Bridging Bacteria and the Gut: Functional Aspects of Type IV Pili [PDF]
Cell-surface-located proteinaceous appendages, such as flagella and fimbriae or pili, are ubiquitous in bacterial communities. Here, we focus on conserved type IV pili (T4P) produced by bacteria in the intestinal tract, one of the most densely populated human ecosystems.
Ligthart, Kate +3 more
openaire +3 more sources
Structural and Evolutionary Analyses Show Unique Stabilization Strategies in the Type IV Pili of Clostridium difficile [PDF]
SummaryType IV pili are produced by many pathogenic Gram-negative bacteria and are important for processes as diverse as twitching motility, biofilm formation, cellular adhesion, and horizontal gene transfer.
Piepenbrink, Kurt H. +18 more
core +2 more sources
Gram-Positive Type IV Pili and Competence
ABSTRACT Type IV pili (T4P) are remarkable bacterial surface appendages that carry out a range of functions. Various types of T4P have been identified in bacteria and archaea, making them almost universal structures in prokaryotes.
Sandra, Muschiol +3 more
openaire +2 more sources
Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease [PDF]
International audienceBacterial virulence factors are attractive targets for the development of therapeutics. Type IV pili, which are associated with a remarkable array of properties including motility, the interaction between bacteria and attachment to ...
Lafont, Frank +17 more
core +1 more source
Bacterial cells can display different types of motility, due to the presence of external appendages such as flagella and type IV pili. To date, little information on the mechanisms involved in the motility of the Lysobacter species has been available ...
Selena Tomada +5 more
doaj +1 more source
Direct observation of extension and retraction of type IV pili [PDF]
Type IV pili are thin filaments that extend from the poles of a diverse group of bacteria, enabling them to move at speeds of a few tenths of a micrometer per second. They are required for twitching motility, e.g., in Pseudomonas aeruginosa and Neisseria gonorrhoeae , and for social ...
Skerker, Jeffrey M., Berg, Howard C.
openaire +4 more sources
FrzS regulates social motility in Myxococcus xanthus by controlling exopolysaccharide production. [PDF]
Myxococcus xanthus Social (S) motility occurs at high cell densities and is powered by the extension and retraction of Type IV pili which bind ligands normally found in matrix exopolysaccharides (EPS).
James E Berleman +5 more
doaj +1 more source
Biofilm formation by Pseudomonas aeruginosa wild type, flagella and type IV pili mutants [PDF]
Biofilm formation by Gfp-tagged Pseudomonas aeruginosa PAO1 wild type, flagella and type IV pili mutants in flow chambers irrigated with citrate minimal medium was characterized by the use of confocal laser scanning microscopy and comstat image analysis.
Klausen, M. +6 more
core +1 more source
Infections by pathogenic Acinetobacter species represent a significant burden on the health care system, despite their relative rarity, due to the difficulty of treating infections through oral antibiotics.
Nam Vo +3 more
doaj +1 more source
Characterization of the ATPase FlaI of the motor complex of the Pyrococcus furiosus archaellum and its interactions between the ATP-binding protein FlaH [PDF]
The archaellum, the rotating motility structure of archaea, is best studied in the crenarchaeon Sulfolobus acidocaldarius. To better understand how assembly and rotation of this structure is driven, two ATP-binding proteins, FlaI and FlaH of the motor ...
Paushali Chaudhury +2 more
doaj +2 more sources

