Results 101 to 110 of about 40,764 (218)

Water, water, every where—the advent of hydrated pili structure

The FEBS Journal, EarlyView.
Protein structure is defined by its surrounding water. Naturally, this is also true for the gigantic protein filaments that pathogenic bacteria use to attach to and colonize their host cells. Structures of these filaments for which water can be identified with high confidence have stayed elusive for the longest time.
Hiroya Oki, Hideki Shigematsu, Kazuki Kawahara, Christoph Gerle   +3 more
wiley   +1 more source

Controlled trial of lovastatin combined with an open-label treatment of a parent-implemented language intervention in youth with fragile X syndrome. [PDF]

, 2020
BackgroundThe purpose of this study was to conduct a 20-week controlled trial of lovastatin (10 to 40 mg/day) in youth with fragile X syndrome (FXS) ages 10 to 17 years, combined with an open-label treatment of a parent-implemented language intervention (
Abbeduto, Leonard, Banasik, Amy, Bullard, Lauren, Hagerman, Randi, Kim, Kyoungmi, McDuffie, Andrea, Nguyen, Vivian, Potter, Laura A, Potter, Sarah Nelson, Tassone, Flora, Thurman, Angela John   +10 more
core  

Pilus distribution among lineages of group b streptococcus: an evolutionary and clinical perspective [PDF]

, 2014
<b>Background</b><p></p> Group B Streptococcus (GBS) is an opportunistic pathogen in both humans and bovines. Epidemiological and phylogenetic analyses have found strains belonging to certain phylogenetic lineages to be more ...
Davies, H Dele, Lacher, David W, Manning, Shannon D, Singh, Pallavi, Springman, Amber Cody, Waymire, Emily A, Wengert, Samantha L, Zadoks, Ruth N   +7 more
core   +1 more source

Force Generation by Type IV pili of Neisseria Gonorrhoeae [PDF]

Biophysical Journal, 2010
Type IV pili are major bacterial virulence factors supporting adhesion, surface motility, and gene transfer. During infection they mediate attachment to mammalian host cells and elicit downstream signals. The polymeric pilus fiber is a highly dynamic molecular machine that switches between elongation and retraction.
Opitz, Dirk, Clausen, Martin, Maier, Berenike   +2 more
openaire   +1 more source

Alopecic Patches on the Extremities of a Young Man

JEADV Clinical Practice, EarlyView.
Hamad El Hajj, Dima Jeha, Samer Ghosn, Hala Abi Rached Megarbane   +3 more
wiley   +1 more source

Serotypic and Genomic Diversity of Vibrio anguillarum in Rainbow Trout Farms in Turkey: Implications for Vibriosis Control and Vaccine Candidate Selection

Journal of Fish Diseases, EarlyView.
ABSTRACT Outbreaks of vibriosis caused by Vibrio anguillarum are a persistent constraint on rainbow trout (Oncorhynchus mykiss) aquaculture. However, information on the population structure of field strains in Turkey has been lacking. Here, we report the first systematic serotypic, proteomic, and genomic characterization of 23 V.
Soner Altun, Muhammed Duman, Jesús L. Romalde, Nihed Ajmi, Gorkem Tasci, Cuneyt Ozakin, Nazmiye Ulku Tuzemen, Bekir Akça, Sebahattin Ergün, Sevdan Yılmaz, Izzet Burcin Saticioglu   +10 more
wiley   +1 more source

Structural basis for the adsorption of a single-stranded RNA bacteriophage

Nature Communications, 2019
Single-stranded RNA bacteriophages use a single maturation protein (Mat) to attach to a retractile pilus of the bacterial host. Here, the authors report the structures of the MS2 phage bound to the host receptor F-pili and define the orientations of Mat ...
Ran Meng, Mengqiu Jiang, Zhicheng Cui, Jeng-Yih Chang, Kailu Yang, Joanita Jakana, Xinzhe Yu, Zhao Wang, Bo Hu, Junjie Zhang   +9 more
doaj   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Circular RNAs in Lotus japonicus Responses to Nutrient Supply and Mesorhizobium Symbiosis

Plant, Cell &Environment, EarlyView.
ABSTRACT Symbiotic interactions between legumes and rhizobia enable nitrogen fixation under low nutrient conditions. The establishment and function of symbiotic interactions require coordinated changes in gene expression in both the host and the microbe. Circular RNAs (circRNAs) are endogenous gene‐specific molecules that can regulate transcription and
Delecia Utley, Asa Budnick, Simona Radutoiu, Heike Sederoff   +3 more
wiley   +1 more source

The Effect of Two Weight Reduction Maintenance Strategies for Moderately/Mildly Retarded Adults [PDF]

, 1986
Thirteen retarded adult subjects were first exposed to a 12-week behavior therapy weight reduction program followed by a ten-month weekly weigh-in. Then the subjects were randomly assigned to an experimental maintenance booster session group (n=7) or a ...
Fox, Robert, Matson, Johnny, Rotatori, Anthony F., Sexton, David, Wade, Patricia, Zinkgraf, Stephen   +5 more
core   +1 more source