Results 211 to 220 of about 525,256 (308)

Enhanced levels of Pis1p (phosphatidylinositol synthase) improve the growth of Saccharomyces cerevisiae cells deficient in Rsp5 ubiquitin ligase

, 2006
Paweł Kaliszewski, Thierry Ferreira, Beata Gajewska, Anna Szkopińska, Thierry Bergès, Teresa Żołądek   +5 more
openalex   +1 more source

Targeting DESI2 as a Novel Therapeutic Strategy for JAK2‐Mutant Leukemias

Advanced Science, EarlyView.
Mass spectrometry‐based proteomics identify DESI2 as a novel component of the JAK2‐V617F complex, which associates with and stabilizes mutant JAK2 through deSUMOylation and deubiquitination, therefore promoting JAK2 mutant cell growth and MPN disease onset in vivo.
Husheng Mei, Wuqiang Wen, Wenjun Zhang, Shujing Zhang, Ting Sun, Guiming Li, Jing Zhang, Shuang Qi, Jie Zhou, Bing Li, Yunshuo Zhao, Xiaotong Chen, Bowen Li, Yiying Xue, Wang Lu, Yanli Sun, Jingyao Wang, Hengyue Shan, Shengzhe Zhang, Yushan Huang, Yisa Chen, Wenchao Wang, Qingsong Liu, Wenchao Lu, Li Tan, Yi Ding, Jianfei Fu, Jun Long, Lei Zhang, Baobing Zhao, Aibin Liang, Baishan Jiang, Jing Yang   +32 more
wiley   +1 more source

Hypoxia Increases Cardiac Proteasomal Activity and Differentially Modulates Cullin-RING E3 Ligases in the Naked Mole-Rat <i>Heterocephalus glaber</i>. [PDF]

Muscles
Ingelson-Filpula WA, Kadamani KL, Ojaghi M, Pamenter ME, Storey KB.   +4 more
europepmc   +1 more source

Non-radioactive in vitro PINK1 Kinase Assays Using Ubiquitin or Parkin as Substrate

, 2016
Fabienne C. Fiesel, Roman Hudec, Wolfdieter Springer   +2 more
openalex   +2 more sources

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Mebendazole inhibits PELI3-mediated ubiquitination of TRADD in non-small cell lung cancer cells. [PDF]

Front Oncol
Li F, Li X, Li H, Li S, Liu Y, Bai X, Qi T, Zhao X, He Y.   +8 more
europepmc   +1 more source

EGR Proteins Mediate Interferon‐Independent Anti‐HSV‐1 Responses Through Viral and Host Targets

Advanced Science, EarlyView.
Early antiviral responses are typically mediated by interferons. However, during HSV‐1 infection, host early growth response (Egr) genes, which are not interferon‐stimulated genes, are quickly induced by viral protein ICP0. EGR proteins, in turn, suppress viral lytic infection by activating viral latency‐associated (LAT) and host immune regulatory ...
Shuaishuai Wang, Fujun Hou, Xunuo Jin, Yuhang Xiang, Dongli Pan   +4 more
wiley   +1 more source

Corrigendum: Ribosomal protein L40e fused with a ubiquitin moiety is essential for the vegetative growth, morphological homeostasis, cell cycle progression, and pathogenicity of Cryptococcus neoformans

Frontiers in Microbiology
Jingyu Zhao, Jingyu Zhao, Yali Yang, Yali Yang, Yibin Fan, Jiu Yi, Chao Zhang, Zhongkai Gu, Weihua Pan, Julin Gu, Wanqing Liao, Wei Fang   +11 more
doaj   +1 more source

Diacetyl-induced bronchiolitis obliterans involves ubiquitin C upregulation and fibrosis-related gene activation in rats. [PDF]

Front Pharmacol
Wang H, Jiang W, Xiao J, Geng Y, Ye Q, Ge W.   +5 more
europepmc   +1 more source

2P066 Folding dynamics of ubiquitin after rapid mixing detected by single molecule fluorescence spectroscopy(01C. Protein: Property,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

, 2014
Masataka Saito, Eric Chen, Po‐Ting Chen, Rita P.‐Y. Chen, Kiyoto Kamagata, Hiroyuki Oikawa, Satoshi Takahashi   +6 more
openalex   +2 more sources