Results 71 to 80 of about 14,443 (207)

Structural Diversity in the Type IV Pili of Multidrug-resistant Acinetobacter [PDF]

Journal of Biological Chemistry, 2016
Acinetobacter baumannii is a Gram-negative coccobacillus found primarily in hospital settings that has recently emerged as a source of hospital-acquired infections. A. baumannii expresses a variety of virulence factors, including type IV pili, bacterial extracellular appendages often essential for attachment to host cells.
Piepenbrink, Kurt H, Lillehoj, Erik, Harding, Christian M, Labonte, Jason W, Zuo, Xiaotong, Rapp, Chelsea A, Munson, Robert S, Jr, Goldblum, Simeon E, Feldman, Mario F, Gray, Jeffrey J, Sundberg, Eric J   +10 more
openaire   +3 more sources

\u3cem\u3eClostridium perfringens\u3c/em\u3e Adhesion Through Type IV Pili [PDF]

, 2020
Bacteria infect host cells through several mechanisms, one of which is a surface protein called a type IV pilus. Type IV pili are thin, hair-like protein fibers on the bacterial surface capable of being extended and retracted from a bacterial cell; they ...
Meyer, Alexander, Piepenbrink, Kurt, Liess, Josephine   +2 more
core   +1 more source

Recognition of extracellular DNA by type IV pili promotes biofilm formation by \u3ci\u3eClostridioides difficile\u3c/i\u3e [PDF]

, 2022
Clostridioides difficile is a Gram-positive bacillus, which is a frequent cause of gastrointestinal infections triggered by the depletion of the gut microbiome. Because of the frequent recurrence of these infections after antibiotic treatment, mechanisms
Sidner, Ben, Piepenbrink, Kurt H., Yu, Yafan, Ronish, Leslie A.   +3 more
core   +1 more source

Revisiting Burn Wound Infections: A Comprehensive Review on the Dual Potential of Phages and Probiotics Against Acinetobacter baumannii

Journal of Clinical Laboratory Analysis, EarlyView.
Effect Probiotics on immune system modulation and wound Healing. ABSTRACT Introduction Burn wound infections caused by Acinetobacter baumannii remain a critical clinical challenge due to its extensive multidrug resistance, particularly against carbapenems.
Zeinab Fagheei Aghmiyuni, Shahrzad Aliniay Sharafshadehi, Roghayeh Afifirad, Elnaz Bafandeh, Maryam Mokhtaryan, Roya Ghanavati, Atieh Darbandi   +6 more
wiley   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari, Hadi Sedigh Ebrahim‐Saraie, Majid Taati Moghadam, Meysam Hasannejad‐Bibalan   +3 more
wiley   +1 more source

Steered molecular dynamics simulations of a type IV pilus probe initial stages of a force-induced conformational transition. [PDF]

PLoS Computational Biology, 2013
Type IV pili are long, protein filaments built from a repeating subunit that protrudes from the surface of a wide variety of infectious bacteria. They are implicated in a vast array of functions, ranging from bacterial motility to microcolony formation ...
Joseph L Baker, Nicolas Biais, Florence Tama   +2 more
doaj   +1 more source

Pulling Together with Type IV Pili Where Are Type IV Pili Found? [PDF]

, 2004
Type IV pili are an efficient and versatile device for bacterial surface motility. They are widespread among the ß-, Á-, and ‰-proteobacteria and the cyanobacteria.
W Secretins, Dale Kaiser, Eric Nudleman, W Pilt, W Fibrils, W Biofilms, W Pilq   +6 more
core  

Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium. [PDF]

, 2009
International audienceType IV pili mediate the initial interaction of many bacterial pathogens with their host cells. In Neisseria meningitidis, the causative agent of cerebrospinal meningitis, type IV pili-mediated adhesion to brain endothelial cells is
Romero, Ignacio, A., Duménil, Guillaume, Mathieu, Coureuil, Coureuil, Mathieu, Weksler, Babette B., Mikaty, Guillain, Bourdoulous, Sandrine, Couraud, Pierre Olivier, Couraud, Pierre-Olivier, Nassif, Xavier, Miller, Florence, Mège, René-Marc, Weksler, Babette, B., Bernard, Christine, Romero, Ignacio A., Lécuyer, Hervé   +15 more
core   +1 more source

Adhesion pilus retraction powers twitching motility in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius

Nature Communications
Type IV pili are filamentous appendages found in most bacteria and archaea, where they can support functions such as surface adhesion, DNA uptake, aggregation, and motility. In most bacteria, PilT-family ATPases disassemble adhesion pili, causing them to
Arthur Charles-Orszag, Marleen van Wolferen, Samuel J. Lord, Sonja-Verena Albers, R. Dyche Mullins   +4 more
doaj   +1 more source

Genomic, Transcriptomic, and Phenotypic Analyses of Neisseria meningitidis Isolates from Disease Patients and Their Household Contacts

mSystems, 2017
Neisseria meningitidis (meningococcus) can cause meningococcal disease, a rapidly progressing and often fatal disease that can occur in previously healthy children.
Xiaoyun Ren, David A. Eccles, Gabrielle A. Greig, Jane Clapham, Nicole E. Wheeler, Stinus Lindgreen, Paul P. Gardner, Joanna K. MacKichan   +7 more
doaj   +1 more source