Results 41 to 50 of about 202,310 (299)
, 2011 In this chapter, we describe a method for detecting the ubiquitination status of G protein-coupled receptors (GPCRs). This involves co-expression of a GPCR with an epitope-tagged ubiquitin construct in a -heterologous mammalian expression system. Stimulus-dependent modification of the GPCR by -ubiquitin is detected by immunoprecipitation and subsequent
Adriana, Caballero, Adriano, Marchese
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Ubiquitinome Profiling Reveals the Landscape of Ubiquitination Regulation in Rice Young Panicles
Genomics, Proteomics & Bioinformatics, 2020 Ubiquitination, an essential post-transcriptional modification (PTM), plays a vital role in nearly every biological process, including development and growth.
Liya Zhu +9 more
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Cells, 2022 Epigenetic regulation plays an essential role in driving precise transcriptional programs during development and homeostasis. Among epigenetic mechanisms, histone mono-ubiquitination has emerged as an important post-transcriptional modification.
Liat Oss-Ronen, Tzlil Sarusi, Idan Cohen
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Mechanisms of mono- and poly-ubiquitination: Ubiquitination specificity depends on compatibility between the E2 catalytic core and amino acid residues proximal to the lysine [PDF]
, 2010 Ubiquitination involves the attachment of ubiquitin to lysine residues on substrate proteins or itself, which can result in protein monoubiquitination or polyubiquitination. Ubiquitin attachment to different lysine residues can generate diverse substrate-
Boris Sarcevic +7 more
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In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones.
, 2019 peer reviewedUbiquitination is a post-translational modification that plays important roles in various signaling pathways and is notably involved in the coordination of chromatin function and DNA-associated processes.
Boubekeur, Amina +8 more
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International Journal of Molecular Sciences, 2018 Ever since the discovery of ubiquitin in 1975[...]
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HIV Nef-mediated Ubiquitination of BCL2: Implications in Autophagy and Apoptosis
Frontiers in Immunology, 2021 Ubiquitination is a process that acts upon every step of the HIV replication cycle. The activity, subcellular localization, and stability of HIV dependency factors as well as negative modulators can be affected by ubiquitination.
Sergio Castro-Gonzalez +5 more
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Analysis of Flagellar Protein Ubiquitination
, 2013 Flagella/cilia are conserved organelles existing in unicellular protists and multicellular animals, where they perform essential motile and sensory functions.
Huan Long +3 more
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Communications BiologyThe divergence in pathogenicity among human coronaviruses (HCoVs), from causing common cold to lethal pneumonia, may indicate distinct viral immune evasion strategies.
Xinming Fu +3 more
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βTrCP-mediated proteolysis of NF-kB1 p105 requires phosphorylation of p105 serines 927 and 932 [PDF]
, 2003 This work was supported by the U.K. Medical Research Council, the Arthritis Research Campaign (project grant L0536 to V.L.), and the AINP consortium, EC—5th framework.NF-κB1 p105 functions both as a precursor of NF-κB1 p50 and as a cytoplasmic inhibitor ...
Ben-Neriah, Yinon +9 more
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