The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of Src [PDF]
, 2007 The transmembrane receptor 'ROR2' resembles members of the receptor tyrosine kinase family of signalling receptors in sequence but its' signal transduction mechanisms remain enigmatic.
A Schambony +32 more
core +8 more sources
Tyrosine Amino Acid as a Foulant for the Heterogeneous Anion Exchange Membrane
Membranes, 2023 The features of organic fouling have been revealed for highly basic anion exchange membranes during prolonged electrodialysis in solutions containing the aromatic amino acid tyrosine. With increased operation time when using MA-41 heterogeneous membranes
Anastasiia Kharina, Tatiana Eliseeva
doaj +1 more source
Tyrosine kinase inhibitors for solid tumors in the past 20 years (2001–2020)
Journal of Hematology & Oncology, 2020 Tyrosine kinases are implicated in tumorigenesis and progression, and have emerged as major targets for drug discovery. Tyrosine kinase inhibitors (TKIs) inhibit corresponding kinases from phosphorylating tyrosine residues of their substrates and then ...
Liling Huang, Shiyu Jiang, Yuankai Shi
semanticscholar +1 more source
Endosymbiosis allows Sitophilus oryzae to persist in dry conditions
Frontiers in Microbiology, 2023 Insects frequently associate with intracellular microbial symbionts (endosymbionts) that enhance their ability to cope with challenging environmental conditions. Endosymbioses with cuticle-enhancing microbes have been reported in several beetle families.
Sthandiwe Nomthandazo Kanyile +3 more
doaj +1 more source
Tyrosine decaging leads to substantial membrane trafficking during modulation of an inward rectifier potassium channel [PDF]
, 2001 Tyrosine side chains participate in several distinct signaling pathways, including phosphorylation and membrane trafficking. A nonsense suppression procedure was used to incorporate a caged tyrosine residue in place of the natural tyrosine at position ...
Brandt, Gabriel S. +7 more
core +3 more sources
Frontiers in Nutrition, 2023 BackgroundThere is a need to better understand the relationship between the diet, the gut microbiota and mental health. Metabolites produced when the human gut microbiota metabolize amino acids may enter the bloodstream and have systemic effects.
Margaret Murray +14 more
doaj +1 more source
Novel Strecker degradation products of tyrosine and dihydroxyphenylalanine
Czech Journal of Food Sciences, 2001 Tyrosine was oxidised with either potassium peroxodisulphate or glyoxal. Volatile reaction products were isolated and analysed by GC/FID and GC/MS, derivatised with diazomethane and analysed by the same methods.
J. Adamiec +3 more
doaj +1 more source
CHIMIA, 2020 Tyramine is a health-adverse biogenic amine, which can accumulate in fermented foods like cheese by decarboxylation of the free amino acid tyrosine by either starter cultures or resident microbes such as lactic acid bacteria including Enterococcus spp ...
Janine Anderegg +2 more
doaj +1 more source
Complex formation of EphB1/Nck/Caskin1 leads to tyrosine phosphorylation and structural changes of the Caskin1 SH3 domain. [PDF]
, 2012 Scaffold proteins have an important role in the regulation of signal propagation. These proteins do not possess any enzymatic activity but can contribute to the formation of multiprotein complexes.
Balázs Annamária +6 more
core +2 more sources
EGF regulates tyrosine phosphorylation and membrane-translocation of the scaffold protein Tks5 [PDF]
, 2013 Background: Tks5/FISH is a scaffold protein comprising of five SH3 domains and one PX domain. Tks5 is a substrate of the tyrosine kinase Src and is required for the organization of podosomes/invadopodia implicated in invasion of tumor cells.
Buday, László +5 more
core +1 more source