Beyond movement: the dynamic roles of Type IV pili in cyanobacterial life [PDF]
Journal of BacteriologyType IV pili are versatile prokaryotic cell appendages that are extremely widespread in the bacterial and archaeal domains of life. The structure, dynamics, and functions of type IV pili have been most intensively studied in several species of ...
Jonas Hammerl +4 more
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Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms [PDF]
Nature CommunicationsType IV pili (T4P) are prevalent, polymeric surface structures in pathogenic bacteria, making them ideal targets for effective vaccines. However, bacteria have evolved efficient strategies to evade type IV pili-directed antibody responses.
David Fernandez-Martinez +11 more
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Type IV Pili in Thermophilic Bacteria: Mechanisms and Ecological Implications [PDF]
BiomoleculesType IV pili (T4P) machinery is critical for bacterial surface motility, protein secretion, and DNA uptake. This review highlights the ecological significance of T4P-dependent motility in Thermus thermophilus, a thermophilic bacterium isolated from hot ...
Naoki A. Uemura, Daisuke Nakane
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Visualization of Type IV Pili: Linking Structural Architecture, Dynamic Function, and Translational Opportunities [PDF]
BiologyType IV pili are widespread and multifunctional filamentous nanomachines that contribute to bacterial motility, adhesion, surface sensing, DNA uptake, biofilm formation, and, in some organisms, extracellular electron transfer.
Jingchao Zhang, Yutong Liu
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Structural basis of Acinetobacter type IV pili targeting by an RNA virus [PDF]
Nature CommunicationsAcinetobacters pose a significant threat to human health, especially those with weakened immune systems. Type IV pili of acinetobacters play crucial roles in virulence and antibiotic resistance.
Ran Meng +12 more
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Type IV Pili of Streptococcus sanguinis Contribute to Pathogenesis in Experimental Infective Endocarditis [PDF]
Microbiology Spectrum, 2021 Streptococcus sanguinis is a common cause of infective endocarditis (IE). Efforts by research groups are aimed at identifying and characterizing virulence factors that contribute to the ability of this organism to cause IE.
Anthony M. Martini +3 more
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Type IV Pili-Independent Photocurrent Production by the Cyanobacterium Synechocystis sp. PCC 6803 [PDF]
Frontiers in Microbiology, 2020 Biophotovoltaic devices utilize photosynthetic organisms such as the model cyanobacterium Synechocystis sp. PCC 6803 (Synechocystis) to generate current for power or hydrogen production from light.
Miyuki A. Thirumurthy +13 more
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Subcellular localization of type IV pili regulates bacterial multicellular development [PDF]
Nature Communications, 2022 Bacteria can form organized multicellular communities through regulation of cell growth, motility, shape and differentiation. Here, Ellison et al. show that bacterial multicellular development can also be driven by specific patterns of localization of ...
Courtney K. Ellison +6 more
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Analysis of pilus biogenesis genes in bacteria expressing type iv pili [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2018 The structural and sequences similarities of type-IV pili proteins were analysed in Pseudomonas aeruginosa, Vibrio cholerae, Neisseria meningitidis and Neisseria gonorrhoeae.
Saeed AHMED +6 more
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Discovery of a New
mBio, 2020 Neisseria gonorrhoeae relies on type IV pili (T4p) to promote colonization of their human host and to cause the sexually transmitted infection gonorrhea.
Linda I. Hu +6 more
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