Results 201 to 210 of about 274,920 (356)

Smad Ubiquitination Regulatory Factor 2 Promotes Metastasis of Breast Cancer Cells by Enhancing Migration and Invasiveness [PDF]

, 2009
Chaoyang Jin, Yu-an Yang, Miriam R. Anver, Nicole Morris, Xiangchun Wang, Ying E. Zhang   +5 more
openalex   +1 more source

Covalent Reprogramming of Kinase Binders to Modulate Protein Abundance

Advanced Science, EarlyView.
Electrophilic remodeling of a broad‐spectrum kinase binder reveals how subtle chemical changes reprogram protein fate. An acrylamide analog of a multi‐kinase binder selectively stabilizes Aurora kinase A (AURKA) by suppressing its ubiquitination, while a short‐linker variant converts this stabilizer into a degrader.
Chen Mozes, Xiaokang Jin, Miguel A. Campos, Chen Zhou, Xiaoyu Zhang   +4 more
wiley   +1 more source

Transcriptional and post-translational regulation of aquaporins in plants. [PDF]

Stress Biol
Yang C, Medison MB, Li Y, Shi Y, Medison RG, Liu H, Wang Y.   +6 more
europepmc   +1 more source

Regulation of AMPA Receptor Trafficking by Protein Ubiquitination [PDF]

, 2017
Jocelyn Widagdo, Sumasri Guntupalli, Se‐Eun Jang, Victor Anggono   +3 more
openalex   +1 more source

Ubiquitin [PDF]

, 2020
openaire   +1 more source

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

K48 and K63 linkage-competed ubiquitination of BECN1 promotes circPDE4D-mediated autophagy in chronic obstructive pulmonary disease. [PDF]

Cell Death Dis
Chen TT, Wang MY, Kang JY, Ou GC, Wang R, Zhang DW, Ye JJ, Fei GH.   +7 more
europepmc   +1 more source

Ubiquitination by March-I prevents MHC class II recycling and promotes MHC class II turnover in antigen-presenting cells [PDF]

, 2015
Kyungjin Cho, Even Walseng, Satoshi Ishido, Paul A. Roche   +3 more
openalex   +1 more source

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

Advanced Science, EarlyView.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang, Zenghui Cui, Yunkai Zhang, Zhiqing Li, Xuetao Cao   +4 more
wiley   +1 more source

E3 ubiquitin ligase NEDD4 inhibits PEDV infection through ubiquitination and degradation of the viral primase NSP8. [PDF]

J Virol
Guo X, Zhao X, He J, Lu Y, Jin S, Ma Z, Li Z, Zheng Z, Li Y, Feng Y, Xu L, Liu X, Zhang J, Wei Z, Zheng H, Xiao S.   +15 more
europepmc   +1 more source