Results 221 to 230 of about 24,060,770 (296)

A phospholipase effector of the type VI secretion system modulates plant reproduction. [PDF]

mBio
Tan Z-M, Yang J-T, Xiao Q-J, Su J-T, Wang Z-H, Jiang Y-T, Liu J-S, Pei T-T, Liang X, An Y, Xue H-W, Qin W-M, Lin W-H, Dong T.   +13 more
europepmc   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Type VI secretion system immunity protein Tldi1 modulates host inflammatory responses and gut microbiota homeostasis in chickens infected with Salmonella enterica serovar Typhimurium. [PDF]

Poult Sci
Dai J, Liu C, Zhang J, Yang Y, Chen S, Guo R, Jia Y, Li J, Ding K, Liao C, Shang K.   +10 more
europepmc   +1 more source

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

The multifunctional type VI secretion system of <i>Vibrio parahaemolyticus</i>: from environmental adaptation to interbacterial competition. [PDF]

Appl Environ Microbiol
Wang Y, Ma T, Ye Y.
europepmc   +1 more source

Wearable Morphology‐Adaptive in‐Ear Device With Active Cleansing Capability for Multimodal Health Monitoring

Advanced Materials, EarlyView.
We present SCIENCE, an in‐ear multimodal physiological monitor featuring two key innovations. Water‐triggered morphological expansion (a 2‐mm cylinder to a 9‐mm spindle) achieves conformal adaptation across complex canal geometries. Simultaneously, active biofouling mitigation disrupts cerumen barriers, reducing sensor‐skin impedance by 20%.
Shuyun Zhuo, Zihuan Wu, Anan Zhang, Shideh Kabiri Ameri   +3 more
wiley   +1 more source

The divergent <i>cts1</i> type VI secretion system locus of <i>Citrobacter rodentium</i> is controlled by multiple promoters that are silenced by H-NS, with CpxR contributing to their activation upon derepression. [PDF]

Microbiology (Reading)
Ortiz-Jiménez S, Carrasco-Navarro DS, Puente JL.   +2 more
europepmc   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

<i>Francisella tularensis</i> virulence relies on a conserved putative catalytic triad within the Type VI secretion system component PdpC. [PDF]

FEMS Microbes
Bröms JE, Golovliov I, Alam A, Zhu S, Mateus A, Henry T, Sjöstedt A.   +6 more
europepmc   +1 more source