Structure and function of minor pilins of type IV pili. [PDF]
Med Microbiol Immunol, 2020 Type IV pili are versatile and highly flexible fibers formed on the surface of many Gram-negative and Gram-positive bacteria. Virulence and infection rate of several pathogenic bacteria, such as Neisseria meningitidis and Pseudomonas aeruginosa , are ...
Jacobsen T +4 more
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Cryo-electron microscopy reveals two distinct type IV pili assembled by the same bacterium [PDF]
Nature Communications, 2020 Type IV pili are flexible filaments on the surface of bacteria, consisting of a helical assembly of pilin proteins. Here, Neuhaus et al. show that the bacterium Thermus thermophilus produces two forms of type IV pilus, differing in structure, protein ...
Alexander Neuhaus +9 more
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Type IV pili of <i>Enterobacteriaceae</i> species. [PDF]
EcoSal PlusType IV pili (T4Ps) are surface filaments widely distributed among bacteria and archaea. T4Ps are involved in many cellular functions and contribute to virulence in some species of bacteria.
Little JI +5 more
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Archaeal type IV pili and their involvement in biofilm formation [PDF]
Frontiers in Microbiology, 2015 Type IV pili are ancient proteinaceous structures present on the cell surface of species in nearly all bacterial and archaeal phyla. These filaments are involved in a diverse array of critical cellular processes.
Rianne eEsquivel +1 more
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Type IV Pili-Independent Photocurrent Production by the Cyanobacterium Synechocystis sp. PCC 6803 [PDF]
Frontiers in Microbiology, 2020 Biophotovoltaic devices utilize photosynthetic organisms such as the model cyanobacterium Synechocystis sp. PCC 6803 (Synechocystis) to generate current for power or hydrogen production from light.
Miyuki A. Thirumurthy +13 more
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Type IV Pili in Thermophilic Bacteria: Mechanisms and Ecological Implications [PDF]
BiomoleculesType IV pili (T4P) machinery is critical for bacterial surface motility, protein secretion, and DNA uptake. This review highlights the ecological significance of T4P-dependent motility in Thermus thermophilus, a thermophilic bacterium isolated from hot ...
Naoki A. Uemura, Daisuke Nakane
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Visualization of Type IV Pili: Linking Structural Architecture, Dynamic Function, and Translational Opportunities [PDF]
BiologyType IV pili are widespread and multifunctional filamentous nanomachines that contribute to bacterial motility, adhesion, surface sensing, DNA uptake, biofilm formation, and, in some organisms, extracellular electron transfer.
Jingchao Zhang, Yutong Liu
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Saccharibacteria deploy two distinct type IV pili, driving episymbiosis, host competition, and twitching motility. [PDF]
ISME JAll cultivated Patescibacteria, also known as the candidate phyla radiation, are obligate episymbionts residing on other microbes. Despite being ubiquitous in many diverse environments, including mammalian microbiomes, molecular mechanisms of host ...
Grossman AS +8 more
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Pseudomonas aeruginosa type IV pili actively induce mucus contraction to form biofilms in tissue-engineered human airways. [PDF]
PLoS Biol, 2023 The opportunistic pathogen Pseudomonas aeruginosa causes antibiotic–recalcitrant pneumonia by forming biofilms in the respiratory tract. Despite extensive in vitro experimentation, how P. aeruginosa forms biofilms at the airway mucosa is unresolved.
Rossy T +8 more
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Pseudomonas aeruginosa distinguishes surfaces by stiffness using retraction of type IV pili. [PDF]
Proc Natl Acad Sci U S A, 2022 Significance While many bacteria can sense the presence of a surface, the mechanical properties of different surfaces vary tremendously and can be as rigid as bone or as soft as mucus.
Koch MD +4 more
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