The DSmurf Ubiquitin-Protein Ligase Restricts BMP Signaling Spatially and Temporally during Drosophila Embryogenesis [PDF]
, 2001 Steven D. Podos +3 more
openalex +1 more source
Structure of a c-Cbl–UbcH7 Complex RING Domain Function in Ubiquitin-Protein Ligases
Cell, 2000 N. Zheng +3 more
semanticscholar +1 more source
Localization of the Rsp5p Ubiquitin-Protein Ligase at Multiple Sites within the Endocytic Pathway [PDF]
, 2001 Guangli Wang +5 more
openalex +1 more source
On an RNA-membrane protogenome [PDF]
arXivSelected ribonucleotide sequences bind well to zwitterionic phospholipid bilayer membranes, though randomized RNAs do not. There are no evident repeated sequences in selected membrane binding RNAs. This implies small and varied motifs responsible for membrane affinity. Such subsequences have been partially defined. Bound RNAs require divalents like Mg2+
arxiv
Kinetic Analysis of the Conjugation of Ubiquitin to Picornavirus 3C Proteases Catalyzed by the Mammalian Ubiquitin-protein Ligase E3α [PDF]
, 2001 T. Glen Lawson +4 more
openalex +1 more source
SE(3)-Equivariant Ternary Complex Prediction Towards Target Protein Degradation [PDF]
arXivTargeted protein degradation (TPD) induced by small molecules has emerged as a rapidly evolving modality in drug discovery, targeting proteins traditionally considered "undruggable". Proteolysis-targeting chimeras (PROTACs) and molecular glue degraders (MGDs) are the primary small molecules that induce TPD.
arxiv
A Molecular Basis for Stabilization of the von Hippel-Lindau (VHL) Tumor Suppressor Protein by Components of the VHL Ubiquitin Ligase [PDF]
, 2002 Takumi Kamura +3 more
openalex +1 more source
Structural ubiquitin contributes to K48 linkage specificity of the HECT ligase Tom1
Cell ReportsSummary: Homologous to E6AP C terminus (HECT) ubiquitin ligases play key roles in essential pathways such as DNA repair, cell cycle control, or protein quality control. Tom1 is one of five HECT ubiquitin E3 ligases in budding yeast S.
Katrina Warner +8 more
doaj