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Regulation of ubiquinone metabolism
Free Radical Biology and Medicine, 2000Interest in ubiquinone (UQ) has increased during recent years, mainly because of its antioxidant function and its use as a dietary supplement. However, our knowledge of the biosynthesis, catabolism, and regulation of this lipid in mammalian tissues is quite limited.
G, Dallner, P J, Sindelar
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On the biosynthesis of ubiquinone (50)
Archives of Biochemistry and Biophysics, 1959Abstract It is shown that radioactive mevalonic acid is utilized for the synthesis of ubiquinone in the rat. 2,3-Dimethoxy-5-methyl-1,4-benzoquinone and dl -α-tocopherol are not precursors of the quinoid ring system. With progressive vitamin A depletion, the incorporation of mevalonic acid into ubiquinone of rat liver is enhanced.
U, GLOOR, O, WISS
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Ubiquinones and Ubichromenols in the Rat
Nature, 1960UBIQUINONE, a naturally occurring quinone of considerable biological interest, was first isolated by Morton et al. 1, who found it in many kinds of animal tissue. Lester et al. 2 have shown that a series of such quinones exist, and have isolated, from different organisms, five compounds of general formula :
A T, DIPLOCK +4 more
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Ubiquinone and Tocopherol in Birds
Nature, 1961UNLIKE the rat and the rabbit, it seems from nutritional studies made by several groups of workers that the chicken needs little vitamin E, providing its diet contains an adequate supply of selenium and only limited amounts of unsaturated fat1–3. Since tissue-levels of ubiquinone in the rat4 and rabbit5 are high compared with those given for some other
J, BUNYAN +3 more
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Rush desensitization with ubiquinone
Allergy, 1997UBIQUINONE
Schiavino, Domenico +4 more
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Nihon rinsho. Japanese journal of clinical medicine, 1993
Recent topics on the biochemical and clinical aspects of ubiquinone are reviewed in this paper. Dallner and his colleagues have demonstrated that ubiquinone is synthesized, not only in mitochondria, but also on the endoplasmic reticulum-Golgi system of the rat liver.
T, Okamoto, T, Takahashi, T, Kishi
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Recent topics on the biochemical and clinical aspects of ubiquinone are reviewed in this paper. Dallner and his colleagues have demonstrated that ubiquinone is synthesized, not only in mitochondria, but also on the endoplasmic reticulum-Golgi system of the rat liver.
T, Okamoto, T, Takahashi, T, Kishi
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Interaction of ubiquinone and vitamin K3 with mitochondrial succinate-ubiquinone oxidoreductase
Biochemical and Biophysical Research Communications, 1992Two new methods have been devised for measuring fumarate reduction by beef heart succinate-ubiquinone oxidoreductase with quinols as electron donors. In one assay the quinone is maintained in the reduced state by coupling fumarate reduction with the DT-diaphorase reaction, in the other assay by the presence of excess dithionite. The advantages of these
A B, Kotlyar, M, Gutman, B A, Ackrell
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Revista de neurologia, 1999
Review of ubiquinone-10 metabolism and functions in humans, focusing its implication in the pathogenesis and physiopathology of mitochondrial encephalomyopathies.Ubiquinone-10 is an endogenously synthesized lipid with a wide distribution in tissues. Tyrosine and acetil-CoA are involved in ubiquinone biosynthesis.
Artuch R +4 more
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Review of ubiquinone-10 metabolism and functions in humans, focusing its implication in the pathogenesis and physiopathology of mitochondrial encephalomyopathies.Ubiquinone-10 is an endogenously synthesized lipid with a wide distribution in tissues. Tyrosine and acetil-CoA are involved in ubiquinone biosynthesis.
Artuch R +4 more
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Biosynthesis of Ubiquinones in Animals
1967Publisher Summary This chapter describes the biosynthesis of ubiquinones in animals. The biosynthesis of ubiquinones or coenzyme Q in animal tissues is a multienzymatic process involving the assembly of portions of the molecule derived from various precursors that may be demonstrated in whole animals and tissue slices.
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Ubiquinone and tocopherylquinone
Biochimica et Biophysica Acta, 1958J, BOUMAN +3 more
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