Results 21 to 30 of about 15,914 (183)
Chinese Medical Journal, 2019 . Background:. Glioma is the most common primary malignant tumor in the central nervous system. Because of the resistance of glioma to chemoradiotherapy and its aggressive growth, the survival rate of patients with glioma has not improved.
Feng Guan +10 more
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Knockdown of DCLK1 Inhibits Proliferation, Migration and Invasion of Glioma Cells
Zhongliu Fangzhi Yanjiu, 2020 Objective To investigate the effects of DCLK1 on the proliferation, migration and invasion of glioma cells and their mechanisms. Methods The mRNA and protein expression of DCLK1 in glioma tissues and glioma cell lines U87 and A172 were detected by RT ...
YU Jie, YANG Feng, DENG Jian, HU Linwang
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Lectin from Dioclea violacea induces autophagy in U87 glioma cells
International Journal of Biological Macromolecules, 2019 The antitumor activity of DVL, a lectin purified from Dioclea violacea seeds, on the U87 human glioma cell line was evaluated and compared with Canavalia ensiformis lectin (ConA). Treatment with DVL (10-100 μg/mL; 24-96 h) induced alterations in cell morphology, decreased cell numbers and clonogenic survival in a time- and concentration-dependent ...
Ana Paula M, Nascimento +10 more
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Di-san junyi daxue xuebao, 2019 Objective To investigate the effect of S100A9 gene silencing on proliferation and self-renewal ability of human U87 glioma stem cells. Methods Human U87 glioma stem cells were infected with shRNA-S100A9 lentivirus for S100A9 gene silencing, and the ...
CHEN Chen, CHEN Song, HUO Gang
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miR-107 inhibits the proliferation, migration and invasion of glioma cells in vitro [PDF]
Jichu yixue yu linchuang, 2020 Objective To investigate the regulation mechanism of miR-107 on proliferation, migration and invasion of glioma cells. Methods RT-qPCR was used to detect the expression of miR-107 and FOXK1 in human normal astrocytes NHA, glioma cell lines U87, A172 and ...
SUN Mao-cang, LI Xin
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Frontiers in Oncology, 2021 Emerging evidence indicates that microRNA (miR)-193a-3p is involved in the tumor progression of various cancers. However, the biological functions and precise molecular mechanisms of miR-193a-3p in gliomas have not been well documented. Accordingly, this
Yong Cui +8 more
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IDH1R132HMutation Increases U87 Glioma Cell Sensitivity to Radiation Therapy in Hypoxia [PDF]
BioMed Research International, 2014 Objective.IDH1codon 132 mutation (mostly Arg132His) is frequently found in gliomas and is associated with longer survival. However, it is still unclear whetherIDH1mutation renders the cell more vulnerable to current treatment, radio- and chemotherapy.Materials and Methods.
Wang, Xiao-Wei +6 more
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Glioma-derived exosomes drive the differentiation of neural stem cells to astrocytes.
PLoS ONE, 2020 Exosomes appear to be effective inter-cellular communicators delivering several types of molecules, such as proteins and RNAs, suggesting that they could influence neural stem cell (NSC) differentiation.
Krishna D Sharma +9 more
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OASIS/CREB3L1 is induced by endoplasmic reticulum stress in human glioma cell lines and contributes to the unfolded protein response, extracellular matrix production and cell migration. [PDF]
PLoS ONE, 2013 OASIS is a transcription factor similar to ATF6 that is activated by endoplasmic reticulum stress. In this study we investigated the expression of OASIS in human glioma cell lines and the effect of OASIS knock-down on the ER stress response and cell ...
Ravi N Vellanki +2 more
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The nitric oxide donor JS-K sensitizes U87 glioma cells to repetitive irradiation [PDF]
Tumor Biology, 2017 As a potent radiosensitizer nitric oxide (NO) may be a putative adjuvant in the treatment of malignant gliomas which are known for their radio- and chemoresistance. The NO donor prodrug JS-K (O2-(2.4-dinitrophenyl) 1-[(4-ethoxycarbonyl) piperazin-1-yl] diazen-1-ium-1,2-diolate) allows cell-type specific intracellular NO release via enzymatic activation
Heckler, Max +7 more
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