Results 11 to 20 of about 14,443 (207)

Archaeal type IV pili and their involvement in biofilm formation [PDF]

Frontiers in Microbiology, 2015
Type IV pili are ancient proteinaceous structures present on the cell surface of species in nearly all bacterial and archaeal phyla. These filaments are involved in a diverse array of critical cellular processes.
Rianne eEsquivel, Mechthild ePohlschroder   +1 more
doaj   +5 more sources

Role of type IV pili in predation by Bdellovibrio bacteriovorus. [PDF]

PLoS ONE, 2014
Bdellovibrio bacteriovorus, as an obligate predator of Gram-negative bacteria, requires contact with the surface of a prey cell in order to initiate the life cycle.
Ryan M Chanyi, Susan F Koval
doaj   +8 more sources

Type IV Pili and Twitching Motility [PDF]

Annual Review of Microbiology, 2002
▪ Abstract  Twitching motility is a flagella-independent form of bacterial translocation over moist surfaces. It occurs by the extension, tethering, and then retraction of polar type IV pili, which operate in a manner similar to a grappling hook. Twitching motility is equivalent to social gliding motility in Myxococcus xanthus and is important in host
Mattick, JS
openaire   +6 more sources

Type IV pili—a numbers game [PDF]

The EMBO Journal, 2014
Abstract Type IV pili are long polymers located on the surface of a wide variety of bacterial cells, including the pathogen Neisseria meningitidis . They are responsible for a diverse range of functions, including adhesion, motility and natural transformation.
Karuppiah, Vijaykumar, Derrick, Jeremy P.   +1 more
openaire   +6 more sources

Structure and function of minor pilins of type IV pili. [PDF]

Med Microbiol Immunol, 2020
AbstractType IV pili are versatile and highly flexible fibers formed on the surface of many Gram-negative and Gram-positive bacteria. Virulence and infection rate of several pathogenic bacteria, such as Neisseria meningitidis and Pseudomonas aeruginosa, are strongly dependent on the presence of pili as they facilitate the adhesion of the bacteria to ...
Jacobsen T, Bardiaux B, Francetic O, Izadi-Pruneyre N, Nilges M.   +4 more
europepmc   +8 more sources

Type IV pili: e pluribus unum? [PDF]

Molecular Microbiology, 2008
SummaryThe widespread role of pili as colonization factors in pathogens has long been recognized in Gram‐negative bacteria and more recently in Gram‐positive bacteria, making the study of these hair‐like filaments a perennial hot topic for research. No other pili are found in as many or as diverse bacteria as type IV pili.
Pelicic, V, Vladimir Pelicic, Pelicic, V.   +2 more
openaire   +6 more sources

Cell Signaling by the Type IV Pili of Pathogenic Neisseria [PDF]

Journal of Biological Chemistry, 1998
Neisseria gonorrhoeae and Neisseria meningitidis are Gram-negative bacterial pathogens that infect human mucosal epithelia. Type IV pilus-mediated adherence of these bacteria is a crucial early event for establishment of infection. In this work, we show that the type IV pili transduce a signal into the eucaryotic host cell.
H, Källström, M S, Islam, P O, Berggren, A B, Jonsson   +3 more
openaire   +4 more sources

Nanoscale Adhesion Forces of Pseudomonas aeruginosa Type IV Pili [PDF]

ACS Nano, 2014
A variety of bacterial pathogens use nanoscale protein fibers called type IV pili to mediate cell adhesion, a primary step leading to infection. Currently, how these nanofibers respond to mechanical stimuli and how this response is used to control adhesion is poorly understood.
Beaussart, Audrey, Baker, Amy E., Kuchma, Sherry L., El-Kirat-Chatel, Sofiane, O’Toole, George A., Dufrêne, Yves F.   +5 more
openaire   +4 more sources

Cryo-electron microscopy reveals two distinct type IV pili assembled by the same bacterium [PDF]

Nature Communications, 2020
Type IV pili are flexible filaments on the surface of bacteria, consisting of a helical assembly of pilin proteins. Here, Neuhaus et al. show that the bacterium Thermus thermophilus produces two forms of type IV pilus, differing in structure, protein ...
Alexander Neuhaus, Muniyandi Selvaraj, Ralf Salzer, Julian D. Langer, Kerstin Kruse, Lennart Kirchner, Kelly Sanders, Bertram Daum, Beate Averhoff, Vicki A. M. Gold   +9 more
doaj   +5 more sources

Attenuation of Type IV pili activity by natural products [PDF]

Journal of Biomolecular Structure and Dynamics
The virulence factor Type IV pili (T4P) are surface appendages used by the opportunistic pathogen Pseudomonas aeruginosa for twitching motility and adhesion in the environment and during infection. Additionally, the use of these appendages by P. aeruginosa for biofilm formation increases its virulence and drug resistance.
Yalkut, Kerem, Ben Ali Hassine, Soumaya, Basaran, Esra, Kula, Ceyda, Ozcan, Aslıhan, Avci, Fatma Gizem, Keskin, Ozlem, Sariyar Akbulut, Berna, Ozbek, Pemra   +8 more
openaire   +4 more sources