Results 11 to 20 of about 66,565 (306)
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
Hepatology, EarlyView., 2022 RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso +16 more
wiley +1 more source
Ubiquinone [Q10] and Dentate Gyrus Ischaemia Reperfusion Injury in a Rat Model of Brain Ischaemia
Archives of Advances in Biosciences, 2023 Introduction: This research was conducted to evaluate the effect of ubiquinone following ischemia/reperfusion on dentate gyrus in Wistar rats. Materials and Methods: Twenty-four Rats were randomly assigned to four groups [n=6].
Niloofar Talebi Tadi +3 more
doaj +1 more source
Multistationary and Oscillatory Modes of Free Radicals Generation by the Mitochondrial Respiratory Chain Revealed by a Bifurcation Analysis [PDF]
, 2012 The mitochondrial electron transport chain transforms energy satisfying cellular demand and generates reactive oxygen species (ROS) that act as metabolic signals or destructive factors.
Mark F. Schumaker +6 more
core +5 more sources
Plasma coenzyme Q10 levels in type 2 diabetic patients with retinopathy [PDF]
International Journal of Ophthalmology, 2013 AIM: To determine the relationship between proliferative diabetic retinopathy (PDRP) and plasma coenzyme Q10(CoQ10) concentration.METHODS: Patients with type 2 diabetes and PDRP were determined to be the case group (n=50).
Orhan Ates +9 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 ObjectiveEffective interventions that might limit myocardial ischemia-reperfusion (I/R) injury are still lacking. Coenzyme Q10 (CoQ10) may exert cardioprotective actions that reduce myocardial I/R injury.
Kamal Awad +5 more
doaj +1 more source
Trends in Cell Biology, 2016 Ubiquinone (UQ; also known as coenzyme Q; CoQ) is a mobile component of the mitochondrial electron transport chain, where it acts as a pro-oxidant in its ubisemiquinone state. Despite this, UQ is also believed to be a membrane antioxidant. These properties place UQ at the center of hotly debated questions about how mitochondria and reactive oxygen ...
Wang, Ying, Hekimi, Siegfried
openaire +3 more sources
Tuning ubiquinone position in biomimetic monolayer membranes [PDF]
, 2017 Artificial lipid bilayers have been extensively studied as models that mimic natural membranes (biomimetic membranes). Several attempts of biomimetic membranes inserting ubiquinone (UQ) have been performed to enlighten which the position of UQ in the ...
Guaus Guerrero, Ester +2 more
core +2 more sources
BMC Cancer, 2020 Background Cancer development is mediated by oxidative stress and inflammation, which may correlate with metabolic disorders. The aim of this study was to evaluate antioxidant vitamins status and metabolic parameters in patients with oral cancer ...
Man-Yee Chan +6 more
doaj +1 more source
mBio, 2022 Prenyldiphosphate synthases catalyze the reaction of allylic diphosphates with one or more isopentenyl diphosphate molecules to form compounds such as farnesyl diphosphate, used in, e.g., sterol biosynthesis and protein prenylation, as well as longer ...
Melissa A. Sleda +9 more
doaj +1 more source
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2018 Background Ubiquinone has antioxidant properties and has been linked to cognitive performance in some neuropsychiatric disorders. Its role in specific learning disorder manifestations has not been previously investigated. Therefore, the aim of this study
Ehab Ragaa Abdelraouf +6 more
doaj +1 more source