Results 1 to 10 of about 40,468 (153)

Beyond movement: the dynamic roles of Type IV pili in cyanobacterial life [PDF]

Journal of Bacteriology
Type IV pili are versatile prokaryotic cell appendages that are extremely widespread in the bacterial and archaeal domains of life. The structure, dynamics, and functions of type IV pili have been most intensively studied in several species of ...
Jonas Hammerl, Nils Schuergers, Gen Enomoto, Conrad W. Mullineaux, Annegret Wilde   +4 more
doaj   +2 more sources

Structural basis of Acinetobacter type IV pili targeting by an RNA virus [PDF]

Nature Communications
Acinetobacters pose a significant threat to human health, especially those with weakened immune systems. Type IV pili of acinetobacters play crucial roles in virulence and antibiotic resistance.
Ran Meng, Zhongliang Xing, Jeng-Yih Chang, Zihao Yu, Jirapat Thongchol, Wen Xiao, Yuhang Wang, Karthik Chamakura, Zhiqi Zeng, Fengbin Wang, Ry Young, Lanying Zeng, Junjie Zhang   +12 more
doaj   +2 more sources

Type IV Pili of Streptococcus sanguinis Contribute to Pathogenesis in Experimental Infective Endocarditis [PDF]

Microbiology Spectrum, 2021
Streptococcus sanguinis is a common cause of infective endocarditis (IE). Efforts by research groups are aimed at identifying and characterizing virulence factors that contribute to the ability of this organism to cause IE.
Anthony M. Martini, Bridget S. Moricz, Laurel J. Woods, Bradley D. Jones   +3 more
doaj   +2 more sources

Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms [PDF]

Nature Communications
Type IV pili (T4P) are prevalent, polymeric surface structures in pathogenic bacteria, making them ideal targets for effective vaccines. However, bacteria have evolved efficient strategies to evade type IV pili-directed antibody responses.
David Fernandez-Martinez, Youxin Kong, Sylvie Goussard, Agustin Zavala, Pauline Gastineau, Martial Rey, Gabriel Ayme, Julia Chamot-Rooke, Pierre Lafaye, Matthijn Vos, Ariel Mechaly, Guillaume Duménil   +11 more
doaj   +2 more sources

Type IV Pili Can Mediate Bacterial Motility within Epithelial Cells [PDF]

mBio, 2019
Pseudomonas aeruginosa is among bacterial pathogens capable of twitching motility, a form of surface-associated movement dependent on type IV pili (T4P). Previously, we showed that T4P and twitching were required for P.
Vincent Nieto, Abby R. Kroken, Melinda R. Grosser, Benjamin E. Smith, Matteo M. E. Metruccio, Patrick Hagan, Mary E. Hallsten, David J. Evans, Suzanne M. J. Fleiszig   +8 more
doaj   +4 more sources

Type IV Pili-Independent Photocurrent Production by the Cyanobacterium Synechocystis sp. PCC 6803 [PDF]

Frontiers in Microbiology, 2020
Biophotovoltaic devices utilize photosynthetic organisms such as the model cyanobacterium Synechocystis sp. PCC 6803 (Synechocystis) to generate current for power or hydrogen production from light.
Miyuki A. Thirumurthy, Andrew Hitchcock, Angelo Cereda, Jiawei Liu, Marko S. Chavez, Bryant L. Doss, Robert Ros, Mohamed Y. El-Naggar, Mohamed Y. El-Naggar, Mohamed Y. El-Naggar, John T. Heap, John T. Heap, Thomas S. Bibby, Anne K. Jones   +13 more
doaj   +2 more sources

Subcellular localization of type IV pili regulates bacterial multicellular development [PDF]

Nature Communications, 2022
Bacteria can form organized multicellular communities through regulation of cell growth, motility, shape and differentiation. Here, Ellison et al. show that bacterial multicellular development can also be driven by specific patterns of localization of ...
Courtney K. Ellison, Chenyi Fei, Triana N. Dalia, Ned S. Wingreen, Ankur B. Dalia, Joshua W. Shaevitz, Zemer Gitai   +6 more
doaj   +2 more sources

Type IV Pili in Thermophilic Bacteria: Mechanisms and Ecological Implications [PDF]

Biomolecules
Type IV pili (T4P) machinery is critical for bacterial surface motility, protein secretion, and DNA uptake. This review highlights the ecological significance of T4P-dependent motility in Thermus thermophilus, a thermophilic bacterium isolated from hot ...
Naoki A. Uemura, Daisuke Nakane
doaj   +2 more sources

The structures of two archaeal type IV pili illuminate evolutionary relationships [PDF]

Nature Communications, 2020
Archaeal type IV pili (T4P) mediate adhesion to surfaces and are receptors for hyperthermophilic archaeal viruses. Here, the authors present the cryo-EM structures of two archaeal T4P from Pyrobaculum arsenaticum and Saccharolobus solfataricus and ...
Fengbin Wang, Diana P. Baquero, Zhangli Su, Leticia C. Beltran, David Prangishvili, Mart Krupovic, Edward H. Egelman   +6 more
doaj   +2 more sources

Expression of Cellulosome Components and Type IV Pili within the Extracellular Proteome of Ruminococcus flavefaciens 007 [PDF]

, 2013
Funding: The Rowett Institute receives funding from SG-RESAS (Scottish Government Rural and Environmental Science and Analysis Service). Visit of M.V.
Bayer, Edward A., Cantlay, Louise, Duncan, Sylvia H., Flint, Harry J., Lamed, Raphael, Marinšek-Logar, Romana, Miller, Margret E. Berg., Parkhill, Julian, Reid, Martin D., Turner, Keith, Vodovnik, Maša, White, Bryan A., Yeoman, Carl J.   +12 more
core   +16 more sources