Results 11 to 20 of about 7,163,146 (192)

Cloning of Hamster Type XVII Collagen cDNA, and Pathogenesis of Anti-Type XVII Collagen Antibody and Complement in Hamster Bullous Pemphigoid [PDF]

Journal of Investigative Dermatology, 2002
Bullous pemphigoid is an inflammatory subepidermal blistering skin disease associated with an IgG autoimmune response to the type XVII collagen. The immunopathologic features of bullous pemphigoid can be reproduced in mice by the passive transfer of anti-type XVII collagen antibodies.
Yamamoto, Katsushi, Inoue, Naokazu, Masuda, Riako, Fujimori, Akira, Saito, Toshiyuki, Imajoh-Ohmi, Shinobu, Shinkai, Hiroshi, Sakiyama, Hisako   +7 more
core   +5 more sources

Type XVII collagen

, 2023
Type XVII collagen, also known as 180kD bullous pemphigoid antigen (BP180), is a type II transmembrane collagen. It is expressed in epithelial hemidesmosomes of skin, colonic mucosa, cornea, brain, kidney, and placenta and has a number of binding ...
M. Crespo-Bravo, R.S. Pedersen, S. Sun, M.A. Karsdal   +3 more
openaire   +2 more sources

Pterostilbene and Its Glucoside Induce Type XVII Collagen Expression [PDF]

Natural Product Communications, 2017
The glycosylation of pterostilbene by cultured plant cells of Phytolacca americana gave pterostilbene 4′- O -β-D-glucoside. Both pterostilbene and its 4- O -β-D-glucoside induced type XVII collagen expression in the EpiDermFT EFT-400 human skin cell ...
Hiroki Hamada, Kei Shimoda, Yoshiyuki Horio, Tsubasa Ono, Ryusuke Hosoda, Noriyuki Nakayama, Koichi Urano   +6 more
doaj   +3 more sources

Two major 5′-untranslated regions for type XVII collagen mRNA

Journal of Dermatological Science, 2006
Type XVII collagen is an important structural component of keratinocyte hemidesmosomes and its functional loss in genetic or autoimmune disease results in blistering of the skin. In neoplastic tissue aberrant expression is seen dependent on the stage of the tumor.
van Zalen, Sebastiaan, Nijenhuis, Albertine, Jonkman, Marcel F., Pas, Hendri H.   +3 more
openaire   +3 more sources

Recombinant Type XVII Collagen Inhibits EGFR/MAPK/AP-1 and Activates TGF-β/Smad Signaling to Enhance Collagen Secretion and Reduce Photoaging

Cosmetics
Studies have consistently shown that long-wave ultraviolet A (UVA) radiation triggers skin photoaging, which is evident as reduced elasticity, a loss of firmness, and signs of aging.
Ying He, Shiyu Yin, Ru Xu, Yan Zhao, Yuhang Du, Zhiguang Duan, Daidi Fan   +6 more
doaj   +2 more sources

Physicochemical characterization, cellular bioactivity, and biosafety evaluation of type A recombinant humanized collagen type XVII

Journal of Applied Biomaterials & Functional Materials
Collagen type XVII is a unique transmembrane protein that plays a crucial role in anchoring epithelial cells to the underlying basement membrane. However, the low natural abundance of collagen type XVII in the human body poses significant challenges for ...
Nana Han, Xingxing Gao, Lu Song, Jian Wang, Ling Li, Kaixuan Guo, Huan Hu, Jing Wang, Bo Fan, Yun Zhu, Xia Yang   +10 more
doaj   +3 more sources

Features of epidermolysis bullosa simplex due to mutations in the ectodomain of type XVII collagen

British Journal of Dermatology, 2004
Mutations in COL17A1, coding for type XVII collagen, cause junctional epidermolysis bullosa with an ultrastructural plane of cleavage through the lamina lucida of the epidermal basement membrane.To identify the COL17A1 mutations in a child with reduced type XVII collagen expression and intraepidermal blister formation.Protein expression and level of ...
Pasmooij, A. M. G., van der Steege, G., Pas, H. H., Smitt, J. H. Sillevis, Nijenhuis, A. M., Zuiderveen, J., Jonkman, M. F.   +6 more
core   +4 more sources

Post-transcriptional mechanisms in type XVII collagen synthesis [PDF]

, 2006
In chapter 1 we started with making an inventory of type XVII collagen directed research during the last three decades; on its role in normal healthy tissue and even more on its role in the pathogenesis in a range of diseases. We concluded that, although
Zalen, Sebastiaan van,, Zalen, Sebastiaan van   +1 more
openaire   +15 more sources

Recombinant Humanized Collagen Type XVII Promotes Oral Ulcer Healing via Anti-Inflammation and Accelerate Tissue Healing [PDF]

Journal of Inflammation Research
Yukai Hao,1 Baoling Zhao,1 Dongchao Wu,1 Xuejun Ge,1 Jianmin Han2 1Department of Endodontics, Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001 ...
Hao Y, Zhao B, Wu D, Ge X, Han J
doaj   +1 more source

Type XVII collagen is a key player in tooth enamel formation. [PDF]

Am J Pathol, 2009
Inherited tooth enamel hypoplasia occurs due to mutations in genes that encode major enamel components. Enamel hypoplasia also has been reported in junctional epidermolysis bullosa, caused by mutations in the genes that encode type XVII collagen (COL17), a component of the epithelial-mesenchymal junction. To elucidate the pathological mechanisms of the
Asaka T, Akiyama M, Domon T, Nishie W, Natsuga K, Fujita Y, Abe R, Kitagawa Y, Shimizu H.   +8 more
europepmc   +4 more sources