Results 71 to 80 of about 33,313 (146)
Francisella tularensistype VI secretion system comes of age [PDF]
Virulence, 2017 Francisella tularensis, a Gram-negative facultative intracellular bacterium, is a causative agent of zoonotic disease tularemia.
Petra, Spidlova, Jiri, Stulik
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PLoS Pathogens, 2010 Bacteria that live in the environment have evolved pathways specialized to defend against eukaryotic organisms or other bacteria. In this manuscript, we systematically examined the role of the five type VI secretion systems (T6SSs) of Burkholderia ...
Sandra Schwarz +9 more
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A modular effector with a DNase domain and a marker for T6SS substrates
Nature Communications, 2019 Bacteria deliver toxic effectors via type VI secretion systems (T6SSs) to dominate competitors. Here, the authors identify a Vibrio antibacterial effector that contains a new DNase toxin domain and a domain of unknown function that can be used as a ...
Biswanath Jana +3 more
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F1000Research, 2017 The versatile and ubiquitous Pseudomonas aeruginosa is an opportunistic pathogen causing acute and chronic infections in predisposed human subjects. Here we review recent progress in understanding P.
Jens Klockgether, Burkhard Tümmler
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T346Hunter: a novel web-based tool for the prediction of type III, type IV and type VI secretion systems in bacterial genomes. [PDF]
PLoS ONE, 2015 T346Hunter (Type Three, Four and Six secretion system Hunter) is a web-based tool for the identification and localisation of type III, type IV and type VI secretion systems (T3SS, T4SS and T6SS, respectively) clusters in bacterial genomes.
Pedro Manuel Martínez-García +2 more
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Towards a complete structural deciphering of Type VI secretion system [PDF]
Current Opinion in Structural Biology, 2018 The Type VI secretion system (T6SS) is a dynamic nanomachine present in many Gram-negative bacteria. Using a contraction mechanism similar to that of myophages, bacteriocins or anti-feeding prophages, it injects toxic effectors into both eukaryotic and prokaryotic cells.
Nguyen, van Son +5 more
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Type VI secretion system sheaths as nanoparticles for antigen display [PDF]
Proceedings of the National Academy of Sciences, 2016 SignificanceCritical aspects that limit use of nanoparticles as vaccine delivery systems include the technical difficulty of preparing particles under conditions that allow controlled protein loading and folding. Biologic nanoparticles offer advantages over chemically derived particles that require harsh organic solvents for preparation.
Elena, Del Tordello +3 more
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Type VI Secretion System Toxins Horizontally Shared between Marine Bacteria
PLOS Pathogens, 2015 The type VI secretion system (T6SS) is a widespread protein secretion apparatus used by Gram-negative bacteria to deliver toxic effector proteins into adjacent bacterial or host cells. Here, we uncovered a role in interbacterial competition for the two T6SSs encoded by the marine pathogen Vibrio alginolyticus. Using comparative proteomics and genetics,
Dor Salomon +6 more
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The MicrobeThe Type VI Secretion System (T6SS) is used as weapon by a variety of Gram-negative bacteria in polymicrobial niche competition. Its characterization and study gained more interest in recent years.
Friederike Pisarz +4 more
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Nature Communications, 2018 Type VI secretion systems (T6SSs) translocate effector proteins into eukaryotic and bacterial recipient cells and are present in many Gram-negative bacteria.
Young-Jun Park +5 more
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