Results 1 to 10 of about 2,216 (115)

WHO preferred product characteristics for bivalent Salmonella Typhi/Paratyphi A vaccine for comprehensive protection against enteric fever– key considerations and research gaps [version 1; peer review: awaiting peer review] [PDF]

Gates Open Research
In 2021, Salmonella Paratyphi A caused >2 million illnesses, resulting in >14,000 deaths, most of which occurred among children under 5 years of age in socioeconomically deprived populations.
Denise O. Garrett, John A. Crump, Jacob John, Melita A. Gordon, Matthew B. Laurens, Karen H. Keddy, Florian Marks, Xinxue Liu, Senjuti Saha, Andrew J. Pollard, Annelies Wilder-Smith, Ana Belen Ibarz Pavon, Alejandro Craviotto, John Clemens   +13 more
doaj   +2 more sources

Phase II multicentre double-blind randomised controlled trial of a Bivalent VaccInation against Salmonella Typhi and Paratyphi A (BiVISTA) using a controlled human infection model of paratyphoid A infection: study protocol [PDF]

BMJ Open
Introduction Enteric fever, primarily caused by Salmonella enterica Typhi and Salmonella enterica Paratyphi A (SPA), is endemic mainly in South Asia, disproportionately affecting school-age children.
Elizabeth Jones, Xinxue Liu, Andrew J Pollard, Brian Angus, Parvinder Aley, Eleanor Wilson, Hannah Robinson, Amy Flaxman, Prasad S Kulkarni, Nisha Singh, Naina McCann, Young Chan Kim, Margarete Paganotti Vicentine, Oisin Hennigan, Noshi Maria, Claudia I Juarez Molina, Stanislava Koleva, Mohammod K Islam, Nicole Day, Allison MacDonald, Mehreen Adnan, Sophie Vernon, Anirudha Vyankatesh Potey, Abhijeet Dharmadhikari, Sanket Gaidhane, Maheshi Nirmala Ramasamy   +25 more
doaj   +2 more sources

Shifting Enteric Fever Epidemiology in children in Nepal: Is the Burden of Paratyphi on the Rise? [PDF]

Journal of Nepal Medical Association
Nepal has a high burden of enteric fevers. An observational study conducted in a tertiary-level hospital in Nepal over 11 years (2014–2024), reviewing hospital records of all blood culture-positive cases of Salmonella Typhi and Paratyphi in children ...
Shrijana Shrestha, Sanjeev Man Bijukchhe, Saugat Bhandari, Meeru Gurung   +3 more
doaj   +2 more sources

Development and characterization of high-throughput serological assays to measure magnitude and functional immune response against S. Paratyphi A in human samples [PDF]

Frontiers in Immunology
Typhoid and Paratyphoid fever cause a global health burden, especially for the children of Southern Asia. The impact of the disease is further exacerbated by the dramatic increase of antimicrobial resistance.
Martina Carducci, Luisa Massai, Elisa Lari, Bianca Semplici, Silvia Grappi, Noshi Maria, Elizabeth Jones, Valentino Conti, Pietro Piu, Francesco Berlanda Scorza, Miren Iturriza-Gómara, Emanuele Montomoli, Emanuele Montomoli, Andrew J. Pollard, Simona Rondini, Omar Rossi   +15 more
doaj   +2 more sources

The Salmonella Paratyphi A O-Antigen Glycoconjugate Vaccine Is Able to Induce Antibodies with Bactericidal Activity Against a Panel of Clinical Isolates [PDF]

Vaccines
Background: Typhoid and paratyphoid fevers represent a global health burden, especially in Southern Asia, exacerbated by the increase in antimicrobial resistance.
Marika Pinto, Salvatore Durante, Martina Carducci, Luisa Massai, Renzo Alfini, Elli Mylona, Abhilasha Karkey, Stephen Baker, Francesca Micoli, Carlo Giannelli, Omar Rossi, Simona Rondini   +11 more
doaj   +2 more sources

Paratyphi Pneumonia- Does What You Eat Matter? [PDF]

Journal of Clinical and Diagnostic Research, 2022
Most common signs and symptoms of typhoid are localised to gastrointestinal system. Less commonly, extraintestinal infectious complications occur with enteric fever.
VK Vineeth, P Senthur Nambi, Jagadeesh Chandrasekaran, Aarthee Asokan   +3 more
doaj   +1 more source

