Results 21 to 30 of about 9,001,251 (226)

Removal of <i>Pseudomonas</i> type IV pili by a small RNA virus. [PDF]

Science
The retractile type IV pilus (T4P) is important for virulence of the opportunistic human pathogen Pseudomonas aeruginosa. The single-stranded RNA (ssRNA) phage PP7 binds to T4P and is brought to the cell surface through pilus retraction.
Thongchol J, Yu Z, Harb L, Lin Y, Koch M, Theodore M, Narsaria U, Shaevitz J, Gitai Z, Wu Y, Zhang J, Zeng L.   +11 more
europepmc   +2 more sources

PlzR regulates type IV pili assembly in Pseudomonas aeruginosa via PilZ binding. [PDF]

Nat Commun
Type IV pili (T4P) are thin, flexible filaments exposed on the cell surface of gram-negative bacteria and are involved in pathogenesis-related processes, including cell adsorption, biofilm formation, and twitching motility. Bacteriophages often use these
Hendrix H, Itterbeek A, Longin H, Delanghe L, Vriens E, Vallino M, Lammens EM, Haque F, Yusuf A, Noben JP, Boon M, Koch MD, van Noort V, Lavigne R.   +13 more
europepmc   +2 more sources

Two distinct archaeal type IV pili structures formed by proteins with identical sequence. [PDF]

Nat Commun
Type IV pili (T4P) represent one of the most common varieties of surface appendages in archaea. These filaments, assembled from small pilin proteins, can be many microns long and serve diverse functions, including adhesion, biofilm formation, motility ...
Liu J, Eastep GN, Cvirkaite-Krupovic V, Rich-New ST, Kreutzberger MAB, Egelman EH, Krupovic M, Wang F.   +7 more
europepmc   +2 more sources

Bacterial flagella hijack type IV pili proteins to control motility. [PDF]

Proc Natl Acad Sci U S A
Significance Bacterial surface appendages, flagella, and type IV pili (TFP) are both reported to sense surfaces, but the mechanisms are not well understood. These organelles operate in different ways—flagella rotate and TFP extend and retract.
Liu X, Tachiyama S, Zhou X, Mathias RA, Bonny SQ, Khan MF, Xin Y, Roujeinikova A, Liu J, Ottemann KM.   +9 more
europepmc   +2 more sources

Surface-Induced cAMP Signaling Requires Multiple Features of the Pseudomonas aeruginosa Type IV Pili. [PDF]

J Bacteriol, 2022
Surface sensing by P. aeruginosa requires TFP. TFP plays a critical role in the induction of the second messenger cAMP upon surface contact; this second messenger is part of a larger cascade involved in the transition from a planktonic to a biofilm ...
Kuchma SL, O'Toole GA.
europepmc   +2 more sources

Recognition of extracellular DNA by type IV pili promotes biofilm formation by Clostridioides difficile. [PDF]

J Biol Chem, 2022
Clostridioides difficile is a Gram-positive bacillus, which is a frequent cause of gastrointestinal infections triggered by the depletion of the gut microbiome. Because of the frequent recurrence of these infections after antibiotic treatment, mechanisms
Ronish LA, Sidner B, Yu Y, Piepenbrink KH.   +3 more
europepmc   +2 more sources

A Filamentous Bacteriophage Protein Inhibits Type IV Pili To Prevent Superinfection of Pseudomonas aeruginosa. [PDF]

mBio, 2022
Pf bacteriophage (phage) are filamentous viruses that infect Pseudomonas aeruginosa and enhance its virulence potential. Pf virions can lyse and kill P. aeruginosa through superinfection, which occurs when an already infected cell is infected by the same
Schmidt AK, Fitzpatrick AD, Schwartzkopf CM, Faith DR, Jennings LK, Coluccio A, Hunt DJ, Michaels LA, Hargil A, Chen Q, Bollyky PL, Dorward DW, Wachter J, Rosa PA, Maxwell KL, Secor PR.   +15 more
europepmc   +2 more sources

Potential interactions between syntrophic bacteria and methanogens via type IV pili and quorum-sensing systems

Environment International, 2020
Interspecies electron transfer plays an important role in syntrophic methanogenesis. Direct interspecies electron transfer (DIET) between syntrophic oxidizers and methanogens via conductive pili has been only confirmed in some specific co-cultures.
Qidong Yin, Mengqi Gu, Slawomir W. Hermanowicz, Hongying Hu, Guangxue Wu   +4 more
doaj   +2 more sources

Type IV pili: e pluribus unum? [PDF]

Molecular Microbiology, 2008
The widespread role of pili as colonization factors in pathogens has long been recognized in Gram-negative bacteria and more recently in Gram-positive bacteria, making the study of these hair-like filaments a perennial hot topic for research.
Pelicic, V, Vladimir Pelicic, Pelicic, V.   +2 more
core   +5 more sources

Cell Signaling by the Type IV Pili of Pathogenic Neisseria [PDF]

Journal of Biological Chemistry, 1998
Neisseria gonorrhoeae andNeisseria meningitidis are Gram-negative bacterial pathogens that infect human mucosal epithelia. Type IV pilus-mediated adherence of these bacteria is a crucial early event for establishment of infection.
Islam, Md. Shahidul, Islam, M. Shahidul,, Källström, Helena, Jonsson, Ann-Beth, Berggren, Per-Olof, Berggren, PO, Källström, H, Jonsson, AB, Islam, MS, Ann-Beth Jonsson, Helena Källström, Md. Shahidul Islam, Per-Olof Berggren   +12 more
core   +3 more sources