Results 21 to 30 of about 16,373,312 (285)
Nature Communications, 2018 It is unclear how Rhs toxins lacking a PAAR motif are secreted by Type VI secretion systems. Here, the authors show for one of these proteins that the mechanism requires removal of an N-terminal fragment by auto-proteolysis, followed by interaction with ...
Nan Jiang +10 more
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Types I, II, V, and VI secretion system genes in clinical uropathogenic Escherichia coli associate with antibiotic susceptibility, biofilm formation, and persister cells [PDF]
Microbiology SpectrumUropathogenic Escherichia coli (UPEC) often causes recurrent urinary tract infections, where biofilms and persister cells can promote recalcitrance. This study evaluated whether secretion-system marker genes associate with antimicrobial susceptibility ...
Paulina Soból +7 more
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Mutations in Two Paraburkholderia phymatum Type VI Secretion Systems Cause Reduced Fitness in Interbacterial Competition [PDF]
Frontiers in Microbiology, 2017 Paraburkholderia phymatum is a highly effective microsymbiont of Mimosa spp. and has also been shown to nodulate papilionoid legumes. P. phymatum was found to be highly competitive both in a natural environment as well as under controlled test conditions
Samanta Bolzan de Campos +4 more
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Diversity of the type VI secretion systems in the Neisseria spp. [PDF]
Microb Genom, 2023 Complete Type VI Secretion Systems were identified in the genome sequence data of Neisseria subflava isolates sourced from throat swabs of human volunteers. The previous report was the first to describe two complete Type VI Secretion Systems in these isolates, both ...
Calder A, Snyder LAS.
europepmc +3 more sources
A binary effector module secreted by a type VI secretion system [PDF]
The EMBO Reports, 2021 ABSTRACT Gram-negative bacteria use type VI secretion systems (T6SSs) to deliver toxic effector proteins into neighboring cells. Cargo effectors are secreted by binding non-covalently to the T6SS apparatus. Occasionally, effector secretion is assisted by an adaptor protein, although the adaptor itself is not secreted.
Dar, Yasmin +3 more
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Type VI Secretion Systems and the Gut Microbiota. [PDF]
Microbiol Spectr, 2019 ABSTRACT The human colonic microbiota is a dense ecosystem comprised of numerous microbes, including bacteria, phage, fungi, archaea, and protozoa, that compete for nutrients and space. Studies are beginning to reveal the antagonistic mechanisms that gut bacteria use to compete with other members of this ecosystem. In the healthy
Coyne MJ, Comstock LE.
europepmc +4 more sources
Secrete or perish: The role of secretion systems in Xanthomonas biology
Computational and Structural Biotechnology Journal, 2021 Bacteria of the Xanthomonas genus are mainly phytopathogens of a large variety of crops of economic importance worldwide. Xanthomonas spp. rely on an arsenal of protein effectors, toxins and adhesins to adapt to the environment, compete with other ...
Cristina E. Alvarez-Martinez +7 more
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The Missing Pieces: The Role of Secretion Systems in Campylobacter jejuni Virulence
Biomolecules, 2023 Campylobacter jejuni is likely the most common bacterial cause of gastroenteritis worldwide, responsible for millions of cases of inflammatory diarrhea characterized by severe abdominal cramps and blood in the stool. Further, C.
Amber D. Gabbert +7 more
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Type VI secretion system [PDF]
Current Biology, 2015 Bacteria employ a variety of tools to survive in a competitive environment. Salomon and Orth describe one such tool-the Type 6 Secretion Systems used by bacteria to deliver a variety of toxins into competing cells.
Salomon, Dor, Orth, Kim
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The Versatile Type VI Secretion System [PDF]
Microbiology Spectrum, 2016 ABSTRACT Bacterial type VI secretion systems (T6SSs) function as contractile nanomachines to puncture target cells and deliver lethal effectors. In the 10 years since the discovery of the T6SS, much has been learned about the structure and function of this versatile protein secretion apparatus.
Christopher J, Alteri, Harry L T, Mobley
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