Incidence of typhoid and paratyphoid fever in Bangladesh, Nepal, and Pakistan: results of the Surveillance for Enteric Fever in Asia Project

The Lancet Global Health, 2022
Summary: Background: Precise enteric fever disease burden data are needed to inform prevention and control measures, including the use of newly available typhoid vaccines.
Denise O Garrett, MD, Ashley T Longley, MPH, Kristen Aiemjoy, PhD, Mohammad T Yousafzai, MPH, Caitlin Hemlock, MS, Alexander T Yu, MD, Krista Vaidya, MSc, Dipesh Tamrakar, MD, Shampa Saha, MPH, Isaac I Bogoch, MD, Kashmira Date, MD, Senjuti Saha, PhD, Mohammad Shahidul Islam, MSPH, K M Ishtiaque Sayeed, MPH, Caryn Bern, MD, Sadia Shakoor, MD, Irum F Dehraj, MSc, Junaid Mehmood, MA, Mohammad S I Sajib, MSc, Maksuda Islam, BA, Rozina S Thobani, MSc, Aneeta Hotwani, MPH, Najeeb Rahman, MSc, Seema Irfan, FCPS, Shiva R Naga, BSc, Ashraf M Memon, MD, Sailesh Pradhan, ProfMD, Khalid Iqbal, MBA, Rajeev Shrestha, ProfPhD, Hafizur Rahman, MDT, Md Mahmudul Hasan, MPH, Saqib H Qazi, FACS, Abdul M Kazi, MPH, Nasir S Saddal, FCPS, Raza Jamal, FCPS, Mohammed J Hunzai, MSc, Tanvir Hossain, MSc, Florian Marks, PhD, Alice S Carter, BA, Jessica C Seidman, PhD, Farah N Qamar, FRCP, Samir K Saha, PhD, Jason R Andrews, MD, Stephen P Luby, ProfMD   +43 more
doaj   +1 more source

The control of poultry salmonellosis using organic agents: an updated overview

Poultry Science, 2022
: Salmonellosis is a severe problem that threatens the poultry sector worldwide right now. Salmonella gallinarium and Salmonella pullorum (Fowl typhoid) are the most pathogenic serovars in avian species leading to systemic infection resulting in severe ...
Mohamed T. El-Saadony, Heba M. Salem, Amira M. El-Tahan, Taia A. Abd El-Mageed, Soliman M. Soliman, Asmaa F. Khafaga, Ayman A. Swelum, Ahmed E. Ahmed, Fahdah A. Alshammari, Mohamed E. Abd El-Hack   +9 more
doaj   +1 more source

A novel Vi-diphtheria toxoid typhoid conjugate vaccine is safe and can induce immunogenicity in healthy Indonesian children 2–11 years: a phase II preliminary report

BMC Pediatrics, 2020
Background Typhoid fever caused by Salmonella enteric serovar Typhi (S. Typhi) is a common cause of morbidity in the world. In 2017, 14.3 million cases of Typhoid and paratyphoid fever occurred globally.
Bernie Endyarni Medise, Soedjatmiko Soedjatmiko, Hartono Gunardi, Rini Sekartini, Hindra Irawan Satari, Sri Rezeki Hadinegoro, Angga Wirahmadi, Mita Puspita, Rini Mulia Sari, Jae Seung Yang, Arijit Sil, Sushant Sahastrabuddhe, Novilia Sjafri Bachtiar   +12 more
doaj   +1 more source

Conservation of the OmpC Porin Among Typhoidal and Non-Typhoidal Salmonella Serovars

Frontiers in Immunology, 2020
Salmonella enterica infections remain a challenging health issue, causing significant morbidity and mortality worldwide. Current vaccines against typhoid fever display moderate efficacy whilst no licensed vaccines are available for paratyphoid fever or ...
Nuriban Valero-Pacheco, Nuriban Valero-Pacheco, Nuriban Valero-Pacheco, Joshua Blight, Gustavo Aldapa-Vega, Gustavo Aldapa-Vega, Phillip Kemlo, Marisol Pérez-Toledo, Marisol Pérez-Toledo, Isabel Wong-Baeza, Ayako Kurioka, Christian Perez-Shibayama, Cristina Gil-Cruz, Luvia E. Sánchez-Torres, Rodolfo Pastelin-Palacios, Armando Isibasi, Arturo Reyes-Sandoval, Paul Klenerman, Constantino López-Macías, Constantino López-Macías, Constantino López-Macías   +20 more
doaj   +1 more source