Results 51 to 60 of about 9,001,251 (226)
Neisseria meningitidis differentially controls host cell motility through PilC1 and PilC2 components of type IV pili [PDF]
, 2009 Neisseria meningitidis is a strictly human pathogen that has two facets since asymptomatic carriage can unpredictably turn into fulminant forms of infection.
Thomas F Meyer +19 more
core +2 more sources
Discovery of a New
mBio, 2020 Neisseria gonorrhoeae relies on type IV pili (T4p) to promote colonization of their human host and to cause the sexually transmitted infection gonorrhea.
Linda I. Hu +6 more
doaj +1 more source
Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease
Nature Microbiology, 2019 International audienceBacterial virulence factors are attractive targets for the development of therapeutics. Type IV pili, which are associated with a remarkable array of properties including motility, the interaction between bacteria and attachment to ...
Kevin Denis +17 more
semanticscholar +2 more sources
Direct observation of extension and retraction of type IV pili [PDF]
Proceedings of the National Academy of Sciences, 2001 Type IV pili are thin filaments that extend from the poles of a diverse group of bacteria, enabling them to move at speeds of a few tenths of a micrometer per second. They are required for twitching motility, e.g., in Pseudomonas aeruginosa and Neisseria gonorrhoeae
Jeffrey M. Skerker, H. Berg
semanticscholar +5 more sources
Molecular Plant-Microbe Interactions, 2011 To investigate the role of type IV pili in the virulence of phytopathogenic bacteria, four mutant strains for pilus biogenesis-related genes were generated in Pseudomonas syringae pv. tabaci 6605. PilA encodes the pilin protein as a major subunit of type
Fumiko Taguchi, Yuki Ichinose
doaj +1 more source
Pulling Together with Type IV Pili
Microbial Physiology, 2004 Type IV pili are an efficient and versatile device for bacterial surface motility. They are widespread among the β-, γ-, and δ-proteobacteria and the cyanobacteria. Within that diversity, there is a core of conserved proteins that includes the pilin (PilA), the motors PilB and PilT, and various components of pilus biogenesis and assembly, PilC, PilD ...
Eric, Nudleman, Dale, Kaiser
openaire +2 more sources
Type IV Pili as a Therapeutic Target [PDF]
Trends in Microbiology, 2019 In the age of antibiotic resistance, strategies targeting virulence traits of bacteria are the focus of intense study. Two such studies came out independently a week apart showing that bacterial type IV pili are a promising therapeutic target.
openaire +2 more sources
Frontiers in Cellular and Infection Microbiology, 2022 The genome of Mycobacterium tuberculosis (Mtb) harbors the genetic machinery for assembly of the Fimbrial low-molecular-weight protein (Flp) type IV pilus. Presumably, the Flp pilus is essential for pathogenesis.
Christopher J. Alteri +13 more
doaj +1 more source
Shearing and Enrichment of Extracellular Type IV Pili [PDF]
, 2017 Pili are widespread among bacteria. Type IVa pili (T4aP) are associated with a variety of bacterial functions, including adhesion, motility, natural transformation, biofilm formation, and force-dependent signaling. In pathogenic bacteria, T4aP play a crucial role during infection and have been the subject of hundreds of studies.
Alba Katiria, Gonzalez Rivera +1 more
openaire +2 more sources
Ralstonia solanacearum Needs Flp Pili for Virulence on Potato
Molecular Plant-Microbe Interactions, 2012 Type IV pili are virulence factors in various bacteria. Several subclasses of type IV pili have been described according to the characteristics of the structural prepilin subunit.
Charles K. Wairuri +3 more
doaj +1 more source