Results 71 to 80 of about 15,914 (183)

GLUL Confers Perivascular Cancer‐Associated Fibroblasts With Pro‐Angiogenic Capacity to Promote Glioma Progression

open access: yesAdvanced Science, Volume 13, Issue 8, 9 February 2026.
Schematic illustration of the proposed model. Primary CAFs are isolated from fresh human GBM specimens according to established protocols. GLUL is essential for pro‐angiogenic capacity of CAFs through its impact on the PI3K/AKT pathway. GLUL enhances the pro‐angiogenic capacity of CAFs, driving aberrant tumor vasculature that fuels tumor growth ...
Qing Zhang   +4 more
wiley   +1 more source

The Effect of CXCR4 Silencing on Epithelial‐Mesenchymal Transition Related Genes in Glioma U87 Cells [PDF]

open access: yesThe Anatomical Record, 2013
ABSTRACTThe epithelial–mesenchymal transition (EMT) of tumor cells is deemed to be closely associated with tumor metastasis. CXCR4 has been proved to play an important role in the process of tumor metastasis. This study illustrates the function and expression of CXCR4 silencing and the EMT related genes in the human glioma cell line U87.
Yu, Zhu   +11 more
openaire   +2 more sources

Surface‐Coated Inorganic Nanomaterials for Drug Delivery: Chemical Design, Biomedical Applications, and Mechanistic Insights

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review explores how surface‐coated inorganic nanomaterials are chemically engineered for advanced drug delivery. It highlights design principles, coating strategies, and biomedical applications, emphasizing how surface chemistry governs biocompatibility, targeting, and controlled release.
Hossein Daneshgar   +4 more
wiley   +1 more source

Bortezomib inhibits growth and sensitizes glioma to temozolomide (TMZ) via down-regulating the FOXM1–Survivin axis

open access: yesCancer Communications, 2019
Background High-grade glioma (HGG) is a fatal human cancer. Bortezomib, a proteasome inhibitor, has been approved for the treatment of multiple myeloma but its use in glioma awaits further investigation.
Jun-Hai Tang   +11 more
doaj   +1 more source

Anticancer Molecular Mechanisms of Curcuminoids: An Updated Review of Clinical Trials

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
Curcuminoids remain one of the most studied dietary polyphenols as a cancer prevention and treatment agent. Inflammation and tumor progression are related to the NF‐κB signaling pathway, which is also suppressed by curcuminoids. Curcuminoids prevent the activation of a variety of signaling pathways, including the MAPK, PI3K/Akt, and NF‐kB pathways ...
Ushna Momal   +14 more
wiley   +1 more source

Mechanism of As2O3 induces apoptosis of glioma U87 cells.

open access: yesEuropean review for medical and pharmacological sciences, 2018
To investigate the mechanism of arsenic trioxide (As2O3)-induced apoptosis of glioma cells.U87 cells were treated by different concentrations of As2O3 (8 μmol/L, 6 μmol/L, 4 μmol/L, 2 μmol/L, 1 μmol/L and 0.5 μmol/L) for 24 h, 48 h and 72 h, respectively.
G-B, Wang, J-H, Liu, J, Hu, K, Xue
openaire   +1 more source

Effect of lncRNA ZEB1-AS1 on proliferation, invasion and apoptosis of glioma U87 cells

open access: yesOncology Letters, 2019
This study aimed to investigate the effect of LncRNA ZEB1-AS1 on the proliferation, invasion and apoptosis of human glioma U87 cells. U87 glioma cells were divided into three groups. The Si group was transfected with LncRNA ZEB1-AS1 specific SiRNA. The NC group was transfected with non-specific scramble siRNA, and untransfected glioma cells were used ...
Zhang, Wei, Xiong, Lijun
openaire   +3 more sources

Dipeptidyl peptidase IV in two human glioma cell lines

open access: yesEuropean Journal of Histochemistry, 2009
There is growing evidence that dipeptidyl peptidase IV [DPP-IV, EC 3.4.14.5] takes part in the metabolism of biologically active peptides participating in the regulation of growth and transformation of glial cells.
A Sedo   +5 more
doaj   +1 more source

miR-92 regulates the proliferation, migration, invasion and apoptosis of glioma cells by targeting neogenin

open access: yesOpen Medicine, 2020
This study aimed to explore the pathological mechanism in regulating glioma progression. The expression of miR-92 and neogenin was evaluated by qRT-PCR and western blot.
Wang Yi   +4 more
doaj   +1 more source

Anticancer Molecular Mechanisms of Phytosterols: An Updated Review on Clinical Trials

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
Phytosterols, a form of naturally occurring substance structurally related to cholesterol, have been getting considerable interest due to their possible anticancer properties. Phytosterols induce apoptosis, block the cell cycle, and abrogate the invasion and metastasis of cancer cells, offering a multi‐manifestation treatment of cancer.
Muhammad Shahbaz   +14 more
wiley   +1 more source

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