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Effect of Dietary Tyrosine on Behavior and Ruminal Meta-Taxonomic Profile of Altay Sheep with Different Temperaments [PDF]

Veterinary Sciences
The objective of this study was to evaluate the effect of tyrosine on behavior and ruminal meta-taxonomic profile of Altay sheep. Twelve rams with the lowest behavioral responses to humans and twelve rams with the highest behavioral responses were sorted
Asmita Thapa, Weidong Huang, Shahab Ur Rehman, Muhammad Hammad Zafar, Jinying Zhang, Luoyang Ding, Mengzhi Wang   +6 more
doaj   +2 more sources

Long-Term Hyperglycemia Causes Depressive Behaviors in Mice with Hypoactive Glutamatergic Activity in the Medial Prefrontal Cortex, Which Is Not Reversed by Insulin Treatment

Cells, 2022
The etiology of hyperglycemic-induced depressive behaviors is unclear. We hypothesized that long-term hyperglycemia may induce long-lasting disturbances in glutamatergic signaling and neural damages, causing depressive behaviors. To prove our hypothesis,
Ji Hyeong Baek, Hyeonwi Son, Jae Soon Kang, Dae Young Yoo, Hye Jin Chung, Dong Kun Lee, Hyun Joon Kim   +6 more
doaj   +1 more source

Tyrosine-Dependent Phenotype Switching Occurs Early in Many Primary Melanoma Cultures Limiting Their Translational Value

Frontiers in Oncology, 2021
The use of patient-derived primary cell cultures in cancer preclinical assays, including drug screens and genotoxic studies, has increased in recent years.
Ahmad Najem, Jasper Wouters, Jasper Wouters, Mohammad Krayem, Florian Rambow, Florian Rambow, Malak Sabbah, François Sales, François Sales, Ahmad Awada, Ahmad Awada, Stein Aerts, Stein Aerts, Fabrice Journe, Fabrice Journe, Jean-Christophe Marine, Jean-Christophe Marine, Ghanem E. Ghanem   +17 more
doaj   +1 more source

Phosphomimetic Tyrosine Mutations in Spa47 Inhibit Type Three Secretion ATPase Activity and Shigella Virulence Phenotype

Pathogens, 2022
Shigella is a highly infectious human pathogen responsible for 269 million infections and 200,000 deaths per year. Shigella virulence is absolutely reliant on the injection of effector proteins into the host cell cytoplasm via its type three secretion ...
Koleton D. Hardy, Nicholas E. Dickenson
doaj   +1 more source

Hydrogels and Cubic Liquid Crystals for Non-Invasive Sampling of Low-Molecular-Weight Biomarkers—An Explorative In Vivo Study

Pharmaceutics, 2022
The molecular composition of human skin is altered due to diseases, which can be utilized for non-invasive sampling of biomarkers and disease diagnostics.
Maxim Morin, Skaidre Jankovskaja, Tautgirdas Ruzgas, Joakim Henricson, Chris D. Anderson, Anders Brinte, Johan Engblom, Sebastian Björklund   +7 more
doaj   +1 more source

The Effect of the Acidic Gas Pollutant on Wool Keratin Fiber Structure

Journal of Natural Fibers, 2022
Increase in air pollution caused by acidic gases, such as nitrogen dioxide, call for the need to study potential effects on the structure of textile materials.
Zhe Jiang, Rubing Bai, Jinfang Zhang, Ende Li, Yifan Cui, Ning Zhang, Nan Zhang, Qiang Wang   +7 more
doaj   +1 more source

Roles of the tyrosine isomers meta- tyrosine and ortho- tyrosine in oxidative stress [PDF]

Ageing Research Reviews, 2016
The damage to cellular components by reactive oxygen species, termed oxidative stress, both increases with age and likely contributes to age-related diseases including Alzheimer's disease, atherosclerosis, diabetes, and cataract formation. In the setting of oxidative stress, hydroxyl radicals can oxidize the benzyl ring of the amino acid phenylalanine,
Alfred L. Fisher, Brett R. Ipson
openaire   +3 more sources

Electrochemical Amino Acid Sensing: A Review on Challenges and Achievements

Biosensors, 2021
The rapid growth of research in electrochemistry in the last decade has resulted in a significant advancement in exploiting electrochemical strategies for assessing biological substances.
Kaveh Moulaee, Giovanni Neri
doaj   +1 more source

Archaeal tyrosine recombinases

FEMS Microbiology Reviews, 2021
ABSTRACTThe integration of mobile genetic elements into their host chromosome influences the immediate fate of cellular organisms and gradually shapes their evolution. Site-specific recombinases catalyzing this integration have been extensively characterized both in bacteria and eukarya.
Badel, Catherine, da Cunha, Violette, Oberto, J.   +2 more
openaire   +3 more sources

The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of Src [PDF]

, 2007
The transmembrane receptor 'ROR2' resembles members of the receptor tyrosine kinase family of signalling receptors in sequence but its' signal transduction mechanisms remain enigmatic.
A Schambony, AJ Mikels, AR Afzal, Faraz Khosravi Mardakheh, GC Schwabe, H Hikasa, H van Bokhoven, I Oishi, I Oishi, J Billiard, J Liu, John K. Heath, JP Gorvel, K Alexandropoulos, Lee M. Wheldon, M Miaczynska, M Nishita, M Oldridge, M Sammar, MR Larsen, P Masiakowski, R Ishizawar, Richard Steinhardt, S Stricker, S Takeuchi, SA Beausoleil, Shiva Akbarzadeh, Sonia Talma, Steve M. M. Sweet, TM DeChiara, WC Forrester, Y Liu, Z Songyang   +32 more
core   +8 more sources