Hengge, Hickman, Ho, Hughes, Iino, Imada, Jacob G. Malone, Jonas, Kelley, Krasteva, Krissinel, Kuchma, Kuchma, Kulasakara, Lee, Lindeberg, Little, Lovering, Lucchini, Lugtenberg, Macnab, Macnab, Martínez-Granero, Matilla, McNicholas, Miller, Minamino, Minamino, Minamino, Minamino, Minamino, Minamino, Minamino, Minamino, Moscoso, Moscoso, Naseby, Navazo, Nesper, Newell, Newell, Pfeilmeier, Pultz, Pérez-Mendoza, Qi, Rainey, Richard H. Little, Roelofs, Ryan, Schirmer, Solano, Srivastava, Starkey, Steiner, Story, Sudarsan, Tchigvintsev, Thomas Wilhelm, Tschowri, Wassmann, Wilhelm, Woodcock, Xin   +89 more
core   +1 more source

Random mutagenesis identifies a C-terminal region of YopD important for Yersinia type III secretion function. [PDF]

PLoS ONE, 2015
A common virulence mechanism among bacterial pathogens is the use of specialized secretion systems that deliver virulence proteins through a translocation channel inserted in the host cell membrane. During Yersinia infection, the host recognizes the type
Rebecca Solomon, Weibing Zhang, Grace McCrann, James B Bliska, Gloria I Viboud   +4 more
doaj   +1 more source

Yersinia type III secretion : send in the effectors [PDF]

, 2002
Pathogenic Yersinia spp (Yersinia pestis, Yersinia pseudotuberculosis, and Yersinia enterocolitica) have evolved an exquisite method for delivering powerful effectors into cells of the host immune system where they inhibit signaling cascades and block ...
Cornelis, G. R.
core   +1 more source

Exploitation of eukaryotic ubiquitin signaling pathways by effectors translocated by bacterial type III and type IV secretion systems. [PDF]

PLoS Pathogens, 2007
The specific and covalent addition of ubiquitin to proteins, known as ubiquitination, is a eukaryotic-specific modification central to many cellular processes, such as cell cycle progression, transcriptional regulation, and hormone signaling ...
Aurélie Angot, Annette Vergunst, Stéphane Genin, Nemo Peeters   +3 more
doaj   +1 more source

Functional plasticity of antibacterial EndoU toxins. [PDF]

, 2018
Bacteria use several different secretion systems to deliver toxic EndoU ribonucleases into neighboring cells. Here, we present the first structure of a prokaryotic EndoU toxin in complex with its cognate immunity protein.
Eschenfeldt, William H, Goulding, Celia W, Hayes, Christopher S, Joachimiak, Andrzej, Jones, Allison M, Koskiniemi, Sanna, Low, David A, Michalska, Karolina, Nguyen, Josephine Y, Quan Nhan, Dinh, Stols, Lucy M, Willett, Julia LE   +11 more
core   +1 more source

P . aeruginosa type III and type VI secretion systems modulate early response gene expression in type II pneumocytes in vitro

BMC Genomics, 2022
Background Lung airway epithelial cells are part of innate immunity and the frontline of defense against bacterial infections. During infection, airway epithelial cells secrete proinflammatory mediators that participate in the recruitment of immune cells.
Emel Sen-Kilic, Annalisa B. Huckaby, F. Heath Damron, Mariette Barbier   +3 more
doaj   +1 more source

Molecular Mechanisms Used by Salmonella to Evade the Immune System [PDF]

, 2017
Human and animal pathogens are able to circumvent, at least temporarily, the sophisticated immune defenses of their hosts. Several serovars of the Gram-negative bacterium Salmonella enterica have been used as models for the study of pathogen-host ...
Bernal Bayard, Joaquín, Ramos Morales, Francisco   +1 more
core   +1 more source

Structural Insights of Shigella Translocator IpaB and Its Chaperone IpgC in Solution

Frontiers in Cellular and Infection Microbiology, 2021
Bacterial Type III Secretion Systems (T3SSs) are specialized multicomponent nanomachines that mediate the transport of proteins either to extracellular locations or deliver Type III Secretion effectors directly into eukaryotic host cell cytoplasm ...
Mariana L. Ferrari, Mariana L. Ferrari, Spyridoula N. Charova, Philippe J. Sansonetti, Philippe J. Sansonetti, Philippe J. Sansonetti, Efstratios Mylonas, Anastasia D. Gazi, Anastasia D. Gazi, Anastasia D. Gazi   +9 more
doaj   +1 more source

Relevance of bacterial secretion systems Type III and Type VI in the Bradyrhizobium-Lupinus simbiosis [PDF]

, 2015
One of the most studied models in plant-microbe interaction is the symbiosis Rhizobium-legume. This symbiosis is highly specific and depends on several molecular signals produced by both partners.
Duran Wendt, David Ricardo, Imperial Ródenas, Juan, Pacheco, Alba, Palacios Alberti, Jose Manuel, Rey Navarro, Luis, Ruiz Argüeso, Tomas-Andres   +5 more
core  

Structural analysis of Salmonella enterica effector protein SopD [PDF]

, 2004
Salmonella outer protein D (SopD) is a type III secreted virulence effector protein from Salmonella enterica. Full-length SopD and SopD lacking 16 amino acids at the N-terminus (SopDDeltaN) have been expressed as fusions with GST in Escherichia coli ...
Bagby, S, Galyov, E E, Gill, A C, Philippe, D L, Upadhyay, A, van den Elsen, J M H, Williams, C, Wood, M W   +7 more
core   +1 more source