Results 1 to 10 of about 1,339,692 (430)
NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22. [PDF]
Journal of Clinical Investigation, 2016 Inflammasomes form as the result of the intracellular presence of danger-associated molecular patterns and mediate the release of active IL-1β, which influences a variety of inflammatory responses.
M. Spalinger +21 more
semanticscholar +8 more sources
Association of phenylalanine and tyrosine metabolism with mortality and response to nutritional support among patients at nutritional risk: a secondary analysis of the randomized clinical trial EFFORT [PDF]
Frontiers in NutritionBackgroundElevated phenylalanine serum level is a surrogate marker of whole-body proteolysis and has been associated with increased mortality in critically ill patients.
Lena C. Buchmueller +15 more
doaj +2 more sources
Archaeal tyrosine recombinases [PDF]
FEMS Microbiology Reviews, 2021 ABSTRACTThe integration of mobile genetic elements into their host chromosome influences the immediate fate of cellular organisms and gradually shapes their evolution. Site-specific recombinases catalyzing this integration have been extensively characterized both in bacteria and eukarya.
Catherine Badel +2 more
openaire +5 more sources
Cells, 2022 The etiology of hyperglycemic-induced depressive behaviors is unclear. We hypothesized that long-term hyperglycemia may induce long-lasting disturbances in glutamatergic signaling and neural damages, causing depressive behaviors. To prove our hypothesis,
Ji Hyeong Baek +6 more
doaj +1 more source
Frontiers in Oncology, 2021 The use of patient-derived primary cell cultures in cancer preclinical assays, including drug screens and genotoxic studies, has increased in recent years.
Ahmad Najem +17 more
doaj +1 more source
JIMD Reports, 2022 Homogentisic acid (HGA) lowering, disease modifying off‐label nitisinone therapy has been used in the United Kingdom National Alkaptonuria Centre (NAC) since 2012.
Mohammad S. Z. Ahmad +6 more
doaj +1 more source
Roles of the tyrosine isomers meta- tyrosine and ortho- tyrosine in oxidative stress [PDF]
Ageing Research Reviews, 2016 The damage to cellular components by reactive oxygen species, termed oxidative stress, both increases with age and likely contributes to age-related diseases including Alzheimer's disease, atherosclerosis, diabetes, and cataract formation. In the setting of oxidative stress, hydroxyl radicals can oxidize the benzyl ring of the amino acid phenylalanine,
Alfred L. Fisher, Brett R. Ipson
openaire +3 more sources
CHIMIA, 2020 Tyramine is a health-adverse biogenic amine, which can accumulate in fermented foods like cheese by decarboxylation of the free amino acid tyrosine by either starter cultures or resident microbes such as lactic acid bacteria including Enterococcus spp ...
Janine Anderegg +2 more
doaj +1 more source
Síndrome de Fanconi e hepatocarcinoma por tirosinemia tipo 1: relato de caso e revisão de literatura
Residência Pediátrica, 2023 INTRODUCTION: Type 1 tyrosinemia is an innate error of tyrosine catabolism, causing an accumulation of its metabolites in the organism, which end up triggering organic changes, especially in the liver, kidneys and central nervous system.
Maria Eduarda Turczyn De Lucca +6 more
doaj +1 more source
Roaming leads to amino acid photodamage: A deep learning study of tyrosine [PDF]
, 2021 Although the amino acid tyrosine is among the main building blocks of life, its photochemistry is not fully understood. Traditional theoretical simulations are neither accurate enough, nor computationally efficient to provide the missing puzzle pieces to the experimentally observed signatures obtained via time-resolved pump-probe spectroscopy or mass ...
arxiv +1 more source