Global transcriptional profiling of Burkholderia pseudomallei under salt stress reveals differential effects on the Bsa type III secretion system. [PDF]
, 2010 BACKGROUND: Burkholderia pseudomallei is the causative agent of melioidosis where the highest reported incidence world wide is in the Northeast of Thailand, where saline soil and water are prevalent.
Stabler, Richard A. +30 more
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Assembly and regulation of the type III secretion system of "Yersinia enterocolitica" [PDF]
, 2010 We investigated the assembly of the Yersinia enterocolitica type III secretion injectisome by grafting fluorescent proteins onto several components, YscC (outer-membrane (OM) ring), YscD (forms the inner-membrane (IM) ring together with YscJ), YscN ...
Diepold, Andreas
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Type VI secretion system : secretion by a contractile nanomachine [PDF]
, 2015 The type VI secretion systems (T6SS) are present in about a quarter of all Gram-negative bacteria. Several key components of T6SS are evolutionarily related to components of contractile nanomachines such as phages and R-type pyocins. The T6SS assembly is
Basler, Marek
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Always one step ahead: How pathogenic bacteria use the type III secretion system to manipulate the intestinal mucosal immune system [PDF]
, 2011 The intestinal immune system and the epithelium are the first line of defense in the gut. Constantly exposed to microorganisms from the environment, the gut has complex defense mechanisms to prevent infections, as well as regulatory pathways to tolerate ...
Anna Vossenkämper +5 more
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Structure of the type III secretion effector protein ExoU in complex with its chaperone SpcU. [PDF]
PLoS ONE, 2012 Disease causing bacteria often manipulate host cells in a way that facilitates the infectious process. Many pathogenic gram-negative bacteria accomplish this by using type III secretion systems.
Andrei S Halavaty +8 more
doaj +1 more source
Microreview: type IV secretion systems: versatility and diversity in function [PDF]
, 2010 Type IV secretion systems (T4SSs) are large protein complexes which traverse the cell envelope of many bacteria. They contain a channel through which proteins or protein–DNA complexes can be translocated.
Angel Rivera-Calzada +5 more
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Bacterial secretion systems contribute to rapid tissue decay in button mushroom soft rot disease
mBio, 2023 The soft rot pathogen Janthinobacterium agaricidamnosum causes devastating damage to button mushrooms (Agaricus bisporus), one of the most cultivated and commercially relevant mushrooms.
Philipp Wein +7 more
doaj +1 more source
Bacterial flagella and type III secretion systems [PDF]
FEMS Microbiology Letters, 2001 Certain classes of pathogenic bacteria secrete virulence proteins in a Sec-independent manner, by a mechanism known as type III secretion. The main body of the export apparatus specific for virulence proteins is identified as a needle complex, which has a similar structural organization to flagella. The two structures share several proteins with highly
openaire +2 more sources
Molecular Mechanisms of Bacterial Virulence: Type III Secretion and Pathogenicity Islands
Emerging Infectious Diseases, 1996 Recently, two novel but widespread themes have emerged in the field of bacterial virulence: type III secretion systems and pathogenicity islands. Type III secretion systems, which are found in various gram-negative organisms, are specialized for the ...
Joan Mecsas, Evelyn J. Strauss
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Integrated regulation of the type III secretion system and other virulence determinants in Ralstonia solanacearum [PDF]
, 2006 In many plant and animal bacterial pathogens, the Type III secretion system (TTSS) that directly translocates effector proteins into the eukaryotic host cells is essential for the development of disease.
Christian Boucher +8 more
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