Results 21 to 30 of about 33,313 (146)
Type VI secretion systems in plant-associated bacteria. [PDF]
Environ Microbiol, 2018 Summary The type VI secretion system (T6SS) is a bacterial nanomachine used to inject effectors into prokaryotic or eukaryotic cells and is thus involved in both host manipulation and interbacterial competition. The T6SS is widespread among Gram‐negative bacteria, mostly within the Proteobacterium Phylum.
Bernal P, Llamas MA, Filloux A.
europepmc +7 more sources
Recruitment of heterologous substrates by bacterial secretion systems for transkingdom translocation
Frontiers in Cellular and Infection Microbiology, 2023 Bacterial secretion systems mediate the selective exchange of macromolecules between bacteria and their environment, playing a pivotal role in processes such as horizontal gene transfer or virulence.
Dolores L. Guzmán-Herrador +2 more
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A binary effector module secreted by a type VI secretion system [PDF]
EMBO reports, 2021 ABSTRACTGram-negative bacteria use type VI secretion systems (T6SSs) to deliver toxic effector proteins into neighboring cells. Cargo effectors are secreted by binding non-covalently to the T6SS apparatus. Occasionally, effector secretion is assisted by an adaptor protein, although the adaptor itself is not secreted.
Dar, Yasmin +3 more
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Secrete or perish: The role of secretion systems in Xanthomonas biology
Computational and Structural Biotechnology Journal, 2021 Bacteria of the Xanthomonas genus are mainly phytopathogens of a large variety of crops of economic importance worldwide. Xanthomonas spp. rely on an arsenal of protein effectors, toxins and adhesins to adapt to the environment, compete with other ...
Cristina E. Alvarez-Martinez +7 more
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The Missing Pieces: The Role of Secretion Systems in Campylobacter jejuni Virulence
Biomolecules, 2023 Campylobacter jejuni is likely the most common bacterial cause of gastroenteritis worldwide, responsible for millions of cases of inflammatory diarrhea characterized by severe abdominal cramps and blood in the stool. Further, C.
Amber D. Gabbert +7 more
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Type VI secretion system [PDF]
Current Biology, 2015 Bacteria employ a variety of tools to survive in a competitive environment. Salomon and Orth describe one such tool-the Type 6 Secretion Systems used by bacteria to deliver a variety of toxins into competing cells.
Salomon, Dor, Orth, Kim
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The Versatile Type VI Secretion System [PDF]
Microbiology Spectrum, 2016 ABSTRACT Bacterial type VI secretion systems (T6SSs) function as contractile nanomachines to puncture target cells and deliver lethal effectors. In the 10 years since the discovery of the T6SS, much has been learned about the structure and function of this versatile protein secretion apparatus.
Christopher J, Alteri, Harry L T, Mobley
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The Francisella Type VI Secretion System [PDF]
Frontiers in Cellular and Infection Microbiology, 2018 Francisella tularensisis subsp. tularensis is an intracellular bacterial pathogen and the causative agent of the life-threatening zoonotic disease tularemia. The Francisella Pathogenicity Island encodes a large secretion apparatus, known as a Type VI Secretion System (T6SS), which is essential for Francisella to escape from its phagosome and multiply ...
Clemens, Daniel L +2 more
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Marker for type VI secretion system effectors [PDF]
Proceedings of the National Academy of Sciences, 2014 Significance The recently discovered type VI secretion system (T6SS) is used by Gram-negative bacteria to deliver effector proteins into both eukaryotic and prokaryotic neighboring cells to mediate virulence and competition, respectively. Even though several T6SS effector families have been described, many T6SSs are not associated with known ...
Dor, Salomon +7 more
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Type VI secretion system in Pseudomonas aeruginosa: secretion and multimerization of VgrG proteins. [PDF]
The Journal of biological chemistry, 2011 Pseudomonas aeruginosa is a Gram-negative bacterium causing chronic infections in cystic fibrosis patients. Such infections are associated with an active type VI secretion system (T6SS), which consists of about 15 conserved components, including the AAA+ ATPase, ClpV. The T6SS secretes two categories of proteins, VgrG and Hcp.
Hachani, Abderrahman +6 more
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