Proteome and Ubiquitinome Analyses Reveal the Involvement of Ubiquitination in Resistance to Maize Lethal Necrosis [PDF]
Molecular Plant PathologyThis study analysed the proteome and ubiquitinome of SCMV‐ and/or MCMV‐infected maize plants and demonstrated the role of ZmGOX1 in the maize response to viral infections. ABSTRACT The co‐infection of maize chlorotic mottle virus (MCMV) and sugarcane mosaic virus (SCMV) causes maize lethal necrosis (MLN), which seriously affects the yield and quality ...
Zihao Xia, Mengnan An, Kaiqiang Hao
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Comparative ubiquitinome analysis reveals the roles of protein ubiquitination in the heat stress response from Metarhizium robertsii [PDF]
Applied and Environmental MicrobiologyProtein ubiquitination plays a vital role in the stress response of diverse filamentous fungi. However, few reports are available on fungal insect pathogens, including Metarhizium.
Jueping Song +5 more
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Comprehensive characterization of ubiquitinome of human colorectal cancer and identification of potential survival-related ubiquitination [PDF]
Journal of Translational Medicine, 2022 Background According to the Global Cancer Statistics in 2020, the incidence and mortality of colorectal cancer (CRC) rank third and second among all tumors.
Yong Dai, Jingquan He, Yin Lianghong
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Proteome and ubiquitinome analyses of the brain cortex in K18-hACE2 mice infected with SARS-CoV-2 [PDF]
IScienceSummary: Clinical research indicates that SARS-CoV-2 infection is linked to several neurological consequences, and the virus is still spreading despite the availability of vaccinations and antiviral medications. To determine how hosts respond to SARS-CoV-
Jiangning Liu +2 more
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Tomato ubiquitinome in response to ‘Candidatus Liberibacter solanacearum’ haplotypes A and B [PDF]
Crop Health‘Candidatus Liberibacter solanacearum’ (Lso) is a devastating bacterial pathogen of crops transmitted by psyllids. Previously, a link between changes in ubiquitination and the progression of diseases caused by Lso was established.
Julien G. Levy +4 more
doaj +3 more sources
Light‐Activatable Ubiquitin for Studying Linkage‐Specific Ubiquitin Chain Formation Kinetics [PDF]
Advanced ScienceUbiquitination is a dynamic post‐translational modification governing protein abundance, function, and localization in eukaryotes. The Ubiquitin protein is conjugated to lysine residues of target proteins, but can also repeatedly be ubiquitinated itself,
Sudakshina Banerjee +7 more
doaj +3 more sources
Ubiquitinome Analysis Uncovers Alterations in Synaptic Proteins and Glucose Metabolism Enzymes in the Hippocampi of Adolescent Mice Following Cold Exposure [PDF]
CellsCold exposure exerts negative effects on hippocampal nerve development in adolescent mice, but the underlying mechanisms are not fully understood. Given that ubiquitination is essential for neurodevelopmental processes, we attempted to investigate the ...
Shize Li, Huanmin Yang, Jingjing Lu
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FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination [PDF]
Advanced ScienceMitochondrial dysfunction is related to etiopathogenesis and progression of heart failure (HF). The underlying molecular mechanisms are not fully understood. Transcription factor FOXM1 plays an essential role in cardiovascular development.
Shuai Song +17 more
doaj +3 more sources
Cancer Communications, 2021 Background Tumor metastasis is a major factor for poor prognosis of hepatocellular carcinoma (HCC), but the relationship between ubiquitination and metastasis need to be studied more systematically.
Feiyang Ji +8 more
doaj +2 more sources
Frontiers in Microbiology, 2022 Herpes simplex virus 1 (HSV-1) can productively infect multiple cell types and establish latent infection in neurons. Infected cell protein 0 (ICP0) is an HSV-1 E3 ubiquitin ligase crucial for productive infection and reactivation from latency.
Dongli Pan, Zeyu Sun, Xiyuan Yang
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