Results 11 to 20 of about 1,021,136 (197)

Transcriptomic insights into the effects of tyrosine on sub-Columbian plumage in H line chickens [PDF]

Frontiers in Veterinary Science
Tyrosine is known to influence melanin generation; however, its involvement in melanin production in chicken feathers is unknown. We evaluated the feather color of H-line chickens fed diets containing different concentrations of tyrosine (0, 0.4, 0.6, 0 ...
Xinlei Wang, Xinlei Wang, Liheng Zhang, Liyu Yang, Pengkun Yang, Pengkun Yang, Yingying Qiao, Zhanbing Han, Jiaying Fan, Jiaying Fan, Qiang Li, Dingding Zhang, Zhuanjian Li, Zhuanjian Li, Xiangtao Kang, Xiangtao Kang, Juan Du, Ruiting Li   +17 more
doaj   +2 more sources

Long-Term Hyperglycemia Causes Depressive Behaviors in Mice with Hypoactive Glutamatergic Activity in the Medial Prefrontal Cortex, Which Is Not Reversed by Insulin Treatment

Cells, 2022
The etiology of hyperglycemic-induced depressive behaviors is unclear. We hypothesized that long-term hyperglycemia may induce long-lasting disturbances in glutamatergic signaling and neural damages, causing depressive behaviors. To prove our hypothesis,
Ji Hyeong Baek, Hyeonwi Son, Jae Soon Kang, Dae Young Yoo, Hye Jin Chung, Dong Kun Lee, Hyun Joon Kim   +6 more
doaj   +1 more source

Synthesis of O-tyrosine Phosphorylated Adducts of Methylphosphonic and Phosphoric Acid Derivatives as Reference Compounds for the Analysis of Biomedical Samples

Вестник войск РХБ защиты, 2023
Organophosphorus chemical agents are included in the 1st List of the Annex on Chemicals of the Convention on the Prohibition of the Development, Production, Stockpiling and Use of Chemical Weapons and on Their Destruction (Chemical Weapons Convention ...
V. I. Krylov, I. I. Krylov, V. A. Yashkir, I. V. Rybalchenko   +3 more
doaj   +1 more source

Mendelian Randomization Analysis Identifies Blood Tyrosine Levels as a Biomarker of Non-Alcoholic Fatty Liver Disease

Metabolites, 2022
Non-alcoholic fatty liver disease (NAFLD) is a complex disease associated with premature mortality. Its diagnosis is challenging, and the identification of biomarkers causally influenced by NAFLD may be clinically useful.
Émilie Gobeil, Ina Maltais-Payette, Nele Taba, Francis Brière, Nooshin Ghodsian, Erik Abner, Jérôme Bourgault, Eloi Gagnon, Hasanga D. Manikpurage, Christian Couture, Patricia L. Mitchell, Patrick Mathieu, François Julien, Jacques Corbeil, Marie-Claude Vohl, Sébastien Thériault, Tõnu Esko, André Tchernof, Benoit J. Arsenault   +18 more
doaj   +1 more source

In Vitro and In Silico Anti-Arboviral Activities of Dihalogenated Phenolic Derivates of L-Tyrosine

Molecules, 2021
Despite the serious public health problem represented by the diseases caused by dengue (DENV), Zika (ZIKV) and chikungunya (CHIKV) viruses, there are still no specific licensed antivirals available for their treatment.
Vanessa Loaiza-Cano, Laura Milena Monsalve-Escudero, Manuel Pastrana Restrepo, Diana Carolina Quintero-Gil, Sergio Andres Pulido Muñoz, Elkin Galeano, Wildeman Zapata, Marlen Martinez-Gutierrez   +7 more
doaj   +1 more source

Vitamin K2 (Menaquinone-7) Reverses Age-Related Structural and Cognitive Deterioration in Naturally Aging Rats

Antioxidants, 2022
Aging is a naturally occurring process inevitably affecting each living human. The brain is adversely affected by aging with increased risks of developing various neurological disorders.
Hany A. Elkattawy, Fatma M. Ghoneim, Mohamed Ahmed Eladl, Eman Said, Hasnaa Ali Ebrahim, Mohamed El-Shafey, Saad Mohamed Asseri, Mohamed El-Sherbiny, Reem Hamoud Alsalamah, Nehal M. Elsherbiny, Shimaa Hadhod   +10 more
doaj   +1 more source

Recent Development of Radiofluorination of Boron Agents for Boron Neutron Capture Therapy of Tumor: Creation of ¹⁸F-Labeled C-F and B-F Linkages

Pharmaceuticals, 2023
Boron neutron capture therapy (BNCT) is a binary therapeutic technique employing a boron agent to be delivered to the tumor site followed by the irradiation of neutrons.
Jin-Pei Deng, Chung-Shan Yu
doaj   +1 more source

On the Applicability of Chitosan Oligomers-Amino Acid Conjugate Complexes as Eco-Friendly Fungicides against Grapevine Trunk Pathogens

Agronomy, 2021
In a context in which the incidence and severity of grapevine fungal diseases is increasing as a result of both climate change and modern management culture practices, reducing the excessive use of phytosanitary products in viticulture represents a major
Laura Buzón-Durán, Natalia Langa-Lomba, Vicente González-García, José Casanova-Gascón, Jesús Martín-Gil, Eduardo Pérez-Lebeña, Pablo Martín-Ramos   +6 more
doaj   +1 more source

Exploring the Interaction of Indole-3-Acetonitrile with Neuroblastoma Cells: Understanding the Connection with the Serotonin and Dopamine Pathways

Biomedicines, 2023
Indole-3-acetonitrile, a compound produced by bacteria and plants as a defense and survival signal in response to attacks, has been recently discovered as a metabolite produced by human cancer cells.
Catarina Moura, Ana Salomé Correia, Nuno Vale   +2 more
doaj   +1 more source

Screening and Structure–Activity Relationship for Selective and Potent Anti-Melanogenesis Agents Derived from Species of Mulberry (Genus Morus)

Molecules, 2022
Tyrosinase is a multifunctional, copper-containing and rate-limiting oxidase that catalyses crucial steps in the melanogenesis pathway and is responsible for skin-pigmentation abnormalities in mammals.
Anna Gryn-Rynko, Beata Sperkowska, Michał S. Majewski   +2 more
doaj   +1 more source