Results 31 to 40 of about 14,443 (207)

Type IV pili: paradoxes in form and function [PDF]

open access: yesCurrent Opinion in Structural Biology, 2008
Type IV pili are filaments on the surfaces of many Gram-negative bacteria that mediate an extraordinary array of functions, including adhesion, motility, microcolony formation and secretion of proteases and colonization factors. Their prominent display on the surfaces of many bacterial pathogens, their vital role in virulence, and their ability to ...
Lisa, Craig, Juliana, Li
openaire   +2 more sources

Neisseria meningitidis differentially controls host cell motility through PilC1 and PilC2 components of type IV pili [PDF]

open access: yes, 2009
Neisseria meningitidis is a strictly human pathogen that has two facets since asymptomatic carriage can unpredictably turn into fulminant forms of infection.
Thomas F Meyer   +19 more
core   +2 more sources

Microreview: type IV secretion systems: versatility and diversity in function [PDF]

open access: yes, 2010
Type IV secretion systems (T4SSs) are large protein complexes which traverse the cell envelope of many bacteria. They contain a channel through which proteins or protein–DNA complexes can be translocated.
Angel Rivera-Calzada   +5 more
core   +1 more source

Shearing and Enrichment of Extracellular Type IV Pili [PDF]

open access: yes, 2017
Pili are widespread among bacteria. Type IVa pili (T4aP) are associated with a variety of bacterial functions, including adhesion, motility, natural transformation, biofilm formation, and force-dependent signaling. In pathogenic bacteria, T4aP play a crucial role during infection and have been the subject of hundreds of studies.
Alba Katiria, Gonzalez Rivera   +1 more
openaire   +2 more sources

Type IV Pili as a Therapeutic Target [PDF]

open access: yesTrends in Microbiology, 2019
In the age of antibiotic resistance, strategies targeting virulence traits of bacteria are the focus of intense study. Two such studies came out independently a week apart showing that bacterial type IV pili are a promising therapeutic target.
openaire   +2 more sources

Role of Type IV Pili in Virulence of Pseudomonas syringae pv. tabaci 6605: Correlation of Motility, Multidrug Resistance, and HR-Inducing Activity on a Nonhost Plant

open access: yesMolecular Plant-Microbe Interactions, 2011
To investigate the role of type IV pili in the virulence of phytopathogenic bacteria, four mutant strains for pilus biogenesis-related genes were generated in Pseudomonas syringae pv. tabaci 6605. PilA encodes the pilin protein as a major subunit of type
Fumiko Taguchi, Yuki Ichinose
doaj   +1 more source

Potential interactions between syntrophic bacteria and methanogens via type IV pili and quorum-sensing systems

open access: yesEnvironment International, 2020
Interspecies electron transfer plays an important role in syntrophic methanogenesis. Direct interspecies electron transfer (DIET) between syntrophic oxidizers and methanogens via conductive pili has been only confirmed in some specific co-cultures.
Qidong Yin   +4 more
doaj   +1 more source

The Flp type IV pilus operon of Mycobacterium tuberculosis is expressed upon interaction with macrophages and alveolar epithelial cells

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
The genome of Mycobacterium tuberculosis (Mtb) harbors the genetic machinery for assembly of the Fimbrial low-molecular-weight protein (Flp) type IV pilus. Presumably, the Flp pilus is essential for pathogenesis.
Christopher J. Alteri   +13 more
doaj   +1 more source

Pulling Together with Type IV Pili

open access: yesMicrobial Physiology, 2004
Type IV pili are an efficient and versatile device for bacterial surface motility. They are widespread among the β-, γ-, and δ-proteobacteria and the cyanobacteria. Within that diversity, there is a core of conserved proteins that includes the pilin (PilA), the motors PilB and PilT, and various components of pilus biogenesis and assembly, PilC, PilD ...
Eric, Nudleman, Dale, Kaiser
openaire   +2 more sources

Type IV pili mechanochemically regulate virulence factors in Pseudomonas aeruginosa [PDF]

open access: yes, 2015
Bacteria have evolved a wide range of sensing systems to appropriately respond to environmental signals. Here we demonstrate that the opportunistic pathogen Pseudomonas aeruginosa detects contact with surfaces on short timescales using the mechanical ...
Persat, Alexandre   +4 more
core   +1 more source

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