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Understanding Ubiquinone

open access: yesTrends in Cell Biology, 2016
Ubiquinone (UQ; also known as coenzyme Q; CoQ) is a mobile component of the mitochondrial electron transport chain, where it acts as a pro-oxidant in its ubisemiquinone state. Despite this, UQ is also believed to be a membrane antioxidant. These properties place UQ at the center of hotly debated questions about how mitochondria and reactive oxygen ...
Ying Wang, Siegfried Hekimi
exaly   +4 more sources
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Regulation of ubiquinone metabolism

Free Radical Biology and Medicine, 2000
Interest in ubiquinone (UQ) has increased during recent years, mainly because of its antioxidant function and its use as a dietary supplement. However, our knowledge of the biosynthesis, catabolism, and regulation of this lipid in mammalian tissues is quite limited.
G, Dallner, P J, Sindelar
openaire   +2 more sources

Biosynthesis of Ubiquinone

1983
Publisher Summary This chapter discusses the biosynthesis of ubiquinone. Ubiquinone serves as a lipid-soluble electron carrier in the membrane-bound electron transport chains of both prokaryotes and eukaryotes. Eighty-five percent of cell ubiquinon is located in the mitochondria or equivalent membrane system.
R E, Olson, H, Rudney
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Ubiquinone in the retina

Vision Research, 1968
Abstract Microspectrophotometric examination of retinal cells shows an absorbance maximum at 282 nm and a shoulder at 275 nm, the latter possibly due to ubiquinone. Extraction of bovine retinal cell outer segments and retinal cells free of outer segments, however, failed to reveal any ubiquinone; an upper limit of 0.6 n mole ubiquinone per eye being ...
G, Entine, P A, Liebman, B T, Storey
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Rush desensitization with ubiquinone

Allergy, 1997
UBIQUINONE
Schiavino, Domenico   +4 more
openaire   +3 more sources

[Ubiquinones].

Nihon rinsho. Japanese journal of clinical medicine, 1993
Recent topics on the biochemical and clinical aspects of ubiquinone are reviewed in this paper. Dallner and his colleagues have demonstrated that ubiquinone is synthesized, not only in mitochondria, but also on the endoplasmic reticulum-Golgi system of the rat liver.
T, Okamoto, T, Takahashi, T, Kishi
openaire   +1 more source

Kinetics of ubiquinone reduction by the resolved succinate: Ubiquinone reductase

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1982
A significant lag in the thenoyltrifluoroacetone (TTFA)-sensitive succinate: ubiquinone reductase activity was observed when a ubiquinone-deficient resolved preparation of the enzyme was assayed in the presence of exogenous ubiquinone-2 (Q2) and 2,6-dichlorophenolindophenol.
V G, Grivennikova, A D, Vinogradov
openaire   +2 more sources

